Zobrazeno 1 - 10
of 25
pro vyhledávání: '"M. A. Taipov"'
Publikováno v:
Опухоли женской репродуктивной системы, Vol 11, Iss 2, Pp 8-18 (2015)
Breast malignancies hold the lead in the pattern of cancers among women worldwide. Currently used methods for the instrumental diagnosis of breast cancer (BC) and their related diagnostic procedures are not sophisticated. The common constraint of ins
Externí odkaz:
https://doaj.org/article/7b17eeed209648babf3fdc6baf262981
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 3, Pp 8-13 (2014)
Identification of markers that will identify the disease at an early preclinical stage, is the main goal of our research. Diagnostic marker should have the following characteristics: high sensitivity and specificity, be readily accessible for the ana
Externí odkaz:
https://doaj.org/article/fde0843a498547dabf2903f4b02074af
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 1, Pp 8-14 (2014)
The expression of СOX-2, VEGF, VEGFR-1, VEGFR-2, VEGFR-3, EGFR, endoglin (СD105), and IL-6 was analyzed in the human breast tumor cells having a varying metastatic potential. The role of these factors in the regulation of the metastatic potential o
Externí odkaz:
https://doaj.org/article/7b9639f9facc474699651d72d2cd6ab9
Autor:
V. E. Shevchenko, M. A. Taipov, S. V. Kovalev, N. E. Arnotskaya, O. M. Pavlova, I. A. Kudryavtsev, Z. N. Nikiforova
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 3-4, Pp 19-28 (2014)
The proteome of lysates of the breast tumor cell lines MCF-7, BT-474, and ZR-75-1 was mapped, resulting in the sequence of 340 proteins. The proteins associated with the biosynthesis of PGE2 and with the regulation of cyclooxygenase-2 expression were
Externí odkaz:
https://doaj.org/article/2c37c8b863e74eb88f93c0677d76d243
Autor:
V. E. Shevchenko, M. A. Taipov, S. V. Kovalev, N. E. Arnotskaya, O. M. Pavlova, I. A. Kudryavtsev, Z. N. Nikiforova
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 2, Pp 4-10 (2014)
Mass spectrometric mapping of proteomic lysate of a MCF-7 cancer cell line was carried out, which identified 153 proteins having molecular weights of 5000 to 630000 Da, a high proportion of which was cytoplasmic and nuclear proteins. The latter accou
Externí odkaz:
https://doaj.org/article/2843f70f632b4c52b0ac271e7ea0f673
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 3-4, Pp 6-11 (2014)
In the cell there is a large class of regulatory molecules referred to as microRNA. Many investigators regard microRNA Mir and Mir-155 as new potential prognostic markers and targets for goal-oriented therapy for breast cancer (BC) these days. MiR-21
Externí odkaz:
https://doaj.org/article/510fa0c0f5eb4e5897cc8b70f7b2a3c4
Autor:
M. A. Taipov, Z. N. Nikiforova, O. M. Pavlova, I. A. Kudryavtsev, N. Ye. Arnotskaya, V. Ye. Shevchenko
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 2, Pp 16-22 (2014)
This paper analyzes 15-PGDH gene expression in the human breast cancer (BC) cell liness and describes the molecular principles through which the expression of the enzyme 15-PGDH is controlled in the tumor cells with a varying metastatic potential. Th
Externí odkaz:
https://doaj.org/article/49f49b51047549a08734e93a9df53120
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 3-4, Pp 12-17 (2014)
Current therapeutic approaches based on a study of the genetic portrait of a tumor individualize treatment policy to a greater extent, which cre- ates real prospects for the increasing number of patients to recover. Experimental and clinical evidence
Externí odkaz:
https://doaj.org/article/c4e0f4edff8640d1b8f4db9a0f4f754a
Autor:
M. A. Taipov, Z. N. Nikiforova, O. M. Pavlova, I. A. Kudryavtsev, N. Ye. Arnotskaya, V. Ye. Shevchenko
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 1-2, Pp 6-12 (2014)
The expression of the SMAD2, SMAD4, SMAD7, and СOX-2 genes and the levels of Smad4, phosphorylated Smad2, and Smad7 proteins were analyzed in the human breast cancer (BC) cell lines MCF-7, BT-474, and ZR-75-1. The SMAD2 and SMAD4 genes were found to
Externí odkaz:
https://doaj.org/article/c98ca73b0720479eb0a96d9ba11d1b63
Publikováno v:
Опухоли женской репродуктивной системы, Vol 0, Iss 3-4, Pp 86-89 (2014)
Currently, basic research in oncology focused on finding new potential markers of metastatic activity of tumor cells and rational approaches to cancer therapy. Constant search for biomarkers of endometrial cancer with high sensitivity and specificity
Externí odkaz:
https://doaj.org/article/eb0b168bbbd842dba3df523592d96201