Zobrazeno 1 - 10
of 1 327
pro vyhledávání: '"M. Pascal"'
Autor:
Nicholas C. K. Valerie, Kumar Sanjiv, Oliver Mortusewicz, Si Min Zhang, Seher Alam, Maria J. Pires, Hannah Stigsdotter, Azita Rasti, Marie-France Langelier, Daniel Rehling, Adam Throup, Oryn Purewal-Sidhu, Matthieu Desroses, Jacob Onireti, Prasad Wakchaure, Ingrid Almlöf, Johan Boström, Luka Bevc, Giorgia Benzi, Pål Stenmark, John M. Pascal, Thomas Helleday, Brent D. G. Page, Mikael Altun
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Cellular target engagement technologies enable quantification of intracellular drug binding; however, simultaneous assessment of drug-associated phenotypes has proven challenging. Here, we present cellular target engagement by accumulation o
Externí odkaz:
https://doaj.org/article/da8b368cca654c56b35ce8a1e37b2285
Autor:
Jennings, Dylan a, b, ⁎, Zahler, M. Pascal a, Wang, Di c, Ma, Qianli a, Deibert, Wendelin a, Kindelmann, Moritz a, b, d, Kübel, Christian c, e, Baumann, Stefan a, Guillon, Olivier a, f, Mayer, Joachim b, d, Rheinheimer, Wolfgang a, g, h
Publikováno v:
In Acta Materialia 1 July 2024 273
Autor:
A. Lemonsu, J.M. Alessandrini, J. Capo, M. Claeys, E. Cordeau, C. de Munck, S. Dahech, J.C. Dupont, F. Dugay, V. Dupuis, G. Forceville, S. Garrigou, O. Garrouste, M. Goret, S. Goria, M. Haeffelin, S. Host, C. Joly, P. Keravec, S. Kotthaus, N. Laruelle, M. Madelin, V. Masson, C. Mauclair, T. Nagel, M. Pascal, J.F. Ribaud, G. Roberts, A. Rosso, A. Roy, M. Sabre, O. Sanchez, M. Stempfelet, W. Wei, R. Wilson, J. Wurtz
Publikováno v:
Climate Services, Vol 34, Iss , Pp 100472- (2024)
Externí odkaz:
https://doaj.org/article/ecdeffc8d69545148d0e4c69ebc1bc53
Akademický článek
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Autor:
Zahler, M. Pascal a, Jennings, Dylan a, b, Kindelmann, Moritz a, b, c, Guillon, Olivier a, d, e, Rheinheimer, Wolfgang a, d, ⁎
Publikováno v:
In Journal of the European Ceramic Society December 2023 43(15):6925-6933
Publikováno v:
Viruses, Vol 16, Iss 7, p 1009 (2024)
Enterovirus genomic replication initiates at a predicted RNA cloverleaf (5′CL) at the 5′ end of the RNA genome. The 5′CL contains one stem (SA) and three stem-loops (SLB, SLC, SLD). Here, we present an analysis of 5′CL conservation and diverg
Externí odkaz:
https://doaj.org/article/a1abac4efb97403c96628acbf0df7a93
Autor:
Zahler, M. Pascal a, Kraschewski, Simon M. b, c, Störmer, Heike b, Gerthsen, Dagmar b, Bäurer, Michael d, e, Rheinheimer, Wolfgang a, d, ⁎
Publikováno v:
In Journal of the European Ceramic Society April 2023 43(4):1613-1624
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
HPF1 controls the ADP-ribosylation activity of PARP1/2 in response to DNA breaks. Here, the authors show that HPF1 regulates the balance between ADP-ribose initiation and elongation through a dynamic interaction that accelerates the initiation rate o
Externí odkaz:
https://doaj.org/article/6078d4725d6843d48dcd1bc9e7b93b53
Autor:
Yilun Sun, Jiji Chen, Shar-yin N. Huang, Yijun P. Su, Wenjie Wang, Keli Agama, Sourav Saha, Lisa M. Jenkins, John M. Pascal, Yves Pommier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
TOP1 resolves DNA supercoils by forming cleavage complexes (TOP1cc) that are trapped by TOP1 inhibitors. Here the authors provide insights into the mechanistic understanding of TOP1cc PARylation, showing that inhibition of PARG results in stabilizati
Externí odkaz:
https://doaj.org/article/efd9b3f404b3443ca49e78b32652785a