Výsledky vyhledávání - "M. A. Curran"

Akademický článek

The Iso2k database: a global compilation of paleo-δ18O and δ2H records to aid understanding of Common Era climate

Publikováno v: Earth System Science Data, Vol 12, Pp 2261-2288 (2020)

Reconstructions of global hydroclimate during the Common Era (CE; the past ∼2000 years) are important for providing context for current and future global environmental change. Stable isotope ratios in water are quantitative indicators of hydroclima

Externí odkaz: https://doaj.org/article/e4af7b037e9b44f9b2aab9a01674f159

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Akademický článek

Reorganization of Atlantic Waters at sub-polar latitudes linked to deep-water overflow in both glacial and interglacial climate states

Autor: D. E. Holmes, T. L. Babila, U. Ninnemann, G. Bromley, S. Tyrrell, G. A. Paterson, M. J. Curran, A. Morley

Publikováno v: Climate of the Past, Vol 18, Pp 989-1009 (2022)

While a large cryosphere may be a necessary boundary condition for millennial-scale events to persist, a growing body of evidence from previous interglacial periods suggests that high-magnitude climate events are possible during low-cryosphere climat

Externí odkaz: https://doaj.org/article/f0c1f9b915ea4cf6be326d88bd6ea405

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Akademický článek

Multiple Disruptions of Glial-Neuronal Networks in Epileptogenesis That Follows Prolonged Febrile Seizures

Autor: Gary P. Brennan, Megan M. Garcia-Curran, Katelin P. Patterson, Renhao Luo, Tallie Z. Baram

Publikováno v: Frontiers in Neurology, Vol 12 (2021)

Background and Rationale: Bi-directional neuronal-glial communication is a critical mediator of normal brain function and is disrupted in the epileptic brain. The potential role of aberrant microglia and astrocyte function during epileptogenesis is i

Externí odkaz: https://doaj.org/article/f4fa7057264b4718a44a40eeeb6815e5

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Akademický článek

Unexpected Transcriptional Programs Contribute to Hippocampal Memory Deficits and Neuronal Stunting after Early-Life Adversity

Autor: Jessica L. Bolton, Anton Schulmann, Megan M. Garcia-Curran, Limor Regev, Yuncai Chen, Noriko Kamei, Manlin Shao, Akanksha Singh-Taylor, Shan Jiang, Yoav Noam, Jenny Molet, Ali Mortazavi, Tallie Z. Baram

Publikováno v: Cell Reports, Vol 33, Iss 11, Pp 108511- (2020)

Summary: Early-life adversity (ELA) is associated with lifelong memory deficits, yet the responsible mechanisms remain unclear. We impose ELA by rearing rat pups in simulated poverty, assess hippocampal memory, and probe changes in gene expression, t

Externí odkaz: https://doaj.org/article/4bf6ad0ca44047a889a6263685153df9

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Akademický článek

A hypothesis for an alternative treatment for tobacco addiction: phenelzine, a monoamine oxidase inhibitor

Autor: Claude A. Curran, Roger A. Boshes, Daniel Y. Lee, Patrizia M. Coratti Curran, Beth Hott

Publikováno v: Tobacco Induced Diseases, Vol 16, Iss 1 (2018)

Background Current smoking cessation methods are primarily based on the theory that nicotine is the principal addicting compound overlooking the contribution of the monoamine oxidase inhibitors present in tobacco. Our study tests the hypothesis that

Externí odkaz: https://doaj.org/article/c77e2d1e7b6945f3b48e0ecfbde2583f

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In-situ fluorescence spectroscopy is a more rapid and resilient indicator of faecal contamination risk in drinking water than faecal indicator organisms

Autor: James P.R. Sorensen, Tim Goodall, Robert Lyness, Luiza C. Campos, Jacintha Nayebare, Alan MacDonald, Catherine M. Rushworth Curran, Michael Owor, Richard G. Taylor, Daniel S. Read, Andrew F. Carr, Lena Ciric, Robinah Kulabako

Publikováno v: Water research. 206

Faecal indicator organisms (FIOs) are limited in their ability to protect public health from the microbial contamination of drinking water because of their transience and time required to deliver a result. We evaluated alternative rapid, and potentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015ad2840b1b6114790ed26244a11031
https://pubmed.ncbi.nlm.nih.gov/34655933

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Augmented seizure susceptibility and hippocampal epileptogenesis in a translational mouse model of febrile status epilepticus

Autor: Tallie Z. Baram, Megan M. Garcia-Curran, Gissell A Sanchez, Jennifer Daglian, Alicia M. Hall, Renhao Luo, Kevin D Chen

Publikováno v: Epilepsia, vol 62, iss 3
Epilepsia

ObjectiveProlonged fever-induced seizures (febrile status epilepticus [FSE]) during early childhood increase the risk for later epilepsy, but the underlying mechanisms are incompletely understood. Experimental FSE (eFSE) in rats successfully models h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb25cad677935da7d746346628b44d9
https://escholarship.org/uc/item/5fh370dp

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Unexpected Transcriptional Programs Contribute to Hippocampal Memory Deficits and Neuronal Stunting after Early-Life Adversity

Autor: Akanksha Singh-Taylor, Yoav Noam, Limor Regev, Yuncai Chen, Anton Schulmann, Shan Jiang, Noriko Kamei, Ali Mortazavi, Tallie Z. Baram, Jenny Molet, Jessica L. Bolton, Manlin Shao, Megan M. Garcia-Curran

Publikováno v: Cell Reports, Vol 33, Iss 11, Pp 108511-(2020)
Cell reports, vol 33, iss 11
Cell reports

SUMMARY Early-life adversity (ELA) is associated with lifelong memory deficits, yet the responsible mechanisms remain unclear. We impose ELA by rearing rat pups in simulated poverty, assess hippocampal memory, and probe changes in gene expression, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a1659372482d9002d9303f0558f491
http://www.sciencedirect.com/science/article/pii/S221112472031500X

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