Zobrazeno 1 - 10
of 110
pro vyhledávání: '"M. A. Beaven"'
Autor:
M. A. Beaven, Y. S. Cho-Chung, Jacques Emile Dumont, T. T. Puck, L. S. Weistein, Jérôme Bertherat, S. M. Jan de Beur, Charis Eng, G. Tortora, W. R. Miller, K. V. Chin, Constantine A. Stratakis, E. Severin, G. M. Kammer, P. S. Amieux
Publikováno v:
Hormone and Metabolic Research. 34:169-175
This report summarizes several aspects of protein kinase A (PKA) signaling and its involvement in health and disease. It follows the discovery that PRKAR1A, the gene that codes for the relatively abundant regulatory subunit type 1A of protein kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a85a0bbc7032c973651be0440d8b2c3d
https://doi.org/10.1055/s-2002-26710
https://doi.org/10.1055/s-2002-26710
Publikováno v:
The Journal of Immunology. 157:4087-4093
We found that production and release of two functionally antagonistic cytokines, TGF-beta and TNF-alpha, were regulated differently in the mast cell, T cell, and macrophage cell lines RBL-2H3, MLA-144, and U-937, respectively. TGF-beta was produced a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99fe3fd864eb2343769c88a9cc53cb7d
https://doi.org/10.4049/jimmunol.157.9.4087
https://doi.org/10.4049/jimmunol.157.9.4087
Publikováno v:
The Journal of Immunology. 157:1625-1629
Ag stimulation of mast cells via the IgE receptor (Fc epsilon RI) elicits production and release of numerous cytokines. This activation of Fc epsilon RI initiates various tyrosine kinase-dependent signaling cascades, which ultimately result in the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::157fedd1fa5c1c816a62c23875bff79b
https://doi.org/10.4049/jimmunol.157.4.1625
https://doi.org/10.4049/jimmunol.157.4.1625
Publikováno v:
The Journal of Immunology. 154:5391-5402
The role of mitogen-activated protein (MAP) kinase in the release of arachidonic acid was examined in a mutated mast cell (RBL-2H3(m1)) line that expressed both native Fc epsilon R1 and the G protein-coupled muscarinic m1 receptor. Stimulation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5589fac4a3ad04b1bc4c7889553f9759
https://doi.org/10.4049/jimmunol.154.10.5391
https://doi.org/10.4049/jimmunol.154.10.5391
Publikováno v:
The Journal of Immunology. 153:2609-2617
Stimulated mast cells and cognate cultured cell lines produce and secrete a variety of cytokines including TNF. Because the mechanism by which cytokines are delivered to the external milieu is unknown, the release of TNF was studied in a rat mast cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e367eb8fbd12463c09791d4595b54f4
https://doi.org/10.4049/jimmunol.153.6.2609
https://doi.org/10.4049/jimmunol.153.6.2609
Publikováno v:
The Journal of Immunology. 151:5586-5595
Because of unresolved questions about the mechanism of Ag-stimulated Ca2+ influx, Ca2+ mobilization in response to carbachol and Ag was compared in transfected rat basophilic RBL-2H3(ml) cells that expressed both Fc epsilon and ml muscarinic receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaeecfcb4e0624a43deadd5946142d51
https://doi.org/10.4049/jimmunol.151.10.5586
https://doi.org/10.4049/jimmunol.151.10.5586
Publikováno v:
Journal of Biological Chemistry. 268:16887-16890
Mast cells release the mediators of the immediate hypersensitivity reaction. Adenosine is known to modulate this process, but the receptor responsible for this is not the classical A1 or A2 adenosine receptors. This study was undertaken to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a7e191f53f43727672d184c07684027
https://doi.org/10.1016/s0021-9258(19)85277-8
https://doi.org/10.1016/s0021-9258(19)85277-8
Publikováno v:
The Journal of Immunology. 149:1031-1037
Various inhibitors of phospholipases and serine/threonine kinases were used to determine whether activation of these enzymes was necessary for Ag-induced exocytosis in rat basophilic RBL-2H3 cells. Several inhibitors, however, inhibited events other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e28e5003daf816e9ca210792daf33b3a
https://doi.org/10.4049/jimmunol.149.3.1031
https://doi.org/10.4049/jimmunol.149.3.1031
Publikováno v:
The Journal of Immunology. 144:3449-3457
Prolonged exposure of rat basophilic leukemia (RBL-2H3) cells, a cultured analog of rat mast cells, to 0.1 microM dexamethasone resulted in global suppression of various stimulatory events in response to Ag and a global enhancement of the same stimul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf296f8c486ea4743f8566d635743ef1
https://doi.org/10.4049/jimmunol.144.9.3449
https://doi.org/10.4049/jimmunol.144.9.3449
Publikováno v:
The Journal of Immunology. 144:244-250
As reported by other workers, the treatment of rat basophilic leukemia RBL-2H3 cells with dexamethasone resulted in a marked decrease in responsiveness to Ag-stimulation. All responses measured, which included hydrolysis of inositol phospholipids, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5171634fca3a5e32ae107c845948723
https://doi.org/10.4049/jimmunol.144.1.244
https://doi.org/10.4049/jimmunol.144.1.244