Zobrazeno 1 - 10
of 1 079
pro vyhledávání: '"M. A. Gordon"'
Autor:
Benjamin J. Strober, Karl Tayeb, Joshua Popp, Guanghao Qi, M. Grace Gordon, Richard Perez, Chun Jimmie Ye, Alexis Battle
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract Genetic regulation of gene expression is a complex process, with genetic effects known to vary across cellular contexts such as cell types and environmental conditions. We developed SURGE, a method for unsupervised discovery of context-speci
Externí odkaz:
https://doaj.org/article/913a45bed23149fdbebfd53e9e332fab
Autor:
Roy Oelen, Dylan H. de Vries, Harm Brugge, M. Grace Gordon, Martijn Vochteloo, single-cell eQTLGen consortium, BIOS Consortium, Chun J. Ye, Harm-Jan Westra, Lude Franke, Monique G. P. van der Wijst
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Not just differential gene expression but also differential gene regulation in immune cells account for individual differences in the immune response. Authors show here by single-cell RNA-sequencing of peripheral blood mononuclear cells from a large
Externí odkaz:
https://doaj.org/article/a0900e4955844d238d355bfc06a2a975
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Psychosis in Alzheimer’s disease (AD) represents a distinct disease subtype with a more rapid progression of illness evidenced by an increased velocity of cognitive decline and a hastened mortality. Previous biomarker and post-mortem studi
Externí odkaz:
https://doaj.org/article/1b2012ad11ba43f19ac0b9d81d2cbe5f
Publikováno v:
Journal of Political Economy; Sep2024, Vol. 132 Issue 9, p3025-3076, 52p
Publikováno v:
International Journal of Infectious Diseases, Vol 110, Iss , Pp 341-352 (2021)
ABSTRACT: Background: The case count for coronavirus disease 2019 (COVID-19) is the predominant measure used to track epidemiological dynamics and inform policy decision-making. Case counts, however, are influenced by testing rates and strategies, wh
Externí odkaz:
https://doaj.org/article/7a6ca076413549afaeaad098f6dc13e8
Autor:
Shaona Acharjee, Paul M. K. Gordon, Benjamin H. Lee, Justin Read, Matthew L. Workentine, Keith A. Sharkey, Quentin J. Pittman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Microglia play an important role in the pathogenesis of multiple sclerosis and the mouse model of MS, experimental autoimmune encephalomyelitis (EAE). To more fully understand the role of microglia in EAE we characterized microglial transcri
Externí odkaz:
https://doaj.org/article/3d560b4984894d3a9e47097a0d613700
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009350 (2021)
Nanopore sequencing device analysis systems simultaneously generate multiple picoamperage current signals representing the passage of DNA or RNA nucleotides ratcheted through a biomolecule nanopore array by motor proteins. Squiggles are a noisy and t
Externí odkaz:
https://doaj.org/article/c93dfe1860d04d21b65897a745226eb3
Autor:
Jackie K. Zorz, Christine Sharp, Manuel Kleiner, Paul M. K. Gordon, Richard T. Pon, Xiaoli Dong, Marc Strous
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Alkaline lakes have some of the highest productivity rates in freshwater ecosystems. Here the authors report amplicon, metagenome, and proteome sequencing from microbial mat communities of four alkaline lakes in Canada, and compare these lakes to cen
Externí odkaz:
https://doaj.org/article/6c981e2cb8e8427c83bee701fe9a395e
Autor:
Mahmoud M. Mostafa, Christopher F. Rider, Suharsh Shah, Suzanne L. Traves, Paul M. K. Gordon, Anna Miller-Larsson, Richard Leigh, Robert Newton
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-21 (2019)
Abstract Background Glucocorticoids act on the glucocorticoid receptor (GR; NR3C1) to resolve inflammation and, as inhaled corticosteroids (ICS), are the cornerstone of treatment for asthma. However, reduced efficacy in severe disease or exacerbation
Externí odkaz:
https://doaj.org/article/1a9e7ea088084058a8db7840158c236d
Autor:
Mollie M. Van Gordon
Publikováno v:
International Journal of Infectious Diseases, Vol 112, Iss , Pp 235-236 (2021)
Externí odkaz:
https://doaj.org/article/ee5ff000f37743b1b736ef8181bd9ff7