Zobrazeno 1 - 10
of 45
pro vyhledávání: '"M. Ali Al-Radhawi"'
Derivation of stationary distributions of biochemical reaction networks via structure transformation
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Hong, Kim and colleagues develop a method for analytically deriving the stationary distributions of stochastic biochemical reaction networks using network structure transformation. They provide this method in a user-friendly computational package, CA
Externí odkaz:
https://doaj.org/article/f3360ccb16ac49c5a6b904005256629e
Publikováno v:
Epigenetics, Vol 16, Iss 4, Pp 436-457 (2021)
Cell-fate networks are traditionally studied within the framework of gene regulatory networks. This paradigm considers only interactions of genes through expressed transcription factors and does not incorporate chromatin modification processes. This
Externí odkaz:
https://doaj.org/article/931b4a8f7e9042d495df2492cc3940f2
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103526- (2021)
Summary: A design for genetically encoded counters is proposed via repressor-based circuits. An N-bit counter reads sequences of input pulses and displays the total number of pulses, modulo 2N. The design is based on distributed computation with spec
Externí odkaz:
https://doaj.org/article/c3689ff53bb048cb885298dc6b605b48
Publikováno v:
Royal Society Open Science, Vol 8, Iss 9 (2021)
A dynamical system entrains to a periodic input if its state converges globally to an attractor with the same period. In particular, for a constant input, the state converges to a unique equilibrium point for any initial condition. We consider the pr
Externí odkaz:
https://doaj.org/article/5d60053f07a34ffc88b486b10fbfa1a6
Autor:
Anh Phong Tran, M. Ali Al-Radhawi, Irina Kareva, Junjie Wu, David J. Waxman, Eduardo D. Sontag
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Metronomic chemotherapy can drastically enhance immunogenic tumor cell death. However, the mechanisms responsible are still incompletely understood. Here, we develop a mathematical model to elucidate the underlying complex interactions between tumor
Externí odkaz:
https://doaj.org/article/2d1bb7733d7847feabc802cc3989bf58
Publikováno v:
IEEE Control Systems Letters. 7:211-216
Synthetic gene circuits require cellular resources, which are often limited. This leads to competition for resources by different genes, which alter a synthetic genetic circuit’s behavior. However, the manner in which competition impacts behavior d
Publikováno v:
IEEE Control Systems Letters. 6:578-583
Initial hopes of quickly eradicating the COVID-19 pandemic proved futile, and the goal shifted to controlling the peak of the infection, so as to minimize the load on healthcare systems. To that end, public health authorities intervened aggressively
Autor:
M. Ali Al-Radhawi
Publikováno v:
Mathematics of Control, Signals, and Systems.
Previous studies have inferred robust stability of reaction networks by utilizing linear programs or iterative algorithms. Such algorithms become tedious or computationally infeasible for large networks. In addition, they operate like black boxes wit
Autor:
M. Ali Al-Radhawi, Eduardo D. Sontag
Publikováno v:
Realization and Model Reduction of Dynamical Systems ISBN: 9783030951566
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bc830079881cd2bca4354bff17b71a0
https://doi.org/10.1007/978-3-030-95157-3_24
https://doi.org/10.1007/978-3-030-95157-3_24
The emergence of and transitions between distinct phenotypes in isogenic cells can be attributed to the intricate interplay of epigenetic marks, external signals, and gene-regulatory elements. These elements include chromatin remodelers, histone modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa12959ed6c91f2b78b1e89d682a375