Zobrazeno 1 - 10
of 122
pro vyhledávání: '"M. A. Rowley"'
Autor:
Sreyashi Bhattacharya, Hannah L. Harris, Ridwan Islam, Sanika Bodas, Navatha Polavaram, Juhi Mishra, Dipanwita Das, Parthasarathy Seshacharyulu, Achyuth Kalluchi, Anirban Pal, Manish Kohli, Subodh M. Lele, Michael Muders, Surinder K. Batra, Paramita M. Ghosh, Kaustubh Datta, M. Jordan Rowley, Samikshan Dutta
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-18 (2024)
Abstract Resistance to the current Androgen Receptor Signaling Inhibitor (ARSI) therapies has led to higher incidences of therapy-induced neuroendocrine-like prostate cancer (t-NEPC). This highly aggressive subtype with predominant small-cell-like ch
Externí odkaz:
https://doaj.org/article/2b98ea921a8d460aa22a9de1beae8f05
Autor:
Aaqib M. Bhat, Bhopal C. Mohapatra, Haitao Luan, Insha Mushtaq, Sukanya Chakraborty, Siddhartha Kumar, Wangbin Wu, Ben Nolan, Samikshan Dutta, Matthew D. Storck, Micah Schott, Jane L. Meza, Subodh M. Lele, Ming-Fong Lin, Leah M. Cook, Eva Corey, Colm Morrissey, Donald W. Coulter, M. Jordan Rowley, Amarnath Natarajan, Kaustubh Datta, Vimla Band, Hamid Band
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract While better management of loco-regional prostate cancer (PC) has greatly improved survival, advanced PC remains a major cause of cancer deaths. Identification of novel targetable pathways that contribute to tumor progression in PC could ope
Externí odkaz:
https://doaj.org/article/5e1271695c79456bb92777ad45c70f97
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Transcription reprogramming during cell differentiation involves targeting enhancers to genes responsible for establishment of cell fates. To understand the contribution of CTCF-mediated chromatin organization to cell lineage commitment, we
Externí odkaz:
https://doaj.org/article/00e0a254d49a49f2932ed23a536029a6
Autor:
Sukanya Chakraborty, Aaqib M. Bhat, Insha Mushtaq, Haitao Luan, Achyuth Kalluchi, Sameer Mirza, Matthew D. Storck, Nagendra Chaturvedi, Jose Antonio Lopez-Guerrero, Antonio Llombart-Bosch, Isidro Machado, Katia Scotlandi, Jane L. Meza, Gargi Ghosal, Donald W. Coulter, M. Jordan Rowley, Vimla Band, Bhopal C. Mohapatra, Hamid Band
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-21 (2023)
Abstract Overexpression of the EPS15 Homology Domain containing 1 (EHD1) protein has been linked to tumorigenesis but whether its core function as a regulator of intracellular traffic of cell surface receptors plays a role in oncogenesis remains unkn
Externí odkaz:
https://doaj.org/article/09e76c7a25c7457f98d7a6fdc6e884ba
Autor:
Hannah L. Harris, Huiya Gu, Moshe Olshansky, Ailun Wang, Irene Farabella, Yossi Eliaz, Achyuth Kalluchi, Akshay Krishna, Mozes Jacobs, Gesine Cauer, Melanie Pham, Suhas S. P. Rao, Olga Dudchenko, Arina Omer, Kiana Mohajeri, Sungjae Kim, Michael H. Nichols, Eric S. Davis, Dimos Gkountaroulis, Devika Udupa, Aviva Presser Aiden, Victor G. Corces, Douglas H. Phanstiel, William Stafford Noble, Guy Nir, Michele Di Pierro, Jeong-Sun Seo, Michael E. Talkowski, Erez Lieberman Aiden, M. Jordan Rowley
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Nuclear compartments are prominent features of 3D chromatin organization, but sequencing depth limitations have impeded investigation at ultra fine-scale. CTCF loops are generally studied at a finer scale, but the impact of looping on proxim
Externí odkaz:
https://doaj.org/article/273c83ceac55444f8d76b4044e6d0017
Autor:
Devin Rocks, Mamta Shukla, Laila Ouldibbat, Silvia C. Finnemann, Achyuth Kalluchi, M. Jordan Rowley, Marija Kundakovic
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Here the authors provide evidence that 3D chromatin structure in the mouse brain differs between males and females and undergoes dynamic remodelling during the female ovarian cycle. They show female-specific 3D genome dynamics affects neuronal gene e
Externí odkaz:
https://doaj.org/article/202b6f36f95a42a1a01547b4b2b59f11
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Genomes are organized into nuclear compartments, separating active from inactive chromatin. Chromatin compartments are readily visible in a large number of species by experiments that map chromatin conformation genome-wide. When analyzing these maps,
Externí odkaz:
https://doaj.org/article/7d702eb639e6489aad3217c00b955d54
Autor:
Irene Gutierrez-Perez, M. Jordan Rowley, Xiaowen Lyu, Viviana Valadez-Graham, Diana M. Vallejo, Esther Ballesta-Illan, Jose P. Lopez-Atalaya, Isaac Kremsky, Esther Caparros, Victor G. Corces, Maria Dominguez
Publikováno v:
Cell Reports, Vol 28, Iss 10, Pp 2715-2727.e5 (2019)
Summary: Evidence suggests that Polycomb (Pc) is present at chromatin loop anchors in Drosophila. Pc is recruited to DNA through interactions with the GAGA binding factors GAF and Pipsqueak (Psq). Using HiChIP in Drosophila cells, we find that the ps
Externí odkaz:
https://doaj.org/article/b1134bcf5a3d40e694e695a94bf900ba
Autor:
M. Jordan Rowley, Xiaowen Lyu, Vibhuti Rana, Masami Ando-Kuri, Rachael Karns, Giovanni Bosco, Victor G. Corces
Publikováno v:
Cell Reports, Vol 26, Iss 11, Pp 2890-2903.e3 (2019)
Summary: Interaction domains in Drosophila chromosomes form by segregation of active and inactive chromatin in the absence of CTCF loops, but the role of transcription versus other architectural proteins in chromatin organization is unclear. Here, we
Externí odkaz:
https://doaj.org/article/48a3af521a85462f855f4f5f92bf84d5
Autor:
Aaqib M. Bhat, Bhopal C. Mohapatra, Haitao Luan, Insha Mushtaq, Sukanya Chakraborty, Samikshan Dutta, Matthew D. Storck, Jane L. Meza, Subodh Lele, Ming-Fong Lin, Leah M. Cook, Eva Corey, Colm Morrissey, Donald W. Coulter, M. Jordan Rowley, Kaustubh Datta, Vimla Band, Hamid Band
Publikováno v:
bioRxiv
While better management of loco-regional prostate cancer (PC) has greatly improved survival, advanced PC remains a major cause of cancer deaths. Identification of novel, targetable, pathways that contribute to tumor progression of PC could open new t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1318a72725b892ee03028def6af5575c
https://doi.org/10.1101/2023.03.18.533299
https://doi.org/10.1101/2023.03.18.533299