Zobrazeno 1 - 10
of 37
pro vyhledávání: '"M. A. Schwaller"'
Publikováno v:
Biospectroscopy. 2:377-389
The bioxidative transformation of the antitumor drug N(2)-methyl-9-hydroxy ellipticinium (NMHE) by the peroxidase-H2O2 system leads to a highly electrophilic quinoneimine species. This species may react with biological macromolecules such as proteins
Publikováno v:
Journal of Raman Spectroscopy. 27:539-547
Oxidative transformations of 9-hydroxyellipticine (9-OH-E) andN2-methyl-9-hydroxyellipticinium (NMHE) were performed in aqueous solutions. Electrochemical oxidation of 9-OH-E and biochemical and chemical oxidation of NMHE, were monitored by UV–visi
Publikováno v:
Journal of Biological Chemistry. 270:22709-22713
Ellipticine is an antitumor alkaloid capable of uncoupling mitochondrial oxidative phosphorylation. It behaves as a lipophilic weak base with pK = 7.40. We have investigated its molecular mode of action using several of its isomers with pK ranging be
Publikováno v:
ChemInform. 24
Publikováno v:
ChemInform. 24
Spectroscopic, thermodynamic, and kinetic results have allowed the characterization of two aggregation modes in the alkyl-substituted oxazolopyridocarbazole (OPC) series. Short-chain substituted derivatives (H-, methyl-, ethyl-, and propyl-OPCs) self
Publikováno v:
The Journal of Physical Chemistry. 96:8785-8791
Spectroscopic, thermodynamic, and kinetic results have allowed the characterization of two aggregation modes in the alkyl-substituted oxazolopyridocarbazole (OPC) series. Short-chain substituted derivatives (H-, methyl-, ethyl-, and propyl-OPCs) self
Publikováno v:
Journal of Raman Spectroscopy. 23:373-377
Surface-enhanced Raman spectroscopy (SERS) in silver colloidal solutions of ellipticine, 2-N-methylellipticinium and their complexes with DNA were investigated. On varying the pH of silver sols, large spectral changes are observed in the SER spectra
Publikováno v:
Biopolymers. 31:519-527
Viscosimetric and kinetic results allow one to characterize three modes of DNA binding in the ellipticine series: (1) Ellipticine and its 9 methoxy derivative, which present maximal DNA lengthening properties and bind DNA through a single step mechan
Publikováno v:
Journal of Luminescence. :419-424
The in vivo accessibility of ellipticine to its different intracellular targets in isolated living K562 leukemia cells, has been studied by means of a microspectrofluorometric technique. Fluorescence emission spectra from selected microvolumes in cyt
Autor:
G. Dodin, Georg Ole Sørensen, O.Faurskvo Nielsen, Daniel H. Christensen, M. A. Schwaller, Jean Aubard, J.M. Espinosa
Publikováno v:
Spectrochimica Acta Part A: Molecular Spectroscopy. 47:1423-1429
Nucleotides and nucleosides have been studied in the low-frequency region through a comparison of the performance between near-infrared Fourier transform Raman techniques and Ar + -excitation Raman spectroscopy. This allowed us to evaluate the influe