Zobrazeno 1 - 10
of 37
pro vyhledávání: '"M. A. Hollinger"'
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 276:L311-L318
Pirfenidone (PD) is known for its antifibrotic effects in the bleomycin (BL) hamster model of lung fibrosis. We evaluated whether pretreatment of hamsters with PD could influence the effects of BL-induced overexpression of platelet-derived growth fac
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 18:334-342
We have reported that taurine (T) and niacin (N) inhibit the expression of procollagen type I and type III genes at the level of gene transcription in the bleomycin (BL) hamster model of lung fibrosis. In the present study, we have investigated the e
Publikováno v:
The Journal of biological chemistry. 275(18)
The recent identification of two new thrombin receptors, PAR3 and PAR4, led us to re-examine the basis for endothelial cell responses to thrombin. Human umbilical vein endothelial cells (HUVEC) are known to express PAR1 and the trypsin/tryptase recep
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(2)
Taurine (T) and niacin (N) have previously been found to block the accumulation of collagen in the bleomycin (BL) model of interstitial pulmonary fibrosis. The present study was designed to evaluate whether the mechanism for the antifibrotic effect o
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(1)
Therapeutic use of amiodarone (AD), an effective antiarrhythmic drug, is associated with serious pulmonary toxicity (e.g., fibrosis and phospholipidosis). In the present study, we tested if taurine and/or niacin, which prevent bleomycin-induced lung
Autor:
Lorenzo J. Abella, M. Bruce Hollinger
Publikováno v:
IEEE Transactions on Aerospace and Electronic Systems. :465-485
The announcement last summer of the establishment of the U. S. Navy Space Command, and its subsequent activation at Dahlgren, Va., in October 1983, may have come as a surprise to some. This, however, was the latest of a series of actions taken by the
Autor:
J. R. Davis, M. A. Hollinger
Publikováno v:
Reproduction. 19:585-589
The effect of nitrofurazone on the aerobic metabolism of uniformly labeled carbon-14 glucose in tissue slices of rat testes was investigated. .1% nitrofurazone was added to the diet of 60-day-old male rats for 30 days. Testicular slices were incubate
Publikováno v:
Toxicology. 2(3)
Intraperitoneal (i.p.) injections of toxic amounts of thiourea result in pulmonary edema and pleural effusions. Following i.p. injections of sublethal doses a predominance of pleural effusion over pulmonary edema is demonstrated. Pleural effusion res
Autor:
M A, Hollinger, F, Hwang
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 216(1)
The inhibitory effect of dibutyryl cyclic AMP (dbcAPM) on in vitro rat testis DNA synthesis appears to be relatively specific in nature. Of 7 organs studied, only testis and kidney in vitro DNA synthesis was significantly affected. In addition, anoth
Autor:
M A, Hollinger, M, Chvapil
Publikováno v:
Research communications in chemical pathology and pharmacology. 16(1)
Acute administration of Paraquat (25 mg/kg, I.P.) was found to significantly increase prolyl hydroxylase in rat lung 7 days following treatment. There was no change in total collagen at this time point. At 21 days following drug treatment, total coll