Zobrazeno 1 - 10
of 357
pro vyhledávání: '"M. Reichardt"'
Autor:
Ariful Haque Abir, Leonie Weckwerth, Artur Wilhelm, Jana Thomas, Clara M. Reichardt, Luis Munoz, Simon Völkl, Uwe Appelt, Markus Mroz, Raluca Niesner, Anja Hauser, Rebecca Sophie Fischer, Katharina Pracht, Hans-Martin Jäck, Georg Schett, Gerhard Krönke, Dirk Mielenz
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101981- (2024)
Objective: The metabolism of different cells within the same microenvironment can differ and dictate physiological or pathological adaptions. Current single-cell analysis methods of metabolism are not label-free. Methods: The study introduces a label
Externí odkaz:
https://doaj.org/article/5b381a534cf04e8f9f71a6a2532ba488
Autor:
Fridolin Grottker, Simon Gehre, Clara M. Reichardt, Azzaya Sengedorj, Tina Jost, Thorsten Rieckmann, Markus Hecht, Antoniu-Oreste Gostian, Benjamin Frey, Rainer Fietkau, Udo S. Gaipl, Michael Rückert
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 45, Iss , Pp 100944- (2023)
Purpose: Human papilloma virus (HPV) positive head and neck squamous cell carcinoma (HNSCC) tumors respond significantly better to anticancer treatments. It is assumed to be due to a better response to radiotherapy (RT), and presumably to an increase
Externí odkaz:
https://doaj.org/article/3ae950bb462247bab8645708ee22896d
Autor:
Simon Gehre, Felix Meyer, Azzaya Sengedorj, Fridolin Grottker, Clara M. Reichardt, Jannik Alomo, Kerstin Borgmann, Benjamin Frey, Rainer Fietkau, Michael Rückert, Udo S. Gaipl
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Only a subset of patients with triple-negative breast cancer (TNBC) benefits from a combination of radio- (RT) and immunotherapy. Therefore, we aimed to examine the impact of radioresistance and brain metastasizing potential on the immunological phen
Externí odkaz:
https://doaj.org/article/2c3daa9acc1c4ab1be80ebca2d3caa0b
Autor:
Gesa J. Albers, Agathe Amouret, Katrin Ciupka, Elena Montes-Cobos, Claus Feldmann, Holger M. Reichardt
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16843 (2023)
Glucocorticoids (GCs) are widely used to treat inflammatory disorders such as acute lung injury (ALI). Here, we explored inorganic–organic hybrid nanoparticles (IOH-NPs) as a new delivery vehicle for GCs in a mouse model of ALI. Betamethasone (BMZ)
Externí odkaz:
https://doaj.org/article/40c63199529545569dcd67d59fde7494
Autor:
Chiara Muzzi, Norika Watanabe, Eric Twomey, Garrit K. Meers, Holger M. Reichardt, Hanibal Bohnenberger, Sybille D. Reichardt
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1505-1518 (2021)
Background & Aims: Inflammatory bowel disease is commonly treated by administration of glucocorticoids. While the importance of intestinal epithelial cells for the pathogenesis of this disorder is widely accepted, their role as target cells for gluco
Externí odkaz:
https://doaj.org/article/fa90ccd78aaf40c0a2a08e384bdb4121
Autor:
Leonie Meyer-Heemsoth, Katja Mitschke, Jasmina Bier, Konstantin Schütz, Andreas Villunger, Tobias J. Legler, Martin S. Weber, Fred Lühder, Holger M. Reichardt
Publikováno v:
Cells, Vol 12, Iss 3, p 450 (2023)
Glucocorticoids (GCs) are used to treat inflammatory disorders such as multiple sclerosis (MS) by exerting prominent activities in T cells including apoptosis induction and suppression of cytokine production. However, little is known about their impa
Externí odkaz:
https://doaj.org/article/7aa68e66f5924d57a5e3dda753c2a6fd
Autor:
Malte Tiburcy, Alex Markov, Lena K. Kraemer, Peter Christalla, Margret Rave‐Fraenk, Henrike J. Fischer, Holger M. Reichardt, Wolfram‐Hubertus Zimmermann
Publikováno v:
FASEB BioAdvances, Vol 1, Iss 12, Pp 731-746 (2019)
Abstract Satellite cells reside in defined niches and are activated upon skeletal muscle injury to facilitate regeneration. Mechanistic studies of skeletal muscle regeneration are hampered by the inability to faithfully simulate satellite cell biolog
Externí odkaz:
https://doaj.org/article/7b9d3c00f09b42efb6f04603c7aa7345
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Induction of T cell apoptosis constitutes a major mechanism by which therapeutically administered glucocorticoids (GCs) suppress inflammation and associated clinical symptoms, for instance in multiple sclerosis (MS) patients suffering from an acute r
Externí odkaz:
https://doaj.org/article/61f64426410445719c02ef8c2395a8a4
Publikováno v:
Cells, Vol 11, Iss 5, p 885 (2022)
Testicular germ cell cancer (TGCC) is the most common type of cancer in young men. Seminomas account for around half of them and are characterized by a pronounced infiltration of immune cells. So far, the impact of the tumor microenvironment (TME) on
Externí odkaz:
https://doaj.org/article/8eec330a22c14ae9985f7caa0bbf42b5
Autor:
Sybille D. Reichardt, Agathe Amouret, Chiara Muzzi, Sabine Vettorazzi, Jan P. Tuckermann, Fred Lühder, Holger M. Reichardt
Publikováno v:
Cells, Vol 10, Iss 11, p 2921 (2021)
For more than 70 years, glucocorticoids (GCs) have been a powerful and affordable treatment option for inflammatory diseases. However, their benefits do not come without a cost, since GCs also cause side effects. Therefore, strong efforts are being m
Externí odkaz:
https://doaj.org/article/8259bbf6ae884f8d95dec4607745f541