Zobrazeno 1 - 10
of 13
pro vyhledávání: '"M. Ann Clark"'
Publikováno v:
Gastroenterology. 120:439-448
Background & Aims: Intestinal glycine transport is involved in nutrient absorption and enterocyte homeostasis, particularly for glutathione synthesis. The primary aim of this study was to characterize the mechanism of postabsorptive (basolateral) gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46857c0ddeaaeefa02dc319b67c5b365
https://doi.org/10.1053/gast.2001.21207
https://doi.org/10.1053/gast.2001.21207
Publikováno v:
Histochemistry and Cell Biology. 114:311-321
Human palatine tonsils are clinically important due to their susceptibility to tonsillitis and association with other local and systemic diseases. Paradoxically, the tonsils function as antigen sampling sites of the mucosal immune system and, consequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d41097e6f9d95e231e13250f25859f6
https://doi.org/10.1007/s004180000198
https://doi.org/10.1007/s004180000198
Publikováno v:
The Histochemical Journal. 26:271-280
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d910e76aaff4a175e4f837b87df43d55
https://doi.org/10.1007/bf02388442
https://doi.org/10.1007/bf02388442
Autor:
Mark A. Jepson, M. Ann Clark
Publikováno v:
International journal of medical microbiology : IJMM. 293(1)
M cells are located in the epithelia overlying mucosa-associated lymphoid tissues such as Peyer's patches where they function as the antigen sampling cells of the mucosal immune system. Paradoxically, some pathogens exploit M cells as a route of inva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53738f9a71e9192395c0a4ffb38fe0a7
https://pubmed.ncbi.nlm.nih.gov/12755364
https://pubmed.ncbi.nlm.nih.gov/12755364
Publikováno v:
Vaccine. 20(1-2)
Due to their transcytotic capability, intestinal M cells may represent an efficient potential route for oral vaccine delivery. We previously demonstrated that the lectin Ulex europaeus agglutinin 1 (UEA1, specific for α-l-fucose residues) selectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f03ced98f49523f45a7bb762d46e6c9
https://pubmed.ncbi.nlm.nih.gov/11567766
https://pubmed.ncbi.nlm.nih.gov/11567766
Publikováno v:
Advanced drug delivery reviews. 43(2-3)
Absorption of drugs and vaccines at mucosal surfaces may be enhanced by conjugation to appropriate bioadhesins which bind to mucosal epithelia. Bioadhesins might also permit cell- and site-selective targeting. One approach is to exploit surface carbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc042820832465b9660f08e5d739424c
https://pubmed.ncbi.nlm.nih.gov/10967227
https://pubmed.ncbi.nlm.nih.gov/10967227
Autor:
M. Ann Clark, Mark A. Jepson
Publikováno v:
Trends in microbiology. 6(9)
In addition to sampling antigens, M cells are a common route for pathogen invasion. Recent studies have partly defined the mechanisms by which pathogens interact with and exploit M cells as a gateway into the host. New research tools are facilitating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ceaa1ef58a77178bcac1582451bb4df
https://pubmed.ncbi.nlm.nih.gov/9778729
https://pubmed.ncbi.nlm.nih.gov/9778729
Autor:
KA Reed, M. Ann Clark, Christoph J. Hueck, Samuel I. Miller, Mark A. Jepson, Barry H. Hirst, Trevor A. Booth
Publikováno v:
Infection and immunity. 66(5)
The formation of filamentous appendages on Salmonella typhimurium has been implicated in the triggering of bacterial entry into host cells (C. C. Ginocchio, S. B. Olmsted, C. L. Wells, and J. E. Galán, Cell 76:717–724, 1994). We have examined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec64c44985ae934a118b09ea40fce6f1
https://pubmed.ncbi.nlm.nih.gov/9573083
https://pubmed.ncbi.nlm.nih.gov/9573083
Quantitative analysis of Yersinia pseudotuberculosis infection of murine gut loops revealed that significantly more wild-type bacteria associated with Peyer’s patch M cells than with dome enterocytes or goblet cells. An invasin-deficient mutant was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d21bc290b27b62015e761fa549ad5f
https://europepmc.org/articles/PMC108039/
https://europepmc.org/articles/PMC108039/
Publikováno v:
Infection and immunity. 66(2)
In the mouse model of Salmonella typhimurium infection, the specialized antigen-sampling intestinal M cells are the primary route of Salmonella invasion during the early stages of infection. Under certain experimental conditions, M-cell invasion is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7293d6b8976d60d66ed90e86ccab2de
https://pubmed.ncbi.nlm.nih.gov/9453633
https://pubmed.ncbi.nlm.nih.gov/9453633