Zobrazeno 1 - 10
of 253
pro vyhledávání: '"M. A. Aman"'
Autor:
Tania Wong Fok Lung, Liana C. Chan, Alice Prince, Michael R. Yeaman, Nathan K. Archer, M. Javad Aman, Richard A. Proctor
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Despite meritorious attempts, a S. aureus vaccine that prevents infection or mitigates severity has not yet achieved efficacy endpoints in prospective, randomized clinical trials. This experience underscores the complexity of host-S. aureus interacti
Externí odkaz:
https://doaj.org/article/bc573c1aa8194125a8ccfdafc9362db9
Autor:
Shweta Kailasan, Ravi Kant, Madeleine Noonan-Shueh, Tulasikumari Kanipakala, Grant Liao, Sergey Shulenin, Daisy W. Leung, Richard A. Alm, Rajan P. Adhikari, Gaya K. Amarasinghe, Michael L. Gross, M. Javad Aman
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Staphylococcus aureus carries an exceptional repertoire of virulence factors that aid in immune evasion. Previous single-target approaches for S. aureus-specific vaccines and monoclonal antibodies (mAbs) have failed in clinical trials due to the mult
Externí odkaz:
https://doaj.org/article/536d0a35d34246f88a85754222c857ae
Autor:
Krista Meserve, Abraham J. Qavi, M. Javad Aman, Hong Vu, Larry Zeitlin, John M. Dye, Jeffrey W. Froude, Daisy W. Leung, Lan Yang, Frederick W. Holtsberg, Gaya K. Amarasinghe, Ryan C. Bailey
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101719- (2022)
Summary: This protocol describes the use of silicon photonic microring resonator sensors for detection of Ebola virus (EBOV) and Sudan virus (SUDV) soluble glycoprotein (sGP). This protocol encompasses biosensor functionalization of silicon microring
Externí odkaz:
https://doaj.org/article/e9bbcc7f59114f908957058b53e324a5
Autor:
Xiaobing Han, Roger Ortines, Ipsita Mukherjee, Tulasikumari Kanipakala, Thomas Kort, Shardulendra P. Sherchand, Grant Liao, Mark Mednikov, Agnes L. Chenine, M. Javad Aman, Cory L. Nykiforuk, Rajan P. Adhikari
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Staphylococcus aureus has been acquiring multiple drug resistance and has evolved into superbugs such as Methicillin/Vancomycin-resistant S. aureus (MRSA/VRSA) and, consequently, is a major cause of nosocomial and community infections associated with
Externí odkaz:
https://doaj.org/article/8ed38ad2e8f142c89e8bcb9df02022af
Autor:
Tom Z. Yuan, Pankaj Garg, Linya Wang, Jordan R. Willis, Eric Kwan, Ana G Lujan Hernandez, Emily Tuscano, Emily N. Sever, Erica Keane, Cinque Soto, Eric M. Mucker, Mallorie E. Fouch, Edgar Davidson, Benjamin J. Doranz, Shweta Kailasan, M. Javad Aman, Haoyang Li, Jay W. Hooper, Erica Ollmann Saphire, James E. Crowe, Qiang Liu, Fumiko Axelrod, Aaron K. Sato
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Coronavirus disease 2019 (COVID-19) is an evolving global public health crisis in need of therapeutic options. Passive immunization of monoclonal antibodies (mAbs) represents a promising therapeutic strategy capable of conferring immediate protection
Externí odkaz:
https://doaj.org/article/b6c1901170674ee7807acd867a09110b
Autor:
Jennifer M. Brannan, Shihua He, Katie A. Howell, Laura I. Prugar, Wenjun Zhu, Hong Vu, Sergey Shulenin, Shweta Kailasan, Henna Raina, Gary Wong, Md Niaz Rahim, Logan Banadyga, Kevin Tierney, Xuelian Zhao, Yuxing Li, Frederick W. Holtsberg, John M. Dye, Xiangguo Qiu, M. Javad Aman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Current experimental monoclonal antibodies (mAbs) for Ebola virus (EBOV) post-exposure immunotherapy are ineffective against Sudan (SUDV) or Marburg virus (MARV). Here, authors develop cocktails of mAbs that protect nonhuman primates against EBOV, SU
Externí odkaz:
https://doaj.org/article/b99aa7a0e5ce4018ab41eac4e31287f3
Autor:
Ujjwol Khatri, Neetu Dayal, Xueqing Hu, Elizabeth Larocque, Nimishetti Naganna, Tao Shen, Xuan Liu, Frederick W. Holtsberg, M. Javad Aman, Herman O. Sintim, Jie Wu
Publikováno v:
Molecular Cancer Therapeutics. :OF1-OF9
Selpercatinib (LOXO292) and pralsetinib (BLU667) are RET protein tyrosine kinase inhibitors (TKIs) recently approved for treating RET-altered cancers. However, RET mutations that confer selpercatinib/pralsetinib resistance have been identified, neces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d9dfbe341515a18d8597b0374b233d7
https://doi.org/10.1158/1535-7163.mct-22-0629
https://doi.org/10.1158/1535-7163.mct-22-0629
Autor:
Gergely Imre, Verena Krähling, Madeleine Eichler, Sandra Trautmann, Nerea Ferreirós, M. Javad Aman, Fatah Kashanchi, Krishnaraj Rajalingam, Stefan Pöhlmann, Stephan Becker, Dagmar Meyer zu Heringdorf, Josef Pfeilschifter
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102266- (2021)
Summary: Ebola virus (EBOV) is responsible for outbreaks with case fatality rates of up to 90% and for an epidemic in West Africa with more than ten thousand deaths. EBOV glycoprotein (EBOV-GP) is the only viral surface protein and is responsible for
Externí odkaz:
https://doaj.org/article/a4d3b8fd63584eefb7be8371826ef0f5
Autor:
Hatice Karauzum, Arundhathi Venkatasubramaniam, Rajan P. Adhikari, Tom Kort, Frederick W. Holtsberg, Ipsita Mukherjee, Mark Mednikov, Roger Ortines, Nhu T. Q. Nguyen, Thien M. N. Doan, Binh An Diep, Jean C. Lee, M. Javad Aman
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Staphylococcus aureus causes a wide range of diseases from skin infections to life threatening invasive diseases such as bacteremia, endocarditis, pneumonia, surgical site infections, and osteomyelitis. Skin infections such as furuncles, carbuncles,
Externí odkaz:
https://doaj.org/article/5acc92f49b3f477d92f2e62b58561d28
Autor:
Arundhathi Venkatasubramaniam, Grant Liao, Eunice Cho, Rajan P. Adhikari, Tom Kort, Frederick W. Holtsberg, Karen E. Elsass, Dean J. Kobs, Thomas L. Rudge, Keith D. Kauffman, Nickiana E. Lora, Daniel L. Barber, M. Javad Aman, Hatice Karauzum
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Staphylococcus aureus is a leading cause of significant morbidity and mortality and an enormous economic burden to public health worldwide. Infections caused by methicillin-resistant S. aureus (MRSA) pose a major threat as MRSA strains are becoming i
Externí odkaz:
https://doaj.org/article/c83a2f964899456781ac389d4bee43fb