Zobrazeno 1 - 10
of 132
pro vyhledávání: '"M. A. McGee"'
Autor:
M. Ryan Haley, M. Kevin McGee
Publikováno v:
Scientometrics. 128:3337-3346
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c524a2ab30bdd9ee32ce3a0248eef459
https://doi.org/10.1007/s11192-023-04727-0
https://doi.org/10.1007/s11192-023-04727-0
Selective Anti-Leishmanial Strathclyde Minor Groove Binders Using an N-Oxide Tail-Group Modification
Autor:
Marina C. Perieteanu, Leah M. C. McGee, Craig D. Shaw, Donna S. MacMillan, Abedawn I. Khalaf, Kirsten Gillingwater, Rebecca Beveridge, Katharine C. Carter, Colin J. Suckling, Fraser J. Scott
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11912 (2022)
The neglected tropical disease leishmaniasis, caused by Leishmania spp., is becoming more problematic due to the emergence of drug-resistant strains. Therefore, new drugs to treat leishmaniasis, with novel mechanisms of action, are urgently required.
Externí odkaz:
https://doaj.org/article/dfb9f42b7d064da89f760231f1a2e658
Autor:
Charlotte Hind, Melanie Clifford, Charlotte Woolley, Jane Harmer, Leah M. C. McGee, Izaak Tyson-Hirst, Henry J. Tait, Daniel P. Brooke, Stephanie J. Dancer, Iain S. Hunter, Colin J. Suckling, Rebecca Beveridge, John A. Parkinson, J. Mark Sutton, Fraser J. Scott
Publikováno v:
ACS Infectious Diseases. 8:2552-2563
MGB-BP-3 is a potential first-in-class antibiotic, a Strathclyde Minor Groove Binder (S-MGB), that has successfully completed Phase IIa clinical trials for the treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd40ee75d50fe78bef77a7f42c5f6f2
https://doi.org/10.1021/acsinfecdis.2c00445
https://doi.org/10.1021/acsinfecdis.2c00445
Autor:
Christian Tentellino, William J. Tipping, Leah M. C. McGee, Laura M. Bain, Corinna Wetherill, Stacey Laing, Izaak Tyson-Hirst, Colin J. Suckling, Rebecca Beveridge, Fraser J. Scott, Karen Faulds, Duncan Graham
Publikováno v:
RSC Chemical Biology. 3:1403-1415
Quantitative drug imaging in live cells is a major challenge in drug discovery and development. Many drug screening techniques are performed in solution, and therefore do not consider the impact of the complex cellular environment in their result. As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1a34b9743ec9bc7293589a4af155fa
https://doi.org/10.1039/d2cb00159d
https://doi.org/10.1039/d2cb00159d
Autor:
Jennifer M. J. McGee
Publikováno v:
International Handbook of Psychology Learning and Teaching ISBN: 9783030287443
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9e170b494def5bb6a7160b7deb2276f
https://doi.org/10.1007/978-3-030-28745-0_35
https://doi.org/10.1007/978-3-030-28745-0_35
Autor:
Fraser J. Scott, Abedawn I. Khalaf, C. D. Shaw, Jasmine M. Cross, Colin J. Suckling, Kirsten Gillingwater, Craig Irving, Katharine C. Carter, Michael P. Barrett, Federica Giordani, Daniel P. Brooke, Leah M. C. McGee
Publikováno v:
RSC Medicinal Chemistry
This paper describes the design and synthesis of Strathclyde minor groove binders (S-MGBs) that have been truncated by the removal of a pyrrole ring in order to mimic the structure of the natural product, disgocidine. S-MGBs have been found to be act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf3ca14144cbb02399ebbd23d4e626a
http://europepmc.org/articles/PMC8372214
http://europepmc.org/articles/PMC8372214
Autor:
Nathan S. Kieswetter, Mumin Ozturk, Lerato Hlaka, Julius Ebua Chia, Ryan J. O. Nichol, Jasmine M. Cross, Leah M. C. McGee, Izaak Tyson-Hirst, Rebecca Beveridge, Frank Brombacher, Katharine C. Carter, Colin J. Suckling, Fraser J. Scott, Reto Guler
Publikováno v:
The Journal of antimicrobial chemotherapy. 77(4)
Background Previously, we evaluated the intracellular mycobactericidal activity of the minor groove binder, S-MGB-364 against the clinical Mycobacterium tuberculosis (Mtb) strain HN878 in macrophages. Objectives To assess the mycobactericidal activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf7fb4df418068e7ec08003901c7999
https://pubmed.ncbi.nlm.nih.gov/35084027
https://pubmed.ncbi.nlm.nih.gov/35084027
Publikováno v:
Journal of Health Care for the Poor and Underserved. 30:1184-1196
Community-based interventions such as health fairs feature diagnostic and preventive services that are useful to address health disparities in underserved stakeholders. Quantitative evaluation of these events presents challenges. This study applied t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c120cef14b8ca2bd0d77844fef517f2
https://doi.org/10.1353/hpu.2019.0081
https://doi.org/10.1353/hpu.2019.0081
Autor:
Katharine C. Carter, Michael P. Barrett, Leah M. C. McGee, Federica Giordani, Colin J. Suckling, Daniel P. Brooke, C. D. Shaw, Fraser Scott, Craig Irving, Abedawn I. Khalaf, Kirsten Gillingwater, Jasmine M. Cross
Publikováno v:
RSC Medicinal Chemistry
This paper describes the design and synthesis of Strathclyde minor groove binders (S-MGBs) that have been truncated by the removal of a pyrrole ring in order to mimic the structure of the natural product, disgocidine. S-MGBs have been found to be act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd348507ccd65886b47a705c7be99d4
https://edoc.unibas.ch/91407/
https://edoc.unibas.ch/91407/
Autor:
Ike Brannon, M. Kevin McGee
Publikováno v:
SSRN Electronic Journal.
In 2012 President Obama established Deferred Action for Childhood Arrivals, or DACA, providing legal protection for foreign nationals who arrived in the U.S. as children. In 2017 President Trump took steps to end DACA, only to be rebuffed by the cour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09460adf4f21df76e0b4d0aea603064e
https://doi.org/10.2139/ssrn.3861371
https://doi.org/10.2139/ssrn.3861371