Výsledky vyhledávání - "M. A. Jobling"

Cyclic AMP-independent effects of cholera toxin on B cell activation. II. Binding of ganglioside GM1 induces B cell activation

Autor: M L Francis, J Ryan, M G Jobling, R K Holmes, J Moss, J J Mond

Publikováno v: The Journal of Immunology. 148:1999-2005

Although the physiologic function of gangliosides is unknown, evidence suggests they play a role in the regulation of cell growth. The binding of ganglioside GM1 by recombinant B subunit of cholera toxin (rCT-B) inhibited mitogen-stimulated B cell pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::321d1b820d81b3a3f0e107f9c86ad776
https://doi.org/10.4049/jimmunol.148.7.1999

Zobrazit plný text záznamu

Structural biology of prions

Autor: R, Cappai, M F, Jobling, C J, Barrow, S, Collins

Publikováno v: Contributions to microbiology. 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc6af4308578ef4d206e6fc017cb9709
https://pubmed.ncbi.nlm.nih.gov/11923934

Zobrazit plný text záznamu

Haploid chromosomes in molecular ecology: lessons from the human Y

Autor: M E, Hurles, M A, Jobling

Publikováno v: Molecular ecology. 10(7)

We review the potential use of haploid chromosomes in molecular ecology, using recent work on the human Y chromosome as a paradigm. Chromosomal sex-determination systems, and hence constitutively haploid chromosomes, which escape from recombination o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c8ce6c06cad3f7a8f0ef1e9eff577f22
https://pubmed.ncbi.nlm.nih.gov/11472529

Zobrazit plný text záznamu

Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways

Autor: A R, White, X, Huang, M F, Jobling, C J, Barrow, K, Beyreuther, C L, Masters, A I, Bush, R, Cappai

Publikováno v: Journal of neurochemistry. 76(5)

Oxidative stress may have an important role in the progression of neurodegenerative disorders such as Alzheimer's disease (AD) and prion diseases. Oxidative damage could result from interactions between highly reactive transition metals such as coppe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e44d022358a0dc26c1f2d78c72143048
https://pubmed.ncbi.nlm.nih.gov/11238735

Zobrazit plný text záznamu

Clinal variation of YAP+ Y-chromosome frequencies in Western Iberia

Autor: L, Pereira, M J, Prata, M, Brión, M A, Jobling, A, Carracedo, A, Amorim

Publikováno v: Human biology. 72(6)

The potential of Y-chromosome biallelic marker haplotypes to infer population affiliations and structures was exploited to analyze four populations from the southwestern edge of Europe, namely north, central, and south Portugal and Galicia. Three mar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::851ee4e8d848b2fb990cb9307a0ac910
https://pubmed.ncbi.nlm.nih.gov/11236865

Zobrazit plný text záznamu

Characterization of hapR, a positive regulator of the Vibrio cholerae HA/protease gene hap, and its identification as a functional homologue of the Vibrio harveyi luxR gene

Autor: M G, Jobling, R K, Holmes

Publikováno v: Molecular microbiology. 26(5)

The Vibrio cholerae HA/protease gene (hap) promoter is inactive in Escherichia coli. We cloned and sequenced the 0.7kb hap promoter fragment from strain 3083-2 and showed that hap is located immediately 3' of ompW, encoding a minor outer membrane pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e5babb632c6014b725744ec9fec388d
https://pubmed.ncbi.nlm.nih.gov/9426139

Zobrazit plný text záznamu

Proteolytic activation of cholera toxin and Escherichia coli labile toxin by entry into host epithelial cells. Signal transduction by a protease-resistant toxin variant

Autor: W I, Lencer, C, Constable, S, Moe, P A, Rufo, A, Wolf, M G, Jobling, S P, Ruston, J L, Madara, R K, Holmes, T R, Hirst

Publikováno v: The Journal of biological chemistry. 272(24)

Cholera and Escherichia coli heat-labile toxins (CT and LT) require proteolysis of a peptide loop connecting two major domains of their enzymatic A subunits for maximal activity (termed "nicking"). To test whether host intestinal epithelial cells may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e1db96271abd0fed0fc4821fe83f532c
https://pubmed.ncbi.nlm.nih.gov/9182593

Zobrazit plný text záznamu

Digital DNA typing of human paternal lineages

Autor: N. Fretwell, A. J. Jeffreys, M. A. Jobling, N. Bouzekri, G. A. Dover

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba27cce78c5330e39aa7dc419e45354d
https://doi.org/10.1017/cbo9780511525643.003

Zobrazit plný text záznamu

Frequency of rare mitochondrial DNA mutations in patients with suspected Leber's hereditary optic neuropathy

Autor: Douglass M. Turnbull, Robert W. Taylor, Patrick F. Chinnery, M S Jobling

Publikováno v: Journal of Medical Genetics. 40:85e-85

Leber’s hereditary optic neuropathy (LHON (MIM 535000)) characteristically presents with subacute painless bilateral visual failure in young adults, with a predilection for males.1,2 In the largest multicentre study of white people with LHON,3 97%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf711aa4b81ed9e14981690a7ea0cf51
https://doi.org/10.1136/jmg.40.7.e85

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání