Zobrazeno 1 - 10
of 283
pro vyhledávání: '"M. A. Kenney"'
Publikováno v:
Geoscience Communication, Vol 6, Pp 27-38 (2023)
Across the Midwest region of the United States, agriculturalists make decisions on a variety of timescales, ranging from daily to weekly, monthly, and seasonally. Ever-improving forecasts and decision support tools could assist the decision-making pr
Externí odkaz:
https://doaj.org/article/e2e4249277024764830af1fd9c0d96c2
Autor:
Kevin Schneider, Marilyn Chwa, Shari R. Atilano, Sonali Nashine, Nitin Udar, David S. Boyer, S. Michal Jazwinski, Michael V. Miceli, Anthony B. Nesburn, Baruch D. Kuppermann, M. Cristina Kenney
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 10, Pp 675-689 (2022)
Abstract Activation of the Simulator of Interferon Genes (STING) system by mitochondrial (mt) DNA can upregulate type 1 interferon genes and enhance immune responses to combat bacterial and viral infections. In cancers, the tumor‐derived DNA activa
Externí odkaz:
https://doaj.org/article/09bf357e9bfd42d796eda35f47c0bc9b
Autor:
Aneesh Neekhra, Julia Tran, Parsa R. Esfahani, Kevin Schneider, Khoa Pham, Ashish Sharma, Marilyn Chwa, Saurabh Luthra, Ana L. Gramajo, Saffar Mansoor, Baruch D. Kuppermann, M. Cristina Kenney
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 15, Pp 470-480 (2020)
Purpose: 7-ketocholesterol (7kCh), a natural byproduct of oxidation in lipoprotein deposits is implicated in the pathogenesis of diabetic retinopathy and age-related macular degeneration (AMD). This study was performed to investigate whether several
Externí odkaz:
https://doaj.org/article/295d056fd3cc4cc0855f0b3f4cee8e80
Autor:
Shari R. Atilano, Sina Abedi, Narcisa V. Ianopol, Mithalesh K. Singh, J Lucas Norman, Deepika Malik, Payam Falatoonzadeh, Marilyn Chwa, Anthony B. Nesburn, Baruch D. Kuppermann, M. Cristina Kenney
Publikováno v:
Cells, Vol 11, Iss 17, p 2655 (2022)
Mitochondrial (mt) DNA can be classified into haplogroups, which represent populations with different geographic origins. Individuals of maternal African backgrounds (L haplogroup) are more prone to develop specific diseases compared those with mater
Externí odkaz:
https://doaj.org/article/6a9ff33f61e44626ae55f0c5cdf9fcde
Autor:
Shari R Atilano, Nitin Udar, Timothy A Satalich, Viraat Udar, Marilyn Chwa, M Cristina Kenney
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0246114 (2021)
PurposeMitochondrial (mt) DNA damage is associated with age-related macular degeneration (AMD) and other human aging diseases. This study was designed to quantify and characterize mtDNA low-frequency heteroplasmy single nucleotide polymorphisms (SNPs
Externí odkaz:
https://doaj.org/article/35dabe7f52a0467a930d0acb2e3c19c2
Autor:
Jeffrey J. Yu, Daniel B. Azzam, Marilyn Chwa, Kevin Schneider, Jang-Hyeon Cho, Chinhui Hsiang, Henry Klassen, M. Cristina Kenney, Jing Yang
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Purpose. One of the leading causes of irreversible blindness worldwide, age-related macular degeneration (AMD) is a progressive disorder leading to retinal degeneration. While several treatment options exist for the exudative form of AMD, there are c
Externí odkaz:
https://doaj.org/article/92fac7ff71184a139c5d9bc4bcf8ba26
Autor:
Nasim Salimiaghdam, Lata Singh, Mithalesh K. Singh, Marilyn Chwa, Shari R. Atilano, Zahra Mohtashami, Anthony B. Nesburn, Baruch D. Kuppermann, Stephanie Y. Lu, M. Cristina Kenney
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 675 (2022)
We assessed the potential negative effects of bacteriostatic and bactericidal antibiotics on the AMD cybrid cell lines (K, U and J haplogroups). AMD cybrid cells were created and cultured in 96-well plates and treated with tetracycline (TETRA) and ci
Externí odkaz:
https://doaj.org/article/a23239b1136c4a09a66c438dc36b7bd3
Autor:
Lata Singh, Nasim Salimiaghdam, Kevin Schneider, Angele Nalbandian, Marilyn Chwa, Shari R Atilano, Andrea Bao, M Cristina Kenney
Publikováno v:
BMJ Open Ophthalmology, Vol 5, Iss 1 (2020)
Background We aim to determine the possible adverse effects of ciprofloxacin (CPFX) and tetracycline (TETRA), as examples of bactericidal and bacteriostatic agents, respectively, on cultured human retinal pigment epithelial cells (ARPE-19).Methods Ce
Externí odkaz:
https://doaj.org/article/b225632cc6f7451290919d020cd4be45
Autor:
Sina Abedi, Gregory Yung, Shari R. Atilano, Kunal Thaker, Steven Chang, Marilyn Chwa, Kevin Schneider, Nitin Udar, Daniela Bota, M. Cristina Kenney
Publikováno v:
PeerJ, Vol 8, p e9908 (2020)
Background Drug therapy yields different results depending on its recipient population. Cisplatin, a commonly used chemotherapeutic agent, causes different levels of resistance and side effects for different patients, but the mechanism(s) are present
Externí odkaz:
https://doaj.org/article/ef7b066f4c99462ba14fb3f9dd0f107a
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 7 (2020)
Background Mitochondrial transplantation has been recently explored for treatment of very ill cardiac patients. However, little is known about the intracellular consequences of mitochondrial transplantation. This study aims to assess the bioenergetic
Externí odkaz:
https://doaj.org/article/06e3641394ce4ef1b15b0e938c1935a8