Zobrazeno 1 - 10
of 424
pro vyhledávání: '"M. A. Quinn"'
Autor:
Bruna Lopes da Costa, Peter M. J. Quinn, Wen-Hsuan Wu, Siyuan Liu, Nicholas D. Nolan, Aykut Demirkol, Yi-Ting Tsai, Salvatore Marco Caruso, Thiago Cabral, Nan-Kai Wang, Stephen H. Tsang
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Background Retinitis pigmentosa (RP) is a genetically heterogeneous group of degenerative disorders causing progressive vision loss due to photoreceptor death. RP affects other retinal cells, including the retinal pigment epithelium (RPE). M
Externí odkaz:
https://doaj.org/article/494ffbf7b8f74db6b5ae6c2415e1394c
Autor:
M. ONeill, C. Briciu-Burghina, E. Jennings, P. Antunes, D. Ó hUallacháin, M. Kelly-Quinn, M. O’Sullivan, F. Regan
Publikováno v:
Irish Journal of Agricultural and Food Research, Vol 62, Iss 1, Pp 7-17 (2023)
Unrestricted cattle access can have negative impacts on aquatic systems, including increases in stream water turbidity and suspended sediment levels. Many agri-environmental policies require the exclusion of livestock from waterbodies; however, data
Externí odkaz:
https://doaj.org/article/93162f22da6e4398b8db85449f840607
Autor:
Yang Kong, Pei‐Kang Liu, Yao Li, Nicholas D Nolan, Peter M J Quinn, Chun‐Wei Hsu, Laura A Jenny, Jin Zhao, Xuan Cui, Ya‐Ju Chang, Katherine J Wert, Janet R Sparrow, Nan‐Kai Wang, Stephen H Tsang
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp 1-20 (2023)
Abstract Iron accumulation causes cell death and disrupts tissue functions, which necessitates chelation therapy to reduce iron overload. However, clinical utilization of deferoxamine (DFO), an iron chelator, has been documented to give rise to syste
Externí odkaz:
https://doaj.org/article/dad16b5228fa4f2aae01a11f4bb1e21e
Autor:
Phasit Charoenkwan, Saeed Ahmed, Chanin Nantasenamat, Julian M. W. Quinn, Mohammad Ali Moni, Pietro Lio’, Watshara Shoombuatong
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Amyloid proteins have the ability to form insoluble fibril aggregates that have important pathogenic effects in many tissues. Such amyloidoses are prominently associated with common diseases such as type 2 diabetes, Alzheimer's disease, and
Externí odkaz:
https://doaj.org/article/154eb7d694ef4e3a87cee1d6e4f67cf2
Autor:
Saeed Ahmad, Phasit Charoenkwan, Julian M. W. Quinn, Mohammad Ali Moni, Md Mehedi Hasan, Pietro Lio’, Watshara Shoombuatong
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Fast and accurate identification of phage virion proteins (PVPs) would greatly aid facilitation of antibacterial drug discovery and development. Although, several research efforts based on machine learning (ML) methods have been made for in
Externí odkaz:
https://doaj.org/article/1cdc5a7406e5428eaf870c37270958db
Autor:
Scott E. Youlten, John P. Kemp, John G. Logan, Elena J. Ghirardello, Claudio M. Sergio, Michael R. G. Dack, Siobhan E. Guilfoyle, Victoria D. Leitch, Natalie C. Butterfield, Davide Komla-Ebri, Ryan C. Chai, Alexander P. Corr, James T. Smith, Sindhu T. Mohanty, John A. Morris, Michelle M. McDonald, Julian M. W. Quinn, Amelia R. McGlade, Nenad Bartonicek, Matt Jansson, Konstantinos Hatzikotoulas, Melita D. Irving, Ana Beleza-Meireles, Fernando Rivadeneira, Emma Duncan, J. Brent Richards, David J. Adams, Christopher J. Lelliott, Robert Brink, Tri Giang Phan, John A. Eisman, David M. Evans, Eleftheria Zeggini, Paul A. Baldock, J. H. Duncan Bassett, Graham R. Williams, Peter I. Croucher
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Osteocytes are the master regulatory cells within the skeleton. Here, the authors map the transcriptome of osteocytes from diverse skeletal sites, ages and between sexes and identify an osteocyte transcriptome signature associated with rare skeletal
Externí odkaz:
https://doaj.org/article/60182d9a653b4b4d9d0b7b34378bcb3e
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Psychiatric symptoms are seen in some COVID-19 patients, as direct or indirect sequelae, but it is unclear whether SARS-CoV-2 infection interacts with underlying neuronal or psychiatric susceptibilities. Such interactions might arise from CO
Externí odkaz:
https://doaj.org/article/0900675443a44fd788c1487a45367f09
Autor:
Md. Rashed-Al-Mahfuz, Abedul Haque, Akm Azad, Salem A. Alyami, Julian M. W. Quinn, Mohammad Ali Moni
Publikováno v:
IEEE Journal of Translational Engineering in Health and Medicine, Vol 9, Pp 1-11 (2021)
Objective: Chronic kidney disease (CKD) is a major public health concern worldwide. High costs of late-stage diagnosis and insufficient testing facilities can contribute to high morbidity and mortality rates in CKD patients, particularly in less deve
Externí odkaz:
https://doaj.org/article/c538d35f9bc040ee84b733dc6d0e21c1
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-20 (2020)
Abstract Mutations in the PTEN-induced kinase 1 (PINK1) and Parkin RBR E3 ubiquitin-protein ligase (PARKIN) genes are associated with familial forms of Parkinson’s disease (PD). PINK1, a protein kinase, and PARKIN, an E3 ubiquitin ligase, control t
Externí odkaz:
https://doaj.org/article/70c888ef25234b0f89e96f6c466f8d09
Autor:
Mohammad Ali Moni, M. Babul Islam, Md Rezanur Rahman, Md Rashed-Al-Mahfuz, Md Abdul Awal, Sheikh Mohammed Shariful Islam, Md. Nurul Haque Mollah, Julian M. W. Quinn
Publikováno v:
IEEE Access, Vol 8, Pp 1486-1497 (2020)
Developing type 2 diabetes (T2D) can increase patient risk of developing other common diseases and exacerbate their severity, including diseases that affect bone and joints. Such comorbidity interactions are hard to study in detail by traditional end
Externí odkaz:
https://doaj.org/article/11d3701215cf410aa76972807d3e25ce