Zobrazeno 1 - 4
of 4
pro vyhledávání: '"M. Angelica Martinez Gakidis"'
Autor:
Michael Glogauer, M. Angelica Martinez Gakidis, Joan S. Brugge, Julie L. Wilsbacher, Amy B. Hall, Wojciech Swat, Sizhen Gao
Publikováno v:
Immunity. 24:305-316
Vav guanine nucleotide exchange factors (GEFs) have been implicated in cell adhesion by integrin and immune response receptors through the regulation of Rho GTPases. Here, we examine the role of Vav and Rho GTPases in phagocytosis by using primary mu
Autor:
Mamie Z. Li, Zhenming Zhao, Stephen J. Elledge, H. Benjamin Larman, Santosh Kesari, Uri Laserson, Nicole L. Solimini, Emily M LeProust, George M. Church, M. Angelica Martinez Gakidis, Alberto Ciccia
Publikováno v:
Nature biotechnology
Immune responses targeting self-proteins (autoantigens) can lead to a variety of autoimmune diseases. Identification of these antigens is important for both diagnostic and therapeutic reasons. However, current approaches to characterize autoantigens
Autor:
Sheri L. Moores, Bin Zhang, M. Angelica Martinez Gakidis, Tanya N. Mayadas, Joan S. Brugge, Wojciech Swat, Xavier Cullere, Timothy S. Olson, Klaus Ley, Julie L. Wilsbacher
Publikováno v:
The Journal of Cell Biology
Integrin regulation of neutrophils is essential for appropriate adhesion and transmigration into tissues. Vav proteins are Rho family guanine nucleotide exchange factors that become tyrosine phosphorylated in response to adhesion. Using Vav1/Vav3-def
Autor:
Hong Zhu, M. Angelica Martinez Gakidis, Junying Yuan, A Rao, Zhen Yang, C Yuan, Fumio Ikegami, T Sekine, D Gong, Vigo Heissmeyer, M Kobori, Y-K Jung
Publikováno v:
Cell death and differentiation. 11(1)
Caspase-11 is a key regulator of proinflammatory cytokine IL-1beta maturation and pathological apoptosis. Caspase-11 is not expressed in most tissues under normal condition, but highly inducible upon pathological stimulation such as in the presence o