Inducing mismatch repair deficiency sensitizes immune-cold neuroblastoma to anti-CTLA4 and generates broad anti-tumor immune memory

Autor: Mikal El-Hajjar, Lara Gerhardt, Megan M Y Hong, Mithunah Krishnamoorthy, Rene Figueredo, Xiufen Zheng, James Koropatnick, Saman Maleki Vareki

Publikováno v: Molecular Therapy. 31:535-551

Immune checkpoint blockade can induce potent and durable responses in patients with highly immunogenic mismatch repair-deficient tumors; however, these drugs are ineffective against immune-cold neuroblastoma tumors. To establish a role for a T cell-b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6be47af0ce3e39a6867edc567c153a
https://doi.org/10.1016/j.ymthe.2022.08.025

Genetic background of sinus node dysfunction requiring permanent pacemaker implantation after atrial fibrillation catheter ablation

Autor: J W Park, M H Hong, D H Kim, H T Yu, T H Kim, J S Uhm, B Y Joung, M H Lee, C Hwang, H N Pak

Publikováno v: Europace. 25

Funding Acknowledgements Type of funding sources: None. Introduction Atrial fibrillation catheter ablation (AFCA) improves sinus node function and may defer a permanent pacemaker (PPM) implantation. We explored the clinical and genetic characteristic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba404bd1c846982e0ef5a335d1d7df6b
https://doi.org/10.1093/europace/euad122.599

STANDWISE CHANGE DETECTION FOR GROWING STOCK USING REPEAT-PASS ALOS PALSAR / PALSAR-2 DATA

Autor: M. –G. Hong, C. Kim

Publikováno v: The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XLI-B7, Pp 841-845 (2016)

This study demonstrates the possibility of detecting the changes of growing stocks in mountainous forest stands derived from ALOS PALSAR and PALSAR-2 images. The ALOS PALSAR were obtained over the Kwangneung Experiment Forest (KEF, Korea) during the

Externí odkaz: https://doaj.org/article/997a147afc454422a327bb9e8f5c35f8

Pharmacogenomics of GLP-1 receptor agonists : a genome-wide analysis of observational data and large randomised controlled trials

Autor: Adem Y Dawed, Andrea Mari, Andrew Brown, Timothy J McDonald, Lin Li, Shuaicheng Wang, Mun-Gwan Hong, Sapna Sharma, Neil R Robertson, Anubha Mahajan, Xuan Wang, Mark Walker, Stephen Gough, Leen M ‘t Hart, Kaixin Zhou, Ian Forgie, Hartmut Ruetten, Imre Pavo, Pallav Bhatnagar, Angus G Jones, Ewan R Pearson, L.M. 't Hart, M. Abdalla, J. Adam, J. Adamski, K. Adragni, K.H. Allin, M. Arumugam, N. Atabaki Pasdar, T. Baltauss, K.B. Banasik, P. Baum, J.D. Bell, M. Bergstrom, J.W. Beulens, S. Bianzano, R. Bizzotto, A. Bonneford, C.A.B. Brorsson, A.A. Brown, S.B. Brunak, L. Cabrelli, R. Caiazzo, M. Canouil, M. Dale, D. Davtian, A.Y. Dawed, F.M. De Masi, N. de Preville, K.F. Dekkers, E.T. Dermitzakis, H.A. Deshmukh, C. Dings, L. Donnelly, A. Dutta, B. Ehrhardt, P.J.M. Elders, C.E.T. Engel Thomas, L. Engelbrechtsen, R.G. Eriksen, R.E. Eriksen, Y. Fan, J. Fernandez, J. Ferrer, H. Fitipaldi, I.M. Forgie, A. Forman, P.W. Franks, F. Frau, A. Fritsche, P. Froguel, G. Frost, J. Gassenhuber, G.N. Giordano, T. Giorgino, S. Gough, U. Graefe-Mody, H. Grallert, R. Grempler, L. Groeneveld, L. Groop, V.G. Gudmundsdóttir, R.G. Gupta, M. Haid, T. Hansen, T.H. Hansen, A.T. Hattersley, R.S. Haussler, A.J. Heggie, A.M. Hennige, A.V. Hill, R.W. Holl, M.-G. Hong, M. Hudson, B. Jablonka, C. Jennison, J. Jiao, J.J. Johansen, A.G. Jones, A. Jonsson, T.K. Karaderi, J. Kaye, M. Klintenberg, R.W. Koivula, T. Kokkola, A.D.M. Koopman, A Kurbasic, T. Kuulasmaa, M. Laakso, T. Lehr, H. Loftus, R.L.A Lundbye Allesøe, A. Mahajan, A. Mari, G.M. Mazzoni, M.I. McCarthy, T.J. McDonald, D. McEvoy, N. McRobert, I. McVittie, M. Mourby, P. Musholt, P Mutie, R. Nice, C. Nicolay, A.M.N. Nielsen, B.N. Nilsson, C.N. Palmer, F. Pattou, I. Pavo, E.R. Pearson, O. Pedersen, H.K.P. Pedersen, M.H. Perry, H. Pomares-Millan, A. Ramisch, S.R. Rasmussen, V. Raverdi, M. Ridderstrale, N. Robertson, R.C. Roderick, M. Rodriquez, H. Ruetten, F. Rutters, W. Sackett, N. Scherer, J.M. Schwenk, N. Shah, S. Sharma, I. Sihinevich, N.B. Sondertoft, H. Staerfeldt, B. Steckel-Hamann, H. Teare, M.K. Thomas, E.L. Thomas, H.S. Thomsen, B. Thorand, C.E. Thorne, J. Tillner, A.T.L. Troen Lundgaard, M. Troll, K.D.T. Tsirigos, A. Tura, M. Uhlen, N. van Leeuwen, S. van Oort, H. Verkindt, H. Vestergaard, A. Viñuela, J.K Vogt, P.W.S Wad Sackett, D. Wake, M. Walker, A. Wesolowska-Andersen, B. Whitcher, M.W. White, H. Wu

Publikováno v: DIRECT consortium 2023, ' Pharmacogenomics of GLP-1 receptor agonists : a genome-wide analysis of observational data and large randomised controlled trials ', The Lancet Diabetes and Endocrinology, vol. 11, no. 1, pp. 33-41 . https://doi.org/10.1016/S2213-8587(22)00340-0
The Lancet Diabetes & Endocrinology, 11(1), 33-41. ELSEVIER SCIENCE INC
The Lancet Diabetes and Endocrinology, 11(1), 33-41. Elsevier BV

Background: In the treatment of type 2 diabetes, GLP-1 receptor agonists lower blood glucose concentrations, body weight, and have cardiovascular benefits. The efficacy and side effects of GLP-1 receptor agonists vary between people. Human pharmacoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090a81ca93ab346ddb1e6191899c14b3
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-496271

Nonlinear optics in germanium mid-infrared fiber material: Detuning oscillations in femtosecond mid-infrared spectroscopy

Autor: M. Ordu, J. Guo, G. Ng Pack, P. Shah, S. Ramachandran, M. K. Hong, L. D. Ziegler, S. N. Basu, S. Erramilli

Publikováno v: AIP Advances, Vol 7, Iss 9, Pp 095125-095125-8 (2017)

Germanium optical fibers hold great promise in extending semiconductor photonics into the fundamentally important mid-infrared region of the electromagnetic spectrum. The demonstration of nonlinear response in fabricated Ge fiber samples is a key ste

Externí odkaz: https://doaj.org/article/48e6ce6dc8d14b37b17f32ca2cb15d0c