Zobrazeno 1 - 10
of 979
pro vyhledávání: '"M. Coen"'
Systemic cytokines related to memory function 6–9 months and 12–15 months after SARS-CoV-2 infection
Autor:
A. Nuber-Champier, G. Breville, P. Voruz, I. Jacot de Alcântara, A. Cionca, G. Allali, P. H. Lalive, L. Benzakour, K.-O. Lövblad, O. Braillard, M. Nehme, M. Coen, J. Serratrice, J.-L. Reny, J. Pugin, I. Guessous, B. N. Landis, F. Assal, Julie Anne Péron
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Cognitive symptoms persisting beyond the acute phase of COVID-19 infection are commonly described for up to 2 years after infection. The relationship between cognitive performance, in particular episodic memory processes observed chronically
Externí odkaz:
https://doaj.org/article/a6ebd57f758b4b21871690dc9b4bed38
Autor:
Yujia (Susanna) Qiao, Terri L. Blackwell, Peggy M. Cawthon, Paul M. Coen, Steven R. Cummings, Giovanna Distefano, Samaneh Farsijani, Daniel E. Forman, Bret H. Goodpaster, Stephen B. Kritchevsky, Theresa Mau, Frederico G.S. Toledo, Anne B. Newman, Nancy W. Glynn
Publikováno v:
Journal of Sport and Health Science, Vol 13, Iss 5, Pp 621-630 (2024)
Background: Skeletal muscle energetics decline with age, and physical activity (PA) has been shown to offset these declines in older adults. Yet, many studies reporting these effects were based on self-reported PA or structured exercise interventions
Externí odkaz:
https://doaj.org/article/dc82c40127c14572a37112950489a8d5
Autor:
Yue Deng, Yuqi Lin, Siyu Chen, Yuhang Xiang, Hongjia Chen, Shuyuan Qi, Hyung Suk Oh, Biswajit Das, Gloria Komazin-Meredith, Jean M. Pesola, David M. Knipe, Donald M. Coen, Dongli Pan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Herpes simplex virus 1 (HSV-1) latent infection entails repression of viral lytic genes in neurons. By functional screening using luciferase-expressing HSV-1, we identify ten neuron-specific microRNAs potentially repressing HSV-1 neuronal re
Externí odkaz:
https://doaj.org/article/410423a0a7d541e0b07de9835ebc0df5
Autor:
Maddalena Parafati, Shelby Giza, Tushar S. Shenoy, Jorge A. Mojica-Santiago, Meghan Hopf, Legrand K. Malany, Don Platt, Isabel Moore, Zachary A. Jacobs, Paul Kuehl, Jason Rexroat, Gentry Barnett, Christine E. Schmidt, William T. McLamb, Twyman Clements, Paul M. Coen, Siobhan Malany
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Microphysiological systems provide the opportunity to model accelerated changes at the human tissue level in the extreme space environment. Spaceflight-induced muscle atrophy experienced by astronauts shares similar physiological changes to
Externí odkaz:
https://doaj.org/article/561fc3bd700b47deb2d2845634e19221
Autor:
Diego Hernández-Saavedra, J. Matthew Hinkley, Lisa A. Baer, Kelsey M. Pinckard, Pablo Vidal, Shinsuke Nirengi, Andrea M. Brennan, Emily Y. Chen, Niven R. Narain, Valerie Bussberg, Vladimir V. Tolstikov, Michael A. Kiebish, Christina Markunas, Olga Ilkayeva, Bret H. Goodpaster, Christopher B. Newgard, Laurie J. Goodyear, Paul M. Coen, Kristin I. Stanford
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109083- (2024)
Summary: Exercise mediates tissue metabolic function through direct and indirect adaptations to acylcarnitine (AC) metabolism, but the exact mechanisms are unclear. We found that circulating medium-chain acylcarnitines (AC) (C12-C16) are lower in act
Externí odkaz:
https://doaj.org/article/1fa864323c024e6ea418512ba98137e4
Autor:
M. Coen
Global terrorism is a double-edged threat to democracies. Physically, because of the number of people killed and wounded, structurally, because it threatens social peace and over-reaction tends to undermine our basic values. The authors of the chapte
Autor:
Han Chen, Ming F Lye, Christoph Gorgulla, Scott B Ficarro, Gregory D Cuny, David A Scott, Fan Wu, Paul W Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M Pesola, Sorin Draga, Jarrod A Marto, James M Hogle, Haribabu Arthanari, Donald M Coen
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011781 (2023)
Human cytomegalovirus (HCMV) is an important pathogen for which new antiviral drugs are needed. HCMV, like other herpesviruses, encodes a nuclear egress complex (NEC) composed of two subunits, UL50 and UL53, whose interaction is crucial for viral rep
Externí odkaz:
https://doaj.org/article/de5854a14a0246dc98346d4f72583da0
Autor:
Andrew Philp, Paul M. Coen
Publikováno v:
Experimental Gerontology, Vol 182, Iss , Pp 112304- (2023)
Externí odkaz:
https://doaj.org/article/1b65fd31365948f0b2220099944e046f
Autor:
Tumpa Dutta, Nidhi Kapoor, Meril Mathew, Suban S. Chakraborty, Nathan P. Ward, Nicolas Prieto-Farigua, Aimee Falzone, James P. DeLany, Steven R. Smith, Paul M. Coen, Gina M. DeNicola, Stephen J. Gardell
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112218- (2023)
Summary: Metabolic routing of nicotinamide (NAM) to NAD+ or 1-methylnicotinamide (MeNAM) has impacts on human health and aging. NAM is imported by cells or liberated from NAD+. The fate of 2H4-NAM in cultured cells, mice, and humans was determined by
Externí odkaz:
https://doaj.org/article/0ba5dbe77c3a4d6aa88795f4b3f2d9bd
Autor:
Gloria Griffante, Francesca Gugliesi, Selina Pasquero, Valentina Dell’Oste, Matteo Biolatti, Ari J. Salinger, Santanu Mondal, Paul R. Thompson, Eranthie Weerapana, Robert J. Lebbink, Jasper A. Soppe, Thomas Stamminger, Virginie Girault, Andreas Pichlmair, Gábor Oroszlán, Donald M. Coen, Marco De Andrea, Santo Landolfo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Citrullination is a posttranslational modification of arginines. Here, the authors show that HCMV infection increases citrullination of host and virus proteins to promote infection and that citrullinated interferon-inducible protein IFIT1 is impaired
Externí odkaz:
https://doaj.org/article/d9f89f1cfaed42dc92c156e171d58d7e