Výsledky vyhledávání - "M. A. Ajmone-Cat"

Akademický článek

Maternal suboptimal selenium intake and low-level lead exposure affect offspring’s microglial immune profile and its reactivity to a subsequent inflammatory hit

Autor: R. De Simone, M. A. Ajmone-Cat, A. M. Tartaglione, G. Calamandrei, L. Minghetti

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Abstract Micronutrients such as selenium (Se) are essentials since prenatal life to support brain and cognitive development. Se deficiency, which affects up to 1 billion people worldwide, can interact with common adverse environmental challenges incl

Externí odkaz: https://doaj.org/article/1bba045a9cc147f9903ca7bb589283c9

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Akademický článek

N-acetylcysteine counteracts increased brain excitatory/inhibitory balance following maternal high-fat diet and restores emotional and cognitive profiles in adult mouse offspring

Autor: C. Musillo, M. Samà, B. Collacchi, M. A. Ajmone-Cat, R. De Simone, K. C. Creutzberg, M. A. Riva, A. Berry, F. Cirulli

Publikováno v: European Psychiatry, Vol 67, Pp S84-S84 (2024)

Introduction High-fat diet (HFD) consumption during pregnancy can shape fetal brain development, increasing susceptibility to mental disorders. Nevertheless, the mechanisms underlying these negative outcomes remain unclear. Objectives We hypothesiz

Externí odkaz: https://doaj.org/article/68bb5e9a7a6041089dfd67c5565c9989

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Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis

Autor: M A, Ajmone-Cat, A, Nicolini, L, Minghetti

Publikováno v: Journal of neurochemistry. 87(5)

During inflammatory or degenerative processes microglial cells are likely to be exposed to activating agents that persist in brain parenchyma for prolonged periods. As our knowledge on microglial activation is largely based on in vitro studies in whi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f4d3fc8928965e2607a13bbecc325d4c
https://pubmed.ncbi.nlm.nih.gov/14622099

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Effects of phosphatidylserine on p38 mitogen activated protein kinase, cyclic AMP responding element binding protein and nuclear factor-kappaB activation in resting and activated microglial cells

Autor: M A, Ajmone-Cat, R, De Simone, A, Nicolini, L, Minghetti

Publikováno v: Journal of neurochemistry. 84(2)

In the last few years, the interaction between phosphatidylserine (PS), a phospholipid that becomes permanently exposed on the external cell surface in the early phases of apoptosis, and its specific receptor (PtdSerR) has emerged as a crucial event

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b3a470d752eeaadb3e975cf231508cad
https://pubmed.ncbi.nlm.nih.gov/12559004

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Human immunodeficiency virus type-1 Tat protein induces nuclear factor (NF)-kappaB activation and oxidative stress in microglial cultures by independent mechanisms

Autor: A, Nicolini, M A, Ajmone-Cat, A, Bernardo, G, Levi, L, Minghetti

Publikováno v: Journal of neurochemistry. 79(3)

We have extended our previous findings and shown that human immunodeficiency virus Tat protein, in addition to nitric oxide (NO), stimulated rat microglial cultures to release pro-inflammatory cytokine interleukin-1beta and tumour necrosis factor-alp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::63a37117ebc640fe530afb909c3ca961
https://pubmed.ncbi.nlm.nih.gov/11701774

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Modulation of acetylcholinesterase and voltage-gated Na(+) channels in choline acetyltransferase- transfected neuroblastoma clones

Autor: Pietro Baldelli, Emilio Carbone, S. Biagioni, M. A. Ajmone-Cat, A. De Jaco, Gabriella Augusti-Tocco

Neurotransmitters appear early in the developing embryo and may play a role in the regulation of neuronal differentiation. To study potential effects of acetylcholine production in neuronal differentiation, we used the FB5 subclone of N18TG2 murine n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4b13929586d8e4b0f0fbfdedf87724
http://hdl.handle.net/11567/194149

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