Zobrazeno 1 - 10
of 108
pro vyhledávání: '"M. A. Bychkov"'
Autor:
O. V. Shlepova, M. A. Shulepko, V. O. Shipunova, M. L. Bychkov, I. D. Kukushkin, I. A. Chulina, V. N. Azev, E. I. Shramova, V. A. Kazakov, A. M. Ismailova, Y. A. Palikova, V. A. Palikov, E. A. Kalabina, E. A. Shaykhutdinova, G. A. Slashcheva, E. A. Tukhovskaya, I. A. Dyachenko, A. N. Murashev, S. M. Deyev, M. P. Kirpichnikov, Z. O. Shenkarev, E. N. Lyukmanova
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
α7-Type nicotinic acetylcholine receptor (α7-nAChR) promotes the growth and metastasis of solid tumors. Secreted Ly6/uPAR-Related Protein 1 (SLURP-1) is a specific negative modulator of α7-nAChR produced by epithelial cells. Here, we investigated
Externí odkaz:
https://doaj.org/article/68ca419785d04cd79f6b4a41671b974e
Autor:
A. V. Isaev, R. S. Mukhin, A. V. Andreev, M. A. Bychkov, M. L. Chelnokov, V. I. Chepigin, H. M. Devaraja, O. Dorvaux, M. Forge, B. Gall, K. Hauschild, I. N. Izosimov, K. Kessaci, A. A. Kuznetsova, A. Lopez-Martens, O. N. Malyshev, A. G. Popeko, Yu. A. Popov, A. Rahmatinejad, B. Sailaubekov, T. M. Shneidman, E. A. Sokol, A. I. Svirikhin, D. A. Testov, M. S. Tezekbayeva, A. V. Yeremin, N. I. Zamyatin, K. Sh. Zhumadilov
Publikováno v:
The European Physical Journal A. 58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52063c14bfeb2196dae9d3440a93ebb2
https://doi.org/10.1140/epja/s10050-022-00761-3
https://doi.org/10.1140/epja/s10050-022-00761-3
Autor:
D. R. Naskhletashvili, V. A. Gorbunova, M. B. Bychkov, A. Kh. Bekyashev, V. B. Karakhan, V. A. Aleshin, D. M. Belov, E. A. Moskvina
Publikováno v:
Опухоли головы и шеи, Vol 0, Iss 3, Pp 56-58 (2015)
The main tasks of the study were to evaluate the efficiency of treatment and to estimate time to progression and survival rates in patients with recurrent glioblastomas receiving combination treatment with irinotecan and bevacizumab. Five (41.7 %) pa
Externí odkaz:
https://doaj.org/article/e78598738f204fd88bffc8976c116f71
Autor:
D. R. Naskhletashvili, V. A. Gorbunova, M. B. Bychkov, A. Kh. Bekyashev, V. B. Karakhan, V. A. Aleshin, D. M. Belov, E. A. Moskvina
Publikováno v:
Опухоли головы и шеи, Vol 0, Iss 3, Pp 63-65 (2015)
Since 2006, the N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, has been conducting an investigation of the efficiency of targeted therapy with gefitinib in patients with brain metastasis from non-small cell lung car
Externí odkaz:
https://doaj.org/article/efa611763642488881004821f2d740a4
Autor:
A. H. Bekyashev, V A Aleshin, V. B. Karakhan, D. R. Naskhletashvili, A. A. Pogosova, E. V. Prozorenko, K. E. Roshchina, M. B. Bychkov, D. M. Belov, E. A. Moskvina, Vera Gorbunova, T. G. Gasparyan, A. A. Mitrofanov
Publikováno v:
Russian Journal of Oncology. 25:146-153
Metastatic damage to the brain is a frequent manifestation in tumors of various localizations, including breast cancer. Until recently, systemic therapy of metastatic brain damage was of limited use; however, with the advent of targeted drugs that ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a5c76164bbb7dd720f56d95b5d99c10
https://doi.org/10.17816/1028-9984-2020-25-4-146-153
https://doi.org/10.17816/1028-9984-2020-25-4-146-153
Autor:
M. B Bychkov, A. E. Kuzminov
Publikováno v:
Russian Journal of Oncology. 25:127-135
The article present a review and experience from a a single institution on the morphology, diagnostics, and treatment (chemotherapy, radiation, targeted therapy, and immunotherapy)) of small cell lung cancer (SCLC). The characteristic molecular, gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a89faf429e822cbdacb2ef787455e6c6
https://doi.org/10.17816/1028-9984-2020-25-4-127-135
https://doi.org/10.17816/1028-9984-2020-25-4-127-135
Publikováno v:
Doklady Biochemistry and Biophysics. 493:211-214
The alpha7 nicotinic acetylcholine receptor (α7-nAChR) is considered a promising pharmacological target for the carcinoma therapy. We have previously shown that the recombinant analogue of the human protein SLURP-1 (rSLURP-1) effectively inhibits th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06c0343da6418784f2d25ecd88342c3
https://doi.org/10.1134/s1607672920040134
https://doi.org/10.1134/s1607672920040134
Autor:
Anfisa Popova, Olga V. Shlepova, Alexander Andreev-Andrievskiy, Dmitry A. Dolgikh, D.S. Kulbatskii, Nathalia A. Vasilyeva, Zakhar O. Shenkarev, Sergey A. Kozlov, Pavel M. Balaban, Sergey G. Koshelev, Eugene V. Loktyushov, M L Bychkov, Ekaterina N. Lyukmanova, Mikhail A. Shulepko, M. Thomsen, Evgeniya A. Lagereva, Mikhail P. Kirpichnikov
Publikováno v:
Journal of Neurochemistry. 155:45-61
Lynx1 is a GPI-tethered protein colocalized with nicotinic acetylcholine receptors (nAChRs) in the brain areas important for learning and memory. Previously, we demonstrated that at low micromolar concentrations the water-soluble Lynx1 variant lackin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d8c2264ef841259e79c69140db7a80
https://doi.org/10.1111/jnc.15018
https://doi.org/10.1111/jnc.15018
Autor:
Mikhail P. Kirpichnikov, M L Bychkov, Olga V. Shlepova, Mikhail A. Shulepko, Ekaterina N. Lyukmanova
Publikováno v:
Доклады Академии наук. 489:517-520
The present study showed that the recombinant analogue of SLURP‑1 effectively inhibits the growth of a 3D model of tumors - multicellular spheroids from human epidermoid carcinoma A431 cells and human lung adenocarcinoma A549 cells. The combined ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2c50274ea203a9b2f83421a8ab4b168
https://doi.org/10.31857/s0869-56524895517-520
https://doi.org/10.31857/s0869-56524895517-520
Autor:
Alexey Semyanov, D.A. Aronov, Anna Fedotova, Ekaterina N. Lyukmanova, M L Bychkov, Alexei Verkhratsky, Alisa Tiaglik, Natalia Lazareva, Nadezda A. Brazhe, Alexey R. Brazhe, Li Li, Kseniia Morozova, Andrey Popov
SummaryA high-fat diet (HFD) is generally considered to negatively influence the body, the brain, and cognitive abilities. On the other hand, fat and fatty acids are essential for nourishing and constructing brain tissue. Astrocytes are central for l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e71b0d3bcd3589d65ec9836de358b31
https://doi.org/10.1101/2021.11.03.467141
https://doi.org/10.1101/2021.11.03.467141
