Zobrazeno 1 - 10
of 25
pro vyhledávání: '"M. Adam Meledeo"'
Autor:
Jacob B. Schriner, MD, J. Michael Van Gent, DO, M. Adam Meledeo, PhD, Scott D. Olson, PhD, Bryan A. Cotton, MD, Charles S. Cox, Jr, MD, Brijesh S. Gill, MD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 6, p e0925 (2023)
OBJECTIVES:. This narrative review article seeks to highlight the effects of citrate on physiology during massive transfusion of the bleeding patient. DATA SOURCES:. A limited library of curated articles was created using search terms including “ci
Externí odkaz:
https://doaj.org/article/4c64afc797774a33815f693d2342280d
Autor:
Philip C. Spinella, Kimberly A. Thomas, Isaiah R. Turnbull, Anja Fuchs, Kelly Bochicchio, Douglas Schuerer, Stacey Reese, Adrian A. Coleoglou Centeno, Christopher B. Horn, Jack Baty, Susan M. Shea, M. Adam Meledeo, Anthony E. Pusateri, Jerrold H. Levy, Andrew P. Cap, Grant V. Bochicchio, for the TAMPITI Investigators, M.D. Enyo Ablordeppey, M.P.H. James Fehr, M.D. Philip Miller, M.D. George Despotis, M.D. Melanie Fields, M.D. Kevin Ward
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background The hemostatic properties of tranexamic acid (TXA) are well described, but the immunological effects of TXA administration after traumatic injury have not been thoroughly examined. We hypothesized TXA would reduce monocyte activation in bl
Externí odkaz:
https://doaj.org/article/9c3d317980e541d0a813fbaa0b4592eb
Autor:
Kimberly A. Thomas, Amudan J. Srinivasan, Colby McIntosh, Katelin Rahn, Scott Kelly, Lilian McGough, Skye Clayton, Samantha Perez, Alexandra Smith, Lisa Vavro, Javonn Musgrove, Ronnie Hill, Kennedy S. Mdaki, James A. Bynum, M. Adam Meledeo, Andrew P. Cap, Philip C. Spinella, Kristin M. Reddoch‐Cardenas, Susan M. Shea
Publikováno v:
Transfusion. 63
Autor:
Kenneth W. Davis, Joshua L. Fenderson, Matthew J. Rendo, Colby S. McIntosh, Jason B. Corley, M. Adam Meledeo, Andrew P. Cap, Grantham C. Peltier
Publikováno v:
Transfusion. 59:1560-1567
Background Cryoprecipitate's shelf life is limited due to concerns over decreased clotting factor activity and contamination with extended storage. Hemostatic characteristics of thawed cryoprecipitate stored up to 35 days at refrigerated and room tem
Autor:
M. Adam Meledeo, Forest R. Sheppard, Antoni R. Macko, Ernest E. Moore, Hunter B. Moore, Andrew P. Cap
Publikováno v:
Journal of Trauma and Acute Care Surgery. 82:750-757
Hypoperfusion is associated with hyperfibrinolysis and early death from exsanguination, whereas tissue trauma is associated with hypofibrinolysis and delayed death from organ failure. We sought to elucidate the effects of injury patterns on fibrinoly
Autor:
M. Adam Meledeo, James K. Aden, Heather F. Pidcoke, Todd M. Getz, Andrew P. Cap, James A. Bynum, Armando C Rodriguez
Publikováno v:
Transfusion. 56:S76-S84
BACKGROUND Platelets (PLTs) are stored at room temperature (RT) to preserve in vivo circulation time, but PLT quality is degraded. The PLT storage lesion is mitigated by refrigeration, but questions remain regarding effects of cold storage (4°C) on
Autor:
M. Adam Meledeo, Armando C Rodriguez, Anand K. Ramasubramanian, Robbie K. Montgomery, Andrew P. Cap, Kristin M. Reddoch, Heather F. Pidcoke
Publikováno v:
Shock. 45:220-227
Refrigeration of platelets (4°C) provides the possibility of improving transfusion practice over the current standard-of-care, room temperature (RT) storage. However, the increased level of platelet activation observed at 4°C in vitro is cause for
Autor:
James A, Bynum, M Adam, Meledeo, Todd M, Getz, Armando C, Rodriguez, James K, Aden, Andrew P, Cap, Heather F, Pidcoke
Publikováno v:
Transfusion. 56
Platelets (PLTs) are stored at room temperature (RT) to preserve in vivo circulation time, but PLT quality is degraded. The PLT storage lesion is mitigated by refrigeration, but questions remain regarding effects of cold storage (4°C) on mitochondri
Publikováno v:
Carbohydrate Recognition: Biological Problems, Methods, and Applications
Autor:
Jie Fu, Christopher Weier, Benjamin C. Tang, Kevin J. Yarema, M. Adam Meledeo, Ming Yang, Srinivasa-Gopalan Sampathkumar, Sung Yun Chung, Mark B. Jones, Udayanath Aich, Justin Hanes
Publikováno v:
Glycoconjugate Journal. 27:445-459
Carbohydrates are attractive candidates for drug development because sugars are involved in many, if not most, complex human diseases including cancer, immune dysfunction, congenital disorders, and infectious diseases. Unfortunately, potential therap