Zobrazeno 1 - 10
of 96
pro vyhledávání: '"M. Albert Basson"'
Autor:
Xiuchuan (Lucas) Hu, Wenfeng Xiao, Yuxian Lei, Adam Green, Xinyi Lee, Muralidhara Rao Maradana, Yajing Gao, Xueru Xie, Rui Wang, George Chennell, M. Albert Basson, Pete Kille, Wolfgang Maret, Gavin A. Bewick, Yufeng Zhou, Christer Hogstrand
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Zinc and plant-derived ligands of the aryl hydrocarbon receptor (AHR) are dietary components affecting intestinal epithelial barrier function. Here, we explore whether zinc and the AHR pathway are linked. We show that dietary supplementation
Externí odkaz:
https://doaj.org/article/293292421854444796bd4bce0b9a0f58
Autor:
Mohi Ahmed, Ruth Moon, Ravindra Singh Prajapati, Elysia James, M. Albert Basson, Andrea Streit
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
To improve our understanding of the mechanisms that protect hair cells in the ear from stress-induced death, Ahmed et al delete the chromodomain helicase DNA-binding protein 7 (CHD7) in auditory neurons and hair cells in mice. They observe sensorineu
Externí odkaz:
https://doaj.org/article/a92fb875cfc14184bbec21667fb5460f
Autor:
Sara Badodi, Nicola Pomella, Xinyu Zhang, Gabriel Rosser, John Whittingham, Maria Victoria Niklison-Chirou, Yau Mun Lim, Sebastian Brandner, Gillian Morrison, Steven M. Pollard, Christopher D. Bennett, Steven C. Clifford, Andrew Peet, M. Albert Basson, Silvia Marino
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
BMI1 and CHD7 are chromatin remodelling genes with a role in medulloblastoma pathogenesis. Here, the authors demonstrate that the BMI1High/CHD7Low signature mediates metabolic adaptation in G4 MB and predicts response to inositol treatment either alo
Externí odkaz:
https://doaj.org/article/e099abd2067e489ba7b766a7107a8238
Autor:
Shaun Hurley, Conor Mohan, Philipp Suetterlin, Robert Ellingford, Kimberley L. H. Riegman, Jacob Ellegood, Angela Caruso, Caterina Michetti, Olivier Brock, Romy Evans, Fabrizio Rudari, Alessio Delogu, Maria Luisa Scattoni, Jason P. Lerch, Cathy Fernandes, M. Albert Basson
Publikováno v:
Molecular Autism, Vol 12, Iss 1, Pp 1-21 (2021)
Abstract Background CHD8 haploinsufficiency causes autism and macrocephaly with high penetrance in the human population. Chd8 heterozygous mice exhibit relatively subtle brain overgrowth and little gene expression changes in the embryonic neocortex.
Externí odkaz:
https://doaj.org/article/9cd56a17e41646d2b90944d9def5907e
Autor:
Sara Badodi, Adrian Dubuc, Xinyu Zhang, Gabriel Rosser, Mariane Da Cunha Jaeger, Michelle M. Kameda-Smith, Anca Sorana Morrissy, Paul Guilhamon, Philipp Suetterlin, Xiao-Nan Li, Loredana Guglielmi, Ashirwad Merve, Hamza Farooq, Mathieu Lupien, Sheila K. Singh, M. Albert Basson, Michael D. Taylor, Silvia Marino
Publikováno v:
Cell Reports, Vol 21, Iss 10, Pp 2772-2784 (2017)
Summary: We describe molecular convergence between BMI1 and CHD7 in the initiation of medulloblastoma. Identified in a functional genomic screen in mouse models, a BMI1High;CHD7Low expression signature within medulloblastoma characterizes patients wi
Externí odkaz:
https://doaj.org/article/60f4f3d022f54adf9316a3789fd48058
Autor:
Alex P. A. Donovan, Tian Yu, Jacob Ellegood, Kimberley L. H. Riegman, Christa de Geus, Conny van Ravenswaaij-Arts, Cathy Fernandes, Jason P. Lerch, M. Albert Basson
Publikováno v:
Frontiers in Neuroanatomy, Vol 11 (2017)
Reduced fibroblast growth factor (FGF) signaling from the mid-hindbrain or isthmus organizer (IsO) during early embryonic development results in hypoplasia of the midbrain and cerebellar vermis. We previously reported evidence for reduced Fgf8 expres
Externí odkaz:
https://doaj.org/article/439318cc93b44ff9878800b26030c3ec
Autor:
M. Albert Basson, Richard J. Wingate
Publikováno v:
Frontiers in Neuroanatomy, Vol 7 (2013)
Over the last sixty years, the spotlight of research has periodically returned to the cerebellum as new techniques and insights have emerged. Because of its simple homogeneous structure, limited diversity of cell types and characteristic behavioural
Externí odkaz:
https://doaj.org/article/e997e49eab4d45149a0372bb7001fa42
Autor:
Emanuela Kerschbamer, Michele Arnoldi, Takshashila Tripathi, Miguel Pellegrini, Samuele Maturi, Serkan Erdin, Elisa Salviato, Francesca Di Leva, Endre Sebestyén, Erik Dassi, Giulia Zarantonello, Matteo Benelli, Eric Campos, M Albert Basson, James F Gusella, Stefano Gustincich, Silvano Piazza, Francesca Demichelis, Michael E Talkowski, Francesco Ferrari, Marta Biagioli
Publikováno v:
Nucleic Acids Research. 50:12809-12828
Disruptive mutations in the chromodomain helicase DNA-binding protein 8 gene (CHD8) have been recurrently associated with autism spectrum disorders (ASDs). Here we investigated how chromatin reacts to CHD8 suppression by analyzing a panel of histone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7d5442c1d620440897e54d427cc892
https://doi.org/10.1093/nar/gkac1134
https://doi.org/10.1093/nar/gkac1134
Autor:
Alex P. A. Donovan, Lauren Rosko, Jacob Ellegood, Yushi Redhead, Jeremy B. A. Green, Jason P. Lerch, Jeffrey K. Huang, M. Albert Basson
Publikováno v:
Journal of Anatomy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::396c4c80711441981416526c71c812d0
https://doi.org/10.1111/joa.13856
https://doi.org/10.1111/joa.13856
Autor:
Xiuchuan Hu, Wenfeng Xiao, Yuxian Lei, Adam Green, Xinyi Lee, Muralidhara Rao Maradana, Yajing Gao, Xueru Xie, Rui Wang, George Chennell, M. Albert Basson, Pete Kille, Wolfgang Maret, Gavin A. Bewick, Yufeng Zhou, Christer Hogstrand
Both zinc and plant-derived ligands of the aryl hydrocarbon receptor (AHR) are dietary components which regulate intestinal epithelial barrier function and protect against Inflammatory Bowel Disease (IBD)1,2. Here, we explore whether zinc and AHR pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21bc3be268df5cff9668cd00548fe4cb
https://doi.org/10.1101/2022.11.03.515052
https://doi.org/10.1101/2022.11.03.515052
