Výsledky vyhledávání - "M. A. Mascelli"

Cleaved secretory leucocyte protease inhibitor as a biomarker of chymase activity in allergic airway disease

Autor: J. D. Boot, L. De Garavilla, Deborah A. Polkovitch, A. Batheja, Zuzana Diamant, Meghan Towers, Michael R. D'Andrea, Stanley M. Belkowski, M. A. Mascelli, Brenda M. Hertzog

Publikováno v: Clinical & Experimental Allergy. 39:1179-1186

Summary Background Secretory leucocyte protease inhibitor (SLPI), which is present in many physiological fluids including saliva, sputum and nasal discharge, is the most effective inhibitor of chymase. Previously, we demonstrated that chymase is able

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd256042e77f094b50d6067348a3707
https://doi.org/10.1111/j.1365-2222.2009.03247.x

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Original article: Nasal nitric oxide: longitudinal reproducibility and the effects of a nasal allergen challenge in patients with allergic rhinitis

Autor: M. L. De Kam, H. de Groot, M. A. Mascelli, Zuzana Diamant, R. Gerth van Wijk, A. F. Cohen, J. D. Boot, B. Miller

Publikováno v: Allergy. 62:378-384

Background: Exhaled nitric oxide (eNO) is a validated noninvasive marker of airway inflammation in asthma. In patients with allergic rhinitis (AR), increased levels of nasal nitric oxide (nNO) have also been measured. However, the applicability of nN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db1dabc48137edaba8d470912590f420
https://doi.org/10.1111/j.1398-9995.2007.01328.x

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Comparison of biomarkers between allergic rhinitis only and allergic rhinitis with concomitant asthma

Autor: R. Gerth van Wijk, Zuzana Diamant, W. Y. Wang, M. A. Mascelli, J. D. Boot

Publikováno v: Allergy, 64(7), 1102-1103. Wiley-Blackwell Publishing Ltd

This post hoc analysis suggests distinct immunologic profiles in the allergic rhinitis (AR)-only and the AR & AA phenotypes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb88777f72b145e90744908c18117829
https://pure.eur.nl/en/publications/733ffe58-6e34-431d-82d0-f83387ad8ca3

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Consequences of immunogenicity to the therapeutic monoclonal antibodies ReoPro and Remicade

Autor: C L, Wagner, A, Schantz, E, Barnathan, A, Olson, M A, Mascelli, J, Ford, L, Damaraju, T, Schaible, R N, Maini, J E, Tcheng

Publikováno v: Developments in biologicals. 112

The clinical consequences of immune antibodies generated to abciximab (ReoPro) and infliximab (Remicade) are described. Abciximab, a chimaeric Fab fragment that binds to the beta3 integrin of the GPIIb/IIIa and alphavbeta3 receptors on human platelet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0b975db48a8db812445a38c416adeaf2
https://pubmed.ncbi.nlm.nih.gov/12762503

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Effect of Ca2+ chelation on the platelet inhibitory ability of the GPIIb/IIIa antagonists abciximab, eptifibatide and tirofiban

Autor: S J, Marciniak, R E, Jordan, M A, Mascelli

Publikováno v: Thrombosis and haemostasis. 85(3)

Enhanced GPIIb/IIIa binding and inhibition of platelet aggregation of eptifibatide by the reduction of ionized plasma calcium concentrations have been reported. The present study compared the importance of Ca2+ chelation on the in vitro platelet inhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e8bdf72f6eefc3667e338f5aec135360
https://pubmed.ncbi.nlm.nih.gov/11307828

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Ticlopidine enhances the platelet inhibitory capacity of abciximab in vitro

Autor: N S, Kleiman, N, Graziadei, R E, Jordan, E T, Lance, A, Fischer, K, Maresh, A, Edwards, M A, Mascelli

Publikováno v: Journal of thrombosis and thrombolysis. 9(1)

Ticlopidine and abciximab are two antiplatelet agents that are frequently administered during percutaneous coronary interventions. Although they have different mechanisms of action and pharmacological profiles, the two agents are often concomitantly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e93c8ab49a9b25e22df6bcd36e8d5ba4
https://pubmed.ncbi.nlm.nih.gov/10590186

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Human monoclonal antibody HA-1A binds to endotoxin via an epitope in the lipid A domain of lipopolysaccharide

Autor: W C, Bogard, S A, Siegel, A O, Leone, E, Damiano, D J, Shealy, T M, Ely, B, Frederick, M A, Mascelli, R C, Siegel, B, Machielse

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 150(10)

HA-1A, a human IgM mAb, has been shown to significantly reduce mortality in septic patients with Gram-negative bacteremia, especially those with septic shock, in a controlled clinical trial. To confirm the reported specificity of this antibody for th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dfdc561d3524004c9a18d38b977966fd
https://pubmed.ncbi.nlm.nih.gov/7683319

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Ig H and L chain contributions to autoimmune specificities

Autor: M Z, Radic, M A, Mascelli, J, Erikson, H, Shan, M, Weigert

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 146(1)

An Ig H chain expression vector has been constructed by using the V region of 3H9, an antibody that binds ssDNA, dsDNA, and cardiolipin. The H chain construct was transfected into six hybridoma cell lines expressing Ig L chains. All resulting H and L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5a6583369cebe282b458750c602e4fe8
https://pubmed.ncbi.nlm.nih.gov/1898596

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