Zobrazeno 1 - 10
of 367
pro vyhledávání: '"M. Abdelmoula"'
Autor:
M. Ben Jmaa, O. Abida, R. Fakhfakh, E. Bahloul, Kh. Sellami, L. Gaddour, N. Elloumi, M. Ben Ayed, A. Masmoudi, M. Dhouib, M. Abdelmoula, N. Mahfoudh, H. Makni, H. Turki, H. Masmoudi
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
Pemphigus foliaceus (PF) is a rare autoimmune skin disease caused by anti-Dsg1 pathogenic autoantibodies. It is considered as a Th2-mediated disease. Likewise, Th17 cells were recently described in the pathogenesis of the disease but their role is st
Externí odkaz:
https://doaj.org/article/cbb137f4d2de401ebd80a1c31046015f
Autor:
Walid M. Abdelmoula, Begona Gimenez-Cassina Lopez, Elizabeth C. Randall, Tina Kapur, Jann N. Sarkaria, Forest M. White, Jeffrey N. Agar, William M. Wells, Nathalie Y. R. Agar
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The high dimensional and complex nature of mass spectrometry imaging (MSI) data poses challenges to downstream analyses. Here the authors show an application of artificial intelligence in mining MSI data revealing biologically relevant metabolomic an
Externí odkaz:
https://doaj.org/article/9244c823f02b459a98d698b08982a133
Autor:
Sankha S. Basu, Sylwia A. Stopka, Walid M. Abdelmoula, Elizabeth C. Randall, Begoña Gimenez-Cassina Lopez, Michael S. Regan, David Calligaris, Fake F. Lu, Isaiah Norton, Melissa A. Mallory, Sandro Santagata, Deborah A. Dillon, Mehra Golshan, Nathalie Y. R. Agar
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Optimal resection of breast tumors requires removing cancer with a rim of normal tissue while preserving uninvolved regions of the breast. Surgical and pathological techniques that permit rapid molecular characterization of tissue could faci
Externí odkaz:
https://doaj.org/article/6971c3e8117e459bae7cdcea6a03c082
Autor:
Sylwia A Stopka, Jiska van der Reest, Walid M Abdelmoula, Daniela F Ruiz, Shakchhi Joshi, Alison E Ringel, Marcia C Haigis, Nathalie Y R Agar
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0261803 (2022)
Cells adapt their metabolism to physiological stimuli, and metabolic heterogeneity exists between cell types, within tissues, and subcellular compartments. The liver plays an essential role in maintaining whole-body metabolic homeostasis and is struc
Externí odkaz:
https://doaj.org/article/772f2e7b0d07429f94b5a4d7f25087e5
Autor:
Elizabeth C. Randall, Kristina B. Emdal, Janice K. Laramy, Minjee Kim, Alison Roos, David Calligaris, Michael S. Regan, Shiv K. Gupta, Ann C. Mladek, Brett L. Carlson, Aaron J. Johnson, Fa-Ke Lu, X. Sunney Xie, Brian A. Joughin, Raven J. Reddy, Sen Peng, Walid M. Abdelmoula, Pamela R. Jackson, Aarti Kolluri, Katherine A. Kellersberger, Jeffrey N. Agar, Douglas A. Lauffenburger, Kristin R. Swanson, Nhan L. Tran, William F. Elmquist, Forest M. White, Jann N. Sarkaria, Nathalie Y. R. Agar
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Despite major drug discovery efforts, the therapeutic options for glioblastoma (GBM) remain inadequate. Here they analyze patient-derived xenograft model of GBM to quantitatively map distribution and cellular response to the EGFR inhibitor erlotinib,
Externí odkaz:
https://doaj.org/article/17219987055045cbbd74e20d4356a523
Autor:
Nathalie Y.R. Agar, Jann N. Sarkaria, Forest M. White, William F. Elmquist, Nhan L. Tran, Jeffrey N. Agar, Marcia C. Haigis, Haejin Yoon, Sandro Santagata, Sankha S. Basu, Walid M. Abdelmoula, Michael S. Regan, Sen Peng, Begoña G.C. Lopez, Elizabeth C. Randall
Heatmap of mRNA sequencing data, highlighting the activated genes within pathways for glycolysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec4ac3c1a25630a9b6272798dfc6aec
https://doi.org/10.1158/0008-5472.22424722.v1
https://doi.org/10.1158/0008-5472.22424722.v1
Autor:
Nathalie Y.R. Agar, Jann N. Sarkaria, Forest M. White, William F. Elmquist, Nhan L. Tran, Jeffrey N. Agar, Marcia C. Haigis, Haejin Yoon, Sandro Santagata, Sankha S. Basu, Walid M. Abdelmoula, Michael S. Regan, Sen Peng, Begoña G.C. Lopez, Elizabeth C. Randall
Glioblastoma (GBM) is increasingly recognized as a disease involving dysfunctional cellular metabolism. GBMs are known to be complex heterogeneous systems containing multiple distinct cell populations and are supported by an aberrant network of blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d8cc9e0b4bcc12f4c9a655a7f9d4396
https://doi.org/10.1158/0008-5472.c.6511855.v1
https://doi.org/10.1158/0008-5472.c.6511855.v1
Autor:
Nathalie Y.R. Agar, Jann N. Sarkaria, Forest M. White, William F. Elmquist, Nhan L. Tran, Jeffrey N. Agar, Marcia C. Haigis, Haejin Yoon, Sandro Santagata, Sankha S. Basu, Walid M. Abdelmoula, Michael S. Regan, Sen Peng, Begoña G.C. Lopez, Elizabeth C. Randall
Heatmap of mRNA sequencing data, highlighting the activated genes within pathways for fatty acid metabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50814cd38c71005c9cbcca89250a65b2
https://doi.org/10.1158/0008-5472.22424725.v1
https://doi.org/10.1158/0008-5472.22424725.v1
Autor:
Nathalie Y.R. Agar, Jann N. Sarkaria, Forest M. White, William F. Elmquist, Nhan L. Tran, Jeffrey N. Agar, Marcia C. Haigis, Haejin Yoon, Sandro Santagata, Sankha S. Basu, Walid M. Abdelmoula, Michael S. Regan, Sen Peng, Begoña G.C. Lopez, Elizabeth C. Randall
Annotated peaklists from MALDI FT ICR MSI data, including measured m/z, possible identification according to Lipid Maps database and associated Δppm.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29eaee5645a82589104e91d2e93d5b7a
https://doi.org/10.1158/0008-5472.22424731
https://doi.org/10.1158/0008-5472.22424731
Autor:
Nathalie Y.R. Agar, Jann N. Sarkaria, Forest M. White, William F. Elmquist, Nhan L. Tran, Jeffrey N. Agar, Marcia C. Haigis, Haejin Yoon, Sandro Santagata, Sankha S. Basu, Walid M. Abdelmoula, Michael S. Regan, Sen Peng, Begoña G.C. Lopez, Elizabeth C. Randall
Supplementary results, Supplementary figures S1-S9 and Supplementary methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c8dfc9f31bd9dc8febc4a48c77e0b4
https://doi.org/10.1158/0008-5472.22424716
https://doi.org/10.1158/0008-5472.22424716