Zobrazeno 1 - 10
of 13 698
pro vyhledávání: '"M., Hill"'
Autor:
Nicholas S. Caron, Lauren M. Byrne, Fanny L. Lemarié, Jeffrey N. Bone, Amirah E.-E. Aly, Seunghyun Ko, Christine Anderson, Lorenzo L. Casal, Austin M. Hill, David J. Hawellek, Peter McColgan, Edward J. Wild, Blair R. Leavitt, Michael R. Hayden
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-22 (2024)
Abstract Background Therapeutic approaches aimed at lowering toxic mutant huntingtin (mHTT) levels in the brain can reverse disease phenotypes in animal models of Huntington's disease (HD) and are currently being evaluated in clinical trials. Sensiti
Externí odkaz:
https://doaj.org/article/89b2e043ae1a4ef094cfbb9512ed2741
Publikováno v:
Evolution: Education and Outreach, Vol 17, Iss 1, Pp 1-19 (2024)
Abstract Background Understanding evolution is an important part of undergraduate biology education. Despite its importance, however, students often struggle to understand evolution, often holding preconceived notions of what evolution is. Here, we i
Externí odkaz:
https://doaj.org/article/9ebdf6e3abdd49a6bbb1956bc0bebb96
Autor:
Maria Rita Fabbrizi, Thomas J. Doggett, Jonathan R. Hughes, Emma Melia, Elizabeth R. Dufficy, Rhianna M. Hill, Amalia Goula, Ben Phoenix, Jason L. Parsons
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Ionising radiation (IR) is widely used in cancer treatment, including for head and neck squamous cell carcinoma (HNSCC), where it induces significant DNA damage leading ultimately to tumour cell death. Among these lesions, DNA double strand
Externí odkaz:
https://doaj.org/article/f8e0778641584cd48be2aa428cb231dc
Autor:
Lukas Rier, Natalie Rhodes, Daisie O Pakenham, Elena Boto, Niall Holmes, Ryan M Hill, Gonzalo Reina Rivero, Vishal Shah, Cody Doyle, James Osborne, Richard W Bowtell, Margot Taylor, Matthew J Brookes
Publikováno v:
eLife, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/52e68ac46deb4909aa28eff8dad56251
Publikováno v:
Data in Brief, Vol 56, Iss , Pp 110786- (2024)
Mucosal-associated invariant T (MAIT) cells represent a unique unconventional T cell population important in eliciting immunomodulatory responses in a range of diseases, including infectious diseases, autoimmunity and cancer. This innate-like T cell
Externí odkaz:
https://doaj.org/article/85aa6affd00e46bcae20680cfbafbc7b
Autor:
Ann Tivey, Rebecca J. Lee, Alexandra Clipson, Steven M. Hill, Paul Lorigan, Dominic G. Rothwell, Caroline Dive, Florent Mouliere
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101736- (2024)
Summary: Treatments for cancer patients are becoming increasingly complex, and there is a growing desire from clinicians and patients for biomarkers that can account for this complexity to support informed decisions about clinical care. To achieve pr
Externí odkaz:
https://doaj.org/article/cbd19a1dac464bc5b87b5c1a4245e025
Publikováno v:
Earth and Space Science, Vol 11, Iss 8, Pp n/a-n/a (2024)
Abstract Current understanding of the ammonia distribution in Jupiter's atmosphere is provided by observations from major ground‐based facilities and spacecraft, and analyzed with sophisticated retrieval models that recover high fidelity informatio
Externí odkaz:
https://doaj.org/article/a2ec82736cb648139bfa3e1eeea743d9
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 8, p e1012309 (2024)
The rapid development of vaccines against SARS-CoV-2 altered the course of the COVID-19 pandemic. In most countries, vaccinations were initially targeted at high-risk populations, including older individuals and healthcare workers. Now, despite subst
Externí odkaz:
https://doaj.org/article/8adde5fa12c74299982eabd39252f10e
Autor:
Alicia-Marie Conway, Simon P. Pearce, Alexandra Clipson, Steven M. Hill, Francesca Chemi, Dan Slane-Tan, Saba Ferdous, A. S. Md Mukarram Hossain, Katarzyna Kamieniecka, Daniel J. White, Claire Mitchell, Alastair Kerr, Matthew G. Krebs, Gerard Brady, Caroline Dive, Natalie Cook, Dominic G. Rothwell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Cancers of Unknown Primary (CUP) remains a diagnostic and therapeutic challenge due to biological heterogeneity and poor responses to standard chemotherapy. Predicting tissue-of-origin (TOO) molecularly could help refine this diagnosis, with
Externí odkaz:
https://doaj.org/article/d4bcd616a1c54d2c97e8ef0bccad3ec9
Autor:
Kristina Safar, Marlee M. Vandewouw, Julie Sato, Jasen Devasagayam, Ryan M. Hill, Molly Rea, Matthew J. Brookes, Margot J. Taylor
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Optically pumped magnetometers (OPMs) offer a new wearable means to measure magnetoencephalography (MEG) signals, with many advantages compared to conventional systems. However, OPMs are an emerging technology, thus characterizing and replic
Externí odkaz:
https://doaj.org/article/7fe2474f77474c55aa15c9b330fd6f42