Zobrazeno 1 - 10
of 129
pro vyhledávání: '"M. Angela Nieto"'
Intron detention tightly regulates the stemness/differentiation switch in the adult neurogenic niche
Autor:
Ainara González-Iglesias, Aida Arcas, Ana Domingo-Muelas, Estefania Mancini, Joan Galcerán, Juan Valcárcel, Isabel Fariñas, M. Angela Nieto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The adult mammalian brain retains some capacity to replenish neurons and glia, holding promise for brain regeneration. Thus, understanding the mechanisms controlling adult neural stem cell (NSC) differentiation is crucial. Paradoxically, adu
Externí odkaz:
https://doaj.org/article/4116623c87df4b3fb1ecede9d29f1a58
Autor:
Ainara González-Iglesias, Aida Arcas, Ana Domingo-Muelas, Estefania Mancini, Joan Galcerán, Juan Valcárcel, Isabel Fariñas, M. Angela Nieto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5687f0b58b1a4ebfbe36976c0ac84aef
Autor:
Jennifer A. Mitchel, Amit Das, Michael J. O’Sullivan, Ian T. Stancil, Stephen J. DeCamp, Stephan Koehler, Oscar H. Ocaña, James P. Butler, Jeffrey J. Fredberg, M. Angela Nieto, Dapeng Bi, Jin-Ah Park
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
During repair, development, or cancer metastasis, epithelial cells can become migratory through partial or full epithelial to mesenchymal transition (EMT). Here, the authors report that differentiated epithelial collectives may undergo cooperative an
Externí odkaz:
https://doaj.org/article/ab4af25389c54c6284d0fdfba0eb6c62
Autor:
Hassan Fazilaty, Luciano Rago, Khalil Kass Youssef, Oscar H. Ocaña, Francisco Garcia-Asencio, Aida Arcas, Juan Galceran, M. Angela Nieto
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
EMT is a developmental process that is aberrantly activated in metastasizing cancer cells, but how multiple transcription factors regulate EMT is unclear. Here, the authors uncover a gene regulatory network between Prrx1 and Snail1 that selects EMT m
Externí odkaz:
https://doaj.org/article/08e953ed2ee54167890462b34ebbf788
Autor:
Varsha Prakash, Brittany B. Carson, Jennifer M. Feenstra, Randall A. Dass, Petra Sekyrova, Ayuko Hoshino, Julian Petersen, Yuan Guo, Matthew M. Parks, Chad M. Kurylo, Jake E. Batchelder, Kristian Haller, Ayako Hashimoto, Helene Rundqivst, John S. Condeelis, C. David Allis, Denis Drygin, M. Angela Nieto, Michael Andäng, Piergiorgio Percipalle, Jonas Bergh, Igor Adameyko, Ann-Kristin Östlund Farrants, Johan Hartman, David Lyden, Kristian Pietras, Scott C. Blanchard, C. Theresa Vincent
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Ribosomal DNA transcription is essential for cell growth and division. Here, the authors show that EMT is accompanied by Snail binding to rDNA operons and Rictor association with nucleoli to fuel an induction of ribosome biogenesis during G1/S cell c
Externí odkaz:
https://doaj.org/article/d55a3dcbab384f5da902c83d1a827b47
Publikováno v:
Cell Reports, Vol 5, Iss 3, Pp 727-737 (2013)
Exportin5 mediates the nuclear export of double-stranded RNAs, including pre-microRNAs, adenoviral RNAs, and tRNAs. When tRNAs are aminoacylated, the Exportin5-aminoacyl (aa)-tRNA complex recruits and coexports the translation elongation factor eEF1A
Externí odkaz:
https://doaj.org/article/1238dbdbf7c546c7876ac994a11e84dc
Publikováno v:
Cell Reports, Vol 8, Iss 3, p 922 (2014)
Externí odkaz:
https://doaj.org/article/1e6b61c02ee147d7bf734d689160352a
Autor:
Marta Arumi-Planas, Francisco Javier Rodriguez-Baena, Francisco Cabello-Torres, Francisco Gracia, Cristina Lopez-Blau, M. Angela Nieto, Berta Sanchez-Laorden
Melanoma is an aggressive form of skin cancer due to its high metastatic abilities and resistance to therapies. Melanoma cells reside in a heterogeneous tumour microenvironment that acts as a crucial regulator of its progression. Snail1 is an epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72b707338b8bfe4784cc64529f3f6262
https://doi.org/10.1101/2022.11.23.517623
https://doi.org/10.1101/2022.11.23.517623
Autor:
M. Angela Nieto, Berta Sanchez-Laorden
Publikováno v:
EMBO Molecular Medicine. 14
News & Views.
Melanoma is the most aggressive form of skin cancer. Together with the recent advances in immunotherapy, targeted therapy with inhibitors of the Mitogen Activated Protein Kinase (MAPKi) pathway including BRAF and MEK inhibitors has
Melanoma is the most aggressive form of skin cancer. Together with the recent advances in immunotherapy, targeted therapy with inhibitors of the Mitogen Activated Protein Kinase (MAPKi) pathway including BRAF and MEK inhibitors has
Autor:
M. Angela Nieto, Khalil Kass Youssef
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Refers to: Debadrita Bhattacharya, Ana Paula Azambuja, Marcos Simoes-Costa Metabolic Reprogramming Promotes Neural Crest Migration via Yap/Tead Signaling Developmental Cell, Volume 53, Issue 2, 20 April 2020, Pages 199-211.e6
Aerobic glycolysis,
Aerobic glycolysis,