Zobrazeno 1 - 10
of 1 647
pro vyhledávání: '"M., Anders"'
Autor:
Shefali Chauhan, Emily Lian, Iman Habib, Qianqian Liu, Nicole M. Anders, Megan M. Bugg, Noah C. Federman, Joel M. Reid, Clinton F. Stewart, Tristan Cates, Joel E. Michalek, Charles Keller
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Rhabdomyosarcoma (RMS) is the most common childhood soft tissue sarcoma. For the alveolar subtype (ARMS), the presence of the PAX3::FOXO1 fusion gene and/or metastases are strong predictors of poor outcome. Metastatic PAX3::FOXO1 + ARMS ofte
Externí odkaz:
https://doaj.org/article/f0d777b3277b40b58dcedcf300719a97
Autor:
Maggie Li, Barbara J. Smith, Jaeyeun Lee, Jennifer Petr, Nicole M. Anders, Robyn Wiseman, Michelle A. Rudek, Richard F. Ambinder, Prashant J. Desai
Publikováno v:
Infectious Agents and Cancer, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background Antiviral therapies that target herpesviruses are clinically important. Nelfinavir is a protease inhibitor that targets the human immunodeficiency virus (HIV) aspartyl protease. Previous studies demonstrated that this drug could a
Externí odkaz:
https://doaj.org/article/5c85366898714cc8a83db117ba7dffca
Publikováno v:
Earth Surface Dynamics, Vol 11, Pp 849-863 (2023)
Glaciers are sensitive to temporal climate variability. Glacier sensitivity to spatial variability in climate has been much less studied. The Olympic Mountains of Washington state, USA, experience a pronounced orographic precipitation gradient, with
Externí odkaz:
https://doaj.org/article/a9822a5b8fc24b59a939725625a35e08
Autor:
Amanda B. Kagan, Dominique A. Garrison, Nicole M. Anders, Jonathan A. Webster, Sharyn D. Baker, Srinivasan Yegnasubramanian, Michelle A. Rudek
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 8, Pp 1309-1322 (2023)
Abstract Although DNA methyltransferase inhibitors (DNMTis), such as azacitidine and decitabine, are used extensively in the treatment of myelodysplastic syndromes and acute myeloid leukemia, there remain unanswered questions about DNMTi's mechanism
Externí odkaz:
https://doaj.org/article/2558cdc7ea7d4ba6b1738378115c452f
Autor:
Henry T. Hsueh, Renee Ti Chou, Usha Rai, Wathsala Liyanage, Yoo Chun Kim, Matthew B. Appell, Jahnavi Pejavar, Kirby T. Leo, Charlotte Davison, Patricia Kolodziejski, Ann Mozzer, HyeYoung Kwon, Maanasa Sista, Nicole M. Anders, Avelina Hemingway, Sri Vishnu Kiran Rompicharla, Malia Edwards, Ian Pitha, Justin Hanes, Michael P. Cummings, Laura M. Ensign
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Sustained drug delivery strategies have many potential benefits for treating a range of diseases, particularly chronic diseases that require treatment for years. For many chronic ocular diseases, patient adherence to eye drop dosing regimens
Externí odkaz:
https://doaj.org/article/7e5564fd12a045e4b4626040941ea3e5
Autor:
Jing Zhang, Deepti Sharma, Aumreetam Dinabandhu, Jaron Sanchez, Brooks Applewhite, Kathleen Jee, Monika Deshpande, Miguel Flores-Bellver, Ming-Wen Hu, Chuanyu Guo, Shaima Salman, Yousang Hwang, Nicole M. Anders, Michelle A. Rudek, Jiang Qian, M. Valeria Canto-Soler, Gregg L. Semenza, Silvia Montaner, Akrit Sodhi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Many patients with diabetic eye disease respond inadequately to anti-VEGF therapies, implicating additional vasoactive mediators in its pathogenesis. We demonstrate that levels of angiogenic proteins regulated by HIF-1 and -2 remain elevated in the e
Externí odkaz:
https://doaj.org/article/208f02b363f54dcab967e446a3a95992
Autor:
J. Lai, A. M. Anders
Publikováno v:
Earth Surface Dynamics, Vol 9, Pp 845-859 (2021)
Climate has been viewed as a primary control on the rates and patterns of glacial erosion, yet our understanding of the mechanisms by which climate influences glacial erosion is limited. We hypothesize that climate controls the patterns of glacial er
Externí odkaz:
https://doaj.org/article/21dcd3d66f2a46a3b9aee7cabf6513a7
Autor:
Shaima Salman, David J. Meyers, Elizabeth E. Wicks, Sophia N. Lee, Emmanuel Datan, Aline M. Thomas, Nicole M. Anders, Yousang Hwang, Yajing Lyu, Yongkang Yang, Walter Jackson III, Dominic Dordai, Michelle A. Rudek, Gregg L. Semenza
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
Hepatocellular carcinoma (HCC) is a major cause of cancer mortality worldwide and available therapies, including immunotherapies, are ineffective for many patients. HCC is characterized by intratumoral hypoxia, and increased expression of hypoxia-ind
Externí odkaz:
https://doaj.org/article/93de6172546f4b1dba403323cea12053
Autor:
J. Buday, J. Albrecht, G. Podgorná, T. Mareš, T.H. Le, V. Čapek, J. Mahrík, M. Pol, J. Raboch, M. Anders
Publikováno v:
Brain Stimulation, Vol 13, Iss 6, Pp 1631-1638 (2020)
Introduction: A high seizure threshold (ST) is an impeding factor in certain patients, potentially preventing a successful electroconvulsive therapy (ECT) treatment. Several pharmacological and non-pharmacological methods have been put forward to aug
Externí odkaz:
https://doaj.org/article/eef5e414e1fe4b4699f348922faa6a10
Autor:
Amanda B. Kagan, Blake S. Moses, Bryan T. Mott, Ganesha Rai, Nicole M. Anders, Michelle A. Rudek, Curt I. Civin
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Acute myeloid leukemia (AML) remains a devastating disease, with low cure rates despite intensive standard chemotherapy regimens. In the past decade, targeted antileukemic drugs have emerged from research efforts. Nevertheless, targeted therapies are
Externí odkaz:
https://doaj.org/article/2cf6566fed2a4ca3b0fec12ce23940fd