Výsledky vyhledávání - "M. A. Pacciarini"

Spatiotemporal and Ecological Patterns ofMycobacterium microtiInfection in Wild Boar (Sus scrofa)

Autor: L. Alborali, Nicola Ferrari, Maria Beatrice Boniotti, Dominga Avisani, Mario Chiari, Mariagrazia Zanoni, Daniele Giardiello, M. L. Pacciarini

Publikováno v: Transboundary and Emerging Diseases. 63:e381-e388

Summary Mycobacterium microti has recently been described as the causative agent of tuberculosis-like lesions in wild boar (Sus scrofa), a reservoir specie of Mycobacterium tuberculosis complex (MTBC) in some European Mediterranean ecosystem. Through

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23c332adb6d128f9e4f936f6552ed61
https://doi.org/10.1111/tbed.12313

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A first in man, phase I dose-escalation study of PHA-793887, an inhibitor of multiple cyclin-dependent kinases (CDK2, 1 and 4) reveals unexpected hepatotoxicity in patients with solid tumors

Autor: Angela Scaburri, Cinzia Pellizzoni, Guido Kroemer, Bernard Laffranchi, Rastilav Balheda, Christophe Massard, Jean-Charles Soria, Chris Twelves, Jean-Pierre Armand, M. A. Pacciarini, A Proctor, D. Alan Anthoney

Publikováno v: Cell Cycle. 10:963-970

PHA-793887 is an inhibitor of multiple cyclin dependent kinases (CDK) with activity against CDK2, CDK1 and CDK4. The primary objectives of this first in man study were to determine the dose limiting toxicities (DLTs), maximum tolerated dose (MTD) and

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https://doi.org/10.4161/cc.10.6.15075

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Molecular Typing of Mycobacterium bovis Strains Isolated in Italy from 2000 to 2006 and Evaluation of Variable-Number Tandem Repeats for Geographically Optimized Genotyping

Autor: M. Beatrice Boniotti, Alessandro Benedetto, Annalisa Garrone, Maria Goria, Alessandro Dondo, Daniela Loda, Alessandra Mondo, Simona Zoppi, Silvia Tagliabue, Stefano Bonora, Mariagrazia Zanoni, Giorgio Zanardi, M. Lodovica Pacciarini, Ernesto Tisato

Publikováno v: Journal of Clinical Microbiology. 47:636-644

Spoligotyping and exact tandem repeat (ETR) analysis of Mycobacterium bovis and M. caprae isolated strains has been routinely carried out in Italy since 2000 to obtain a database of genetic profiles and support traditional epidemiological investigati

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https://doi.org/10.1128/jcm.01192-08

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Mycobacterium porcinum strains isolated from bovine bulk milk: Implications for Mycobacterium avium subsp. paratuberculosis detection by PCR and culture

Autor: G. L. Belletti, M. L. Pacciarini, Norma Arrigoni, R. Taddei, Ilaria Barbieri, F. Fallacara

Publikováno v: Veterinary Microbiology. 130:338-347

In this study, the isolation of 52 mycobactin-independent fast growing mycobacteria from 631 bulk milk samples (8.2%), is reported. These strains, isolated during a bulk milk survey for Mycobacterium avium subsp. paratuberculosis (Map), strongly affe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ff6f8156963fd18bd18014af211a71
https://doi.org/10.1016/j.vetmic.2008.02.007

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Genomic and antigenic characterization of viruses from the 1993 Italian foot-and-mouth disease outbreak

Autor: Belén Borrego, Francisco Sobrino, Emiliana Brocchi, M. L. Pacciarini, P. Fusi, José I. Núñez

Publikováno v: Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
INIA: Repositorio de Resultados de Investigación del INIA

The origin and evolution of the type O foot-and-mouth disease viruses (FMDV) that caused the outbreak occurrence in Italy in 1993, the first episode of the disease in the EU after adoption of a non-vaccination policy in 1991, have been studied by the

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https://doi.org/10.1007/s00705-005-0585-y

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THE EFFECT OF FOOD ON CABERGOLINE PHARMACOKINETICS AND TOLERABILITY IN HEALTHY VOLUNTEERS

Autor: Margherita Strolin-Benedetti, M. Rocchetti, Steve Toon, Beverly I Holt, S. Persiani, M. A. Pacciarini

Publikováno v: Biopharmaceutics & Drug Disposition. 17:443-455

The effect of food on the pharmacokinetics and tolerability of cabergoline in man was investigated. For this purpose an open, randomized, single-dose study was conducted in 12 healthy male volunteers who received 1 mg cabergoline as tablets both unde

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https://doi.org/10.1002/(sici)1099-081x(199607)17:5<443::aid-bdd443>3.0.co

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Phase I study of the safety, tolerability and pharmacokinetics of PHA-848125AC, a dual tropomyosin receptor kinase A and cyclin-dependent kinase inhibitor, in patients with advanced solid malignancies

Autor: Antonio Jimeno, Angela Scaburri, Ramesh K. Ramanathan, Lisa Blaydorn, Marina Ciomei, Glen J. Weiss, Raoul Tibes, Mitesh J. Borad, Daniel D. Von Hoff, M. A. Pacciarini, Gayle S. Jameson, Manuel Hidalgo, Francesco Fiorentini, Daniel A. Laheru, Jeffrey D. Isaacs

Purpose This phase I trial assessed the safety, maximally tolerated dose (MTD) and pharmacokinetics of TRKA/CDK inhibitor PHA-848125AC in adult patients with advanced/metastatic solid tumors. Patients and methods Patients with relapsed or refractory

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https://europepmc.org/articles/PMC3561458/

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Detection and identification of Leptospira interrogans serovars by PCR coupled with restriction endonuclease analysis of amplified DNA

Autor: P Fusi, M L Pacciarini, C Rossi, S Tagliabue, M L Savio

Publikováno v: Scopus-Elsevier

Primers for PCR were selected from a sequenced fragment of clone pL590, which contains a repetitive element present in the genome of Leptospira interrogans serovar hardjo type hardjoprajitno (M. L. Pacciarini, M. L. Savio, S. Tagliabue, and C. Rossi,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21520dbb765dbfa198921694fe583f6
https://pubmed.ncbi.nlm.nih.gov/8027346

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