Zobrazeno 1 - 10
of 264
pro vyhledávání: '"M-F Poupon"'
Autor:
Didier Decaudin, Ch. Guyader, Paul-Henri Cottu, L. De Plater, M.-F. Poupon, Anne Vincent-Salomon, David Gentien, Franck Assayag, P. de Cremoux, Virginie Dangles-Marie, Narjesse Karboul, Sophie Chateau-Joubert, Elisabetta Marangoni, J.J. Fontaine, Séverine Alran, P. Boudou-Rouquette, C. Elbaz
Publikováno v:
Breast Cancer Research and Treatment. 133:595-606
Resistance to endocrine therapy is a major complication of luminal breast cancer and studies of the biological features of hormonal resistance are limited by the lack of adequate preclinical models. The aim of this study is to establish and character
Autor:
P. de Cremoux, Paul Cottu, Franck Assayag, Anthony Laugé, Brigitte Sigal-Zafrani, Dominique Stoppa-Lyonnet, Elisabetta Marangoni, M.-F. Poupon, Charlotte Guyader, Anne Vincent-Salomon, Didier Decaudin, Rachel Brough, Christopher J. Lord, L. De Plater, J.J. Fontaine, Alan Ashworth
Publikováno v:
British Journal of Cancer
Germline BRCA2 mutations in female carriers confer a cumulative breast cancer risk at age 70 years of 49% (95% CI: 40–57%), an ovarian cancer risk of 18% (95% CI: 13–23%), and a moderate increased risk of pancreatic cancer (Chen and Parmigiani, 2
Autor:
G de Pinieux, Nicolas Lecomte, M.-F. Poupon, Florence Smadja-Joffe, Elisabetta Marangoni, Didier Decaudin, Christine Chomienne, L. Durand
Publikováno v:
British Journal of Cancer
CD44 is a marker of tumour-initiating cells and is upregulated in invasive breast carcinoma; however, its role in the cancer progression is unknown. Here, we show that antibody-mediated CD44-targeting in human breast cancer xenografts (HBCx) signific
Autor:
Rosette Lidereau, F. Arvelo, A. Sihassen, J. Bara, Bernard Dutrillaux, F. Poirson-Bichat, M.-F. Poupon, Anne-Marie Dutrillaux, Marie-Emmanuelle Legrier, Karine Boyé, Françoise Apiou, G. de Pinieux
Publikováno v:
Pathologie Biologie. 51:1-4
Resume Le cancer de la prostate est en frequence le deuxieme cancer chez l’homme. Souvent, initialement hormono-dependant, la perte de reponse aux traitements anti-androgeniques survient au cours de la progression tumorale, traduisant l’emergence
Autor:
Jean-Louis Fischel, Pierre Laurent-Puig, Nicolas Magné, Patricia Formento, M.-F. Poupon, Dubreuil A, Gérard Milano
Publikováno v:
British Journal of Cancer
ZD1839 (‘Iressa’) is an orally active, selective epidermal growth factor receptor–tyrosine kinase inhibitor (EGFR–TKI), which blocks signal transduction pathways implicated in proliferation and survival of cancer cells, and other host-depende
Autor:
Rui Bras-Gonçalves, P. Soulie, M.-F. Poupon, Christophe Rosty, Pierre Laurent-Puig, Bernard Dutrillaux
Publikováno v:
British Journal of Cancer
Biological parameters influencing the response of human colorectal cancers (CRCs) to CPT-11, a topoisomerase 1 (top1) inhibitor, were investigated using a panel of nine CRCs xenografted into nude mice. CRC xenografts differed in their p53 status (wt
Autor:
M.-F. Poupon
Publikováno v:
Annales de Pathologie. 26:51-53
Publikováno v:
Proceedings of the National Academy of Sciences. 91:286-290
It is generally accepted that primary tumors become heterogeneous as a consequence of tumor-cell genetic instability. Clonal dominance has been shown to occur in some experimental models allowing a subpopulation of cells to overgrow the primary heter
Publikováno v:
Oncology reports. 3(1)
High aerobic glycolysis is frequent in cancers. Glucose phosphorylation is under control of hexokinase which is found in the cytosol or bound to mitochondria. Glycolysis parameters (glucose, pyruvate and lactate) and hexokinase were evaluated in extr
Autor:
T. Le Chevalier, Rodrigo Arriagada, F. Arvelo, Anne-Françoise Goguel, Gérard Lizard, Y. Bourgeois, M. F. Poupon
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 120:17-23
Small-cell lung carcinomas (SCLC) are highly responsive to various chemotherapies. However only a minority of patients benefit from long survival. SCLC patients treated at the Institut Gustave Roussy received a combined chemotherapy (CCAV) including