Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients

Autor: M. Ahloulay, Matthew L. Albert, Charles M. Rice, Stanislas Pol, Randy S. Longman, Françoise Audat, Sandrine Fernandes, Jérémie Decalf, François Lefrerre

Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2007, 204 (10), pp.2423-2437. ⟨10.1084/jem.20070814⟩
Journal of Experimental Medicine, 2007, 204 (10), pp.2423-2437. ⟨10.1084/jem.20070814⟩

International audience; Plasmacytoid dendritic cells (pDCs) are the professional type I interferon (IFN)-producing cells, and upon activation they traffic to lymph organs, where they bridge innate and adaptive immunity. Using multianalyte profiling (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fc6c91f0a6c042f457870fce7aa31f
http://europepmc.org/articles/PMC2118448

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Direct and indirect cost of urea excretion

Autor: M. Ahloulay, Dominique Promeneur, Nadine Bouby, Lise Bankir, Marie Marcelle Trinh-Trang-Tan

Publikováno v: Kidney International. 49(6):1598-1607

Direct and indirect cost of urea excretion. Urea, the major end product of protein metabolism in mammals, is the most abundant solute in the urine. Urea excretion is thought to result from filtration curtailed by some passive reabsorbtion along the n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7b912eebe6d06f32ecccf4a7b53f42

Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV

Autor: Matthew L. Albert, M. Ahloulay, Hala Mansour, Vincent Mallet, Cyril Lababidi, Jérémie Decalf, Estelle Mottez, James Mapes, Armanda Casrouge, Arnaud Fontanet, Anaïs Vallet-Pichard, Stanislas Pol

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (1), pp.308-17. 〈10.1172/JCI40594〉
Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (1), pp.308-17. ⟨10.1172/JCI40594⟩
Journal of Clinical Investigation, 2011, 121 (1), pp.308-17. ⟨10.1172/JCI40594⟩

International audience; Chronic infection with hepatitis C virus (HCV) is a major public health problem, with nearly 170 million infected individuals worldwide. Current treatment for chronic infection is a combination of pegylated IFN-α2 and ribavir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b85bf52b527cfbc3f8ad84af20ca5e8

Extracellular cAMP inhibits proximal reabsorption: are plasma membrane cAMP receptors involved?

Autor: Lise Bankir, Peter N. Devreotes, Carole A. Parent, M. Ahloulay

Publikováno v: American journal of physiology. Renal physiology. 282(3)

Glucagon binding to hepatocytes has been known for a long time to not only stimulate intracellular cAMP accumulation but also, intriguingly, induce a significant release of liver-borne cAMP in the blood. Recent experiments have shown that the well-do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c53a62a2717e4c8b9dd53ec244e674
https://pubmed.ncbi.nlm.nih.gov/11832418