Zobrazeno 1 - 10 of 128 pro vyhledávání: '"M. A. Packham"'
1
FOCAL AORTIC INJURY CAUSED BY CANNULATION: INCREASED PLASMA PROTEIN ACCUMULATION AND THROMBOSIS
Autor: J F Mustard, H. C. Rowsell, Michael R. Buchanan, Leif Jørgensen, M. A. Packham
Publikováno v: Acta Pathologica Microbiologica Scandinavica Section A Pathology. :637-647
Previous studies have shown evidence of “spontaneous” injury associated with increased permeability in focal areas of non-atherosclerotic animal aortas. In this study, a mild intimal injury was induced by brief cannulation of the thoracic aorta o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05e7493ec5eea99d191f6351ea7fcce
https://doi.org/10.1111/j.1699-0463.1974.tb03588.x
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3
Inositol phospholipid metabolism in human platelets stimulated by ADP
Autor: J D Vickers, Raelene L. Kinlough-Rathbone, J F Mustard, M A Packham
Publikováno v: European Journal of Biochemistry. 193:521-528
ADP-induced changes in inositol phospholipids, phosphatidic acid and inositol phosphates of human platelets have been studied in detail, using not only 32P labelling, but also by examining changes in amounts of the phospholipids, their labelling with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21da4534c40bac6cf0a6e2bf828dee56
https://doi.org/10.1111/j.1432-1033.1990.tb19367.x
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4
The fibrinogen gamma chain dodecapeptide inhibits agonist-induced aggregation of rabbit platelets and fibrinogen binding to rabbit glycoprotein IIb-IIIa
Autor: M L, Rand, M A, Packham, D M, Taylor, E L, Yeo, C H, Gemmell, S, Patil, S C, Lam
Publikováno v: Thrombosis and haemostasis. 82(6)
The HHLGGAKQAGDV (H12) sequence at the carboxyl termini of the y chains and the RGD sequences in the Aalpha chains of human fibrinogen are potential recognition sites for the binding of soluble fibrinogen to glycoprotein IIb-IIIa (GPIIb-IIIa) on acti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8b9cc8e346c1d8bc433544cb53b6120e
https://pubmed.ncbi.nlm.nih.gov/10613655
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6
Ethanol inhibits thrombin-induced secretion of the contents of human platelet dense and alpha-granules and lysosomes
Autor: A, Nguyen, C H, Gemmell, E L, Yeo, M A, Packham, M L, Rand
Publikováno v: Thrombosis and haemostasis. 80(4)
Moderate consumption of alcoholic beverages is associated with a reduction in thromboembolic complications of coronary artery disease, possibly partially attributable to inhibition by ethanol of platelet responses to some aggregating agents. Although
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c5bdc030387cbb3bbde963fa21378297
https://pubmed.ncbi.nlm.nih.gov/9798988
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7
Pretreatment of human platelets with plasmin inhibits responses to thrombin, but potentiates responses to low concentrations of aggregating agents, including the thrombin receptor activating peptide, SFLLRN
Autor: R L, Kinlough-Rathbone, D W, Perry, M L, Rand, M A, Packham
Publikováno v: Thrombosis and haemostasis. 77(4)
Effects of plasmin on platelets, that influence subsequent responses to aggregating agents, are relevant to attempts to prevent rethrombosis following administration of fibrinolytic agents. We describe plasmin-induced inhibition of platelet responses
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::46f56271ab41bc5a5c17447742f0c9bf
https://pubmed.ncbi.nlm.nih.gov/9134653
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8
Differences between platelet phosphoinositide metabolism stimulated by thrombin or SFLLRN are not accounted for by interaction of thrombin with glycoprotein Ib
Autor: J D, Vickers, M A, Packham, R L, Kinlough-Rathbone
Publikováno v: American journal of hematology. 54(4)
The formation of inositol phosphates was compared in aspirin-treated, washed human platelets suspended in Tyrode's-albumin solution containing 2 mM calcium and stimulated with SFLLRN (thrombin receptor-activating peptide) or thrombin. SFLLRN (20 micr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5b06eee6aa5c8f661cc0eff9311ac6f1
https://pubmed.ncbi.nlm.nih.gov/9092683
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9
Probenecid inhibits platelet responses to aggregating agents in vitro and has a synergistic inhibitory effect with penicillin G
Autor: M A, Packham, M L, Rand, D W, Perry, D H, Ruben, R L, Kinlough-Rathbone
Publikováno v: Thrombosis and haemostasis. 76(2)
Probenecid is an anion channel blocker and uricosuric agent, originally developed to slow the rate of excretion of penicillin. It is now also administered with many other drugs to reduce their required dosages. Recently, probenecid (2.5 mM) has been
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5abee86502ac22b60a37490e53a72ec8
https://pubmed.ncbi.nlm.nih.gov/8865538
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10
Conditions influencing release of granule contents from human platelets in citrated plasma induced by ADP or the thrombin receptor activating peptide SFLLRN: direct measurement of percent release of beta-thromboglobulin and assessment by flow cytometry of P-selectin expression
Autor: M L, Rand, D W, Perry, M A, Packham, C H, Gemmell, E L, Yeo, R L, Kinlough-Rathbone
Publikováno v: American journal of hematology. 52(4)
Contrary to a recent report [Rinder et al.: Blood 82:505, 1993], aspirin does inhibit the release of alpha-granule contents as well as inhibiting the release of dense granule contents by human platelets during ADP-induced aggregation in citrated plat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bace0d574e3428d0096972b1f1daf343
https://pubmed.ncbi.nlm.nih.gov/8701947
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