Zobrazeno 1 - 10
of 239
pro vyhledávání: '"M. AMHERDT"'
Autor:
M Ravazzola, M Amherdt, F. Lottspeich, J B Helms, Felix T. Wieland, Martina Bremser, K Sohn, Klaus Fiedler, L. Orci
Publikováno v:
The Journal of Cell Biology
Formation of non-clathrin-coated vesicles requires the recruitment of several cytosolic factors to the Golgi membrane. To identify membrane proteins involved in this budding process, a highly abundant type I transmembrane protein (p23) was isolated f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c98862d5194b7ca31be85e182e9cb5
https://doi.org/10.1083/jcb.135.5.1239
https://doi.org/10.1083/jcb.135.5.1239
Autor:
Julia F. Clark, C Rulka, O Weiss, Paul A. Randazzo, Richard A. Kahn, M Amherdt, James E. Rothman, T Serafini, L Orci, Peter P. Roller
Publikováno v:
Journal of Biological Chemistry. 267:13039-13046
Deletion of the amino-terminal 17 residues from human ADP-ribosylation factor (ARF) resulted in a protein ([delta 1-17]mARF1p) devoid of ARF activity but which retained the ability to bind guanine nucleotides with high affinity. Unlike the wild type,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c435127ef73b901411b7efbe572076d8
https://doi.org/10.1016/s0021-9258(18)42378-2
https://doi.org/10.1016/s0021-9258(18)42378-2
Autor:
R. G. Peterson, D. Baetens, Roger H Unger, Lelio Orci, Mariella Ravazzola, Christopher B. Newgard, John H. Johnson, M. Amherdt, Lindsey Inman
Publikováno v:
Proceedings of the National Academy of Sciences. 87:9953-9957
Non-insulin-dependent diabetes mellitus (NIDDM) is attributed to a failure of pancreatic beta cells to maintain insulin secretion at a level sufficient to compensate for underlying insulin resistance. In the ZDF rat, a model of NIDDM that closely res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a3c51d88414fb5678f98ccc8f30d5d
https://doi.org/10.1073/pnas.87.24.9953
https://doi.org/10.1073/pnas.87.24.9953
Autor:
R A, Kahn, P, Randazzo, T, Serafini, O, Weiss, C, Rulka, J, Clark, M, Amherdt, P, Roller, L, Orci, J E, Rothman
Publikováno v:
The Journal of biological chemistry. 267(18)
Deletion of the amino-terminal 17 residues from human ADP-ribosylation factor (ARF) resulted in a protein ([delta 1-17]mARF1p) devoid of ARF activity but which retained the ability to bind guanine nucleotides with high affinity. Unlike the wild type,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a582d9712edfd9cd0e73dccbb518e9d
https://pubmed.ncbi.nlm.nih.gov/1618801
https://pubmed.ncbi.nlm.nih.gov/1618801
Publikováno v:
Journal of Urology; Oct2003 Part 1, Vol. 170 Issue 4, p1409, 6p
Autor:
M. Amherdt, Lelio Orci, Jean-Dominique Vassalli, Alain Perrelet, M Ravazzola, Ole D. Madsen, Richard G.W. Anderson
Publikováno v:
The Journal of Cell Biology
The Journal of Cell Biology, Vol. 103, No 6 Pt 1 (1986) pp. 2273-2281
The Journal of Cell Biology, Vol. 103, No 6 Pt 1 (1986) pp. 2273-2281
Proinsulin is a single polypeptide chain composed of the B and A subunits of insulin joined by the C-peptide region. Proinsulin is converted to insulin during the maturation of secretory vesicles by the action of two proteases and conversion is inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd574c559a18913382534cae4ed5682
https://doi.org/10.1083/jcb.103.6.2273
https://doi.org/10.1083/jcb.103.6.2273
Publikováno v:
Journal of Clinical Investigation. 75:1249-1255
In this study we have characterized the effects of cysteamine (CHS) on the cellular content and release of immunoreactive somatostatin (S-14 LI), insulin (IRI), and glucagon (IRG) from monolayer cultures of neonatal rat islets. Incubation of cultures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f67307cb434c62a7baa3314614e1211
https://doi.org/10.1172/jci111823
https://doi.org/10.1172/jci111823
Autor:
M Ravazzola, Jean-Dominique Vassalli, Alain Perrelet, Philippe A. Halban, Lelio Orci, M. Amherdt
Publikováno v:
The Journal of Cell Biology
The Journal of Cell Biology, Vol. 99, No 6 (1984) pp. 2187-2192
The Journal of Cell Biology, Vol. 99, No 6 (1984) pp. 2187-2192
The secretion of insulin by the pancreatic B-cell involves a passage of the newly synthetized (pro)insulin polypeptides across the Golgi apparatus, at the trans pole of which secretory proteins are released as a population of secretory granules chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c5c21447df1327fc558de4791a706c
https://doi.org/10.1083/jcb.99.6.2187
https://doi.org/10.1083/jcb.99.6.2187
Autor:
A. Gutzeit, W. Stauffacher, M. Amherdt, Mariella Ravazzola, F. Malaisse-Lagae, Willy Malaisse, Lelio Orci
Publikováno v:
Diabetologia. 11:71-76
The pancreatic B-cell contains microtubules, which are thought to participate in the process of insulin release. In order to disclose a possible abnormaltiy of this B-cell microtubular system in animals with islet dysfunction, isolated islets from no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01221a499915dc1e8e754a3fb437e329
https://doi.org/10.1007/bf00422821
https://doi.org/10.1007/bf00422821
Publikováno v:
The Journal of Cell Biology
The formation of parathyroid hormone (PTH) in the parathyroid gland occurs via two successive proteolytic cleavages from larger biosynthetic precursors. The initial product coded for by PTH mRNA is pre-proparathyroid hormone (PreProPTH), a polypeptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe008b3a06dda48aeca616094abe6f6
https://doi.org/10.1083/jcb.80.3.715
https://doi.org/10.1083/jcb.80.3.715