Zobrazeno 1 - 10
of 511
pro vyhledávání: '"M., Noto"'
Autor:
Jennifer M. Noto, M. Blanca Piazuelo, Judith Romero-Gallo, Alberto G. Delgado, Giovanni Suarez, Konstantina Akritidou, Miguel Girod Hoffman, Juan Carlos Roa, Cormac T. Taylor, Richard M. Peek
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTHelicobacter pylori-induced inflammation is the strongest known risk factor for gastric adenocarcinoma. Hypoxia-inducible factor-1 (HIF-1α) is a key transcriptional regulator of immunity and carcinogenesis. To examine the role of this mediat
Externí odkaz:
https://doaj.org/article/5ca1554c76e54c8382886b3806ff21b3
Autor:
Natalia M. Noto, Yazmin M. Restrepo, Hong W. Pang, Filipe Stoyell‐Conti, Crystal A. West, Robert C. Speth
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 1, Pp n/a-n/a (2023)
Abstract Angiotensin II analogue and β‐arrestin biased agonist TRV027 (Sarcosine1, d‐Alanine8‐Angiotensin (Ang) II; SD Ang II), developed by Trevena, Inc. in the early 2010s, brought hopes of a novel treatment for cardiovascular diseases, due
Externí odkaz:
https://doaj.org/article/6d33ae95def64aafad82a3c960739b14
Autor:
Samuel D.R. Dooyema, Jennifer M. Noto, Lydia E. Wroblewski, M. Blanca Piazuelo, Uma Krishna, Giovanni Suarez, Judith Romero-Gallo, Alberto G. Delgado, Richard M. Peek
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Chronic mucosal pathogens have evolved multiple strategies to manipulate the host immune response; consequently, microbes contribute to the development of >2 million cases of cancer/year. Gastric adenocarcinoma is the fourth leading cause of cancer-r
Externí odkaz:
https://doaj.org/article/f93259ca2dbb4a9897baa17e0061a47a
Autor:
Jennifer M. Noto, M. Blanca Piazuelo, Shailja C. Shah, Judith Romero-Gallo, Jessica L. Hart, Chao Di, James D. Carmichael, Alberto G. Delgado, Alese E. Halvorson, Robert A. Greevy, Lydia E. Wroblewski, Ayushi Sharma, Annabelle B. Newton, Margaret M. Allaman, Keith T. Wilson, M. Kay Washington, M. Wade Calcutt, Kevin L. Schey, Bethany P. Cummings, Charles R. Flynn, Joseph P. Zackular, Richard M. Peek Jr.
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
Gastric carcinogenesis is mediated by complex interactions among Helicobacter pylori, host, and environmental factors. Here, we demonstrate that H. pylori augmented gastric injury in INS-GAS mice under iron-deficient conditions. Mechanistically, thes
Externí odkaz:
https://doaj.org/article/7d198f5f9fa7400583ab84388b9c0680
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1202-1203 (2021)
Externí odkaz:
https://doaj.org/article/d971009f9b8d4d0bae0a2b211414f462
Autor:
Jennifer M. Noto, Joseph P. Zackular, Matthew G. Varga, Alberto Delgado, Judith Romero-Gallo, Matthew B. Scholz, M. Blanca Piazuelo, Eric P. Skaar, Richard M. Peek
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Helicobacter pylori is the strongest risk factor for gastric adenocarcinoma; however, most infected individuals never develop this malignancy. Strain-specific microbial factors, such as the oncoprotein CagA, as well as environmental conditio
Externí odkaz:
https://doaj.org/article/4e1d7e064e0343d7a2ef53ea353bd1c7
Akademický článek
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Autor:
Amber C. Beckett, John T. Loh, Abha Chopra, Shay Leary, Aung Soe Lin, Wyatt J. McDonnell, Beverly R.E.A. Dixon, Jennifer M. Noto, Dawn A. Israel, Richard M. Peek Jr, Simon Mallal, Holly M. Scott Algood, Timothy L. Cover
Publikováno v:
PeerJ, Vol 6, p e4803 (2018)
Helicobacter pylori requires genetic agility to infect new hosts and establish long-term colonization of changing gastric environments. In this study, we analyzed H. pylori genetic adaptation in the Mongolian gerbil model. This model is of particular
Externí odkaz:
https://doaj.org/article/7e2557821c3244d6b83bd4644d72624f
Publikováno v:
Clinical Science. 135:2619-2623
It is well-established that Ang-(1-7) counteracts the effects of Ang II in the periphery, while stimulating vasopressin release and mimicking the activity of Ang II in the brain, through interactions with various receptors. The rapid metabolic inacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef52d2123825b1189b8f0cdd7546f00
https://doi.org/10.1042/cs20211043
https://doi.org/10.1042/cs20211043
Autor:
Jennifer M. Noto, PhD
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 4, Pp 409-411 (2016)
Externí odkaz:
https://doaj.org/article/402c2edd76a24b5c92bd26c1b453bd29