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Autor:
G. C. M. Bruschi, N. R. Morris, C. C. de Souza, M. A C Dani, Marcia Regina von Zeska Kress Fagundes, Gustavo H. Goldman, Maria Helena S. Goldman, Leroy-Fong Liu
Publikováno v:
Molecular Genetics and Genomics. 265:264-275
The anti-cancer drug camptothecin targets eukaryotic DNA topoisomerase I by trapping the covalent complex formed between the catalytically active enzyme and DNA. We are interested in identifying factors, other than topoisomerase I, that are involved