Zobrazeno 1 - 10
of 125
pro vyhledávání: '"M. A. Deacon"'
Autor:
Matias Mugnaini, Diana Polania, Yannina Diaz, Marcelo Ezquer, Fernando Ezquer, Robert M. J. Deacon, Patricia Cogram, Emilio Kropff
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The Octodon degus is a South American rodent that is receiving increased attention as a potential model of aging and sporadic late-onset Alzheimer’s disease (AD). Impairments in spatial memory tasks in Octodon degus have been reported in r
Externí odkaz:
https://doaj.org/article/495e7d45e4dc417c892dacd7bb1a3553
Autor:
Samantha T. Reyes, Robert M. J. Deacon, Scarlett G. Guo, Francisco J. Altimiras, Jessa B. Castillo, Berend van der Wildt, Aimara P. Morales, Jun Hyung Park, Daniel Klamer, Jarrett Rosenberg, Lindsay M. Oberman, Nell Rebowe, Jeffrey Sprouse, Christopher U. Missling, Christopher R. McCurdy, Patricia Cogram, Walter E. Kaufmann, Frederick T. Chin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Fragile X syndrome (FXS), a disorder of synaptic development and function, is the most prevalent genetic form of intellectual disability and autism spectrum disorder. FXS mouse models display clinically-relevant phenotypes, such as increased
Externí odkaz:
https://doaj.org/article/3fe726770d9a49e4a8f47d5b5a43daca
Autor:
Patricia Cogram, Daniel L. Alkon, David Crockford, Robert M. J. Deacon, Michael J. Hurley, Francisco Altimiras, Miao-Kun Sun, Michael Tranfaglia
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Fragile X syndrome (FXS), an X-chromosome linked intellectual disability, is the leading monogenetic cause of autism spectrum disorder (ASD), a neurodevelopmental condition that currently has no specific drug treatment. Building upon the dem
Externí odkaz:
https://doaj.org/article/00287d6d1cc84304aef691c3d36f1b59
Autor:
Patricia Cogram, Robert M. J. Deacon, Jennifer L. Warner-Schmidt, Melanie J. von Schimmelmann, Brett S. Abrahams, Matthew J. During
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Fragile X syndrome (FXS) is the most common inherited form of intellectual disability and autism. FXS is also accompanied by attention problems, hyperactivity, anxiety, aggression, poor sleep, repetitive behaviors, and self-injury. Recent work suppor
Externí odkaz:
https://doaj.org/article/5557ad91553a46b1a65dbc4a6e653b6a
Autor:
Passainte S Hassaan, Abeer E Dief, Teshreen M Zeitoun, Azza M Baraka, Robert M J Deacon, Amany Elshorbagy
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220720 (2019)
Although monosodium glutamate (MSG)-induced neurotoxicity has been recognized for decades, the potential similarities of the MSG model to Alzheimer's disease (AD)-type neuropathology have only recently been investigated. MSG-treated mice were examine
Externí odkaz:
https://doaj.org/article/857b4664e8214120868a307669096703
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Externí odkaz:
https://doaj.org/article/81cec7eeffcb4edabd4ec4264833e7af
Autor:
Patricia Cogram, Robert M. J. Deacon, Daniel Klamer, Nell Rebowe, Jeffrey Sprouse, Samantha T. Reyes, Christopher U. Missling, Walter E. Kaufmann
Publikováno v:
American journal of medical genetics. Part AREFERENCES. 188(8)
Autor:
Berend van der Wildt, Daniel Klamer, Samantha T. Reyes, Jeffrey Sprouse, Robert M. J. Deacon, Nell Rebowe, Walter E. Kaufmann, Aimara P. Morales, Lindsay M. Oberman, Jarrett Rosenberg, Frederick T. Chin, Jun Hyung Park, Scarlett G. Guo, Francisco Altimiras, Christopher U. Missling, Jessa B. Castillo, Patricia Cogram, Christopher R. McCurdy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Fragile X syndrome (FXS), a disorder of synaptic development and function, is the most prevalent genetic form of intellectual disability and autism spectrum disorder. FXS mouse models display clinically-relevant phenotypes, such as increased anxiety
Reversal of behavioural phenotype by the cannabinoid-like compound VSN16R in fragile X syndrome mice
Autor:
David Baker, A. W. Edith Chan, Patricia Cogram, Robert M. J. Deacon, Michael J. Hurley, David L. Selwood
Publikováno v:
Brain
Fragile X syndrome is the most common inherited intellectual disability and mono-genetic cause of autism spectrum disorder. It is a neurodevelopmental condition occurring due to a CGG trinucleotide expansion in the FMR1 gene. Polymorphisms and varian
Autor:
Emilio Kropff, Claudio Angione, Peter W. Vanderklish, Patricia Cogram, Robert M. J. Deacon, Guido Sampieri, Matías Mugnaini
Publikováno v:
Alzheimer's & Dementia. 16
Fil: Mugnaini, Matias. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires. Fundacion Instituto Leloir. Instituto de Investigac