Zobrazeno 1 - 10
of 25
pro vyhledávání: '"M-C. Laplace"'
Publikováno v:
Biochemical Journal. 303:227-231
Binding of 125I-thrombin to human umbilical vein endothelial cells (HUVECs) was specifically displaced by the synthetic tetradecapeptide SFLLRNPNDKYEPF, named thrombin receptor agonist peptide (TRAP), which has recently been described as a peptide mi
Autor:
P.-Y. Gueugniaud, G. Fournier, L. Besson, J.-L. Caillot, E. J. Voiglio, A. Ndiaye, Mireille Chiron, M.-C. Laplace
Publikováno v:
Journal Européen des Urgences. 20:34-35
Autor:
Paul J. Schaeffer, Jean-Marc Herbert, Danielle Gully, A Bernat, V. Prabonnaud, L. Lespy, M C Laplace
Publikováno v:
Journal of cardiovascular pharmacology. 31(4)
The novel compound SR142948A was compared with SR48692 as an antagonist of neurotensin-induced cardiovascular effects both in vitro and in vivo. SR142948A inhibited [125I]-neurotensin binding [median inhibitory concentration (IC50) = 0.24 +/- 0.01 nM
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 269(2)
Thienopyridine compounds, including ticlopidine and clopidogrel, have been found to selectively inhibit adenosine 5' diphosphate (ADP)-induced platelet aggregation and adenylyl cyclase ex vivo, but the mechanism of their antiplatelet action remains t
Autor:
J M, Herbert, L, Fraisse, A, Bachy, G, Valette, P, Savi, M C, Laplace, J, Lassalle, B, Roche, A, Lale, P E, Keane
Publikováno v:
Journal of lipid mediators. 8(1)
SR 27388 (N-(2-dimethylaminoethyl)-N-(3-pyridinylmethyl[4-(3,5-di(tert- butyl)-4-hydroxylphenyl)thiazol-2-yl]amine) is a potent and competitive antagonist of the binding of [3H]PAF to its receptor on rabbit platelets exhibiting an equilibrium inhibit
Publikováno v:
Journal of lipid mediators. 7(1)
SR 27417, the first member of a newly developed PAF antagonist series, fully and competitively displaced [3H]PAF from its high-affinity binding sites on washed rabbit and human platelets with Ki values of 57 +/- 0.02 and 50 +/- 0.8 pM (n = 3), respec
Autor:
C. Volle-Challier, M. Trombe, G. Morin, Françoise Bono, I. Blanc, M-C. Laplace, Dol, C. Labouret, G. Gueguen
Publikováno v:
Journal of Clinical Oncology. 28:e13524-e13524
e13524 Background: A critical step in tumor progression is the interaction of malignant and stromal cells via paracrine mechanisms. Among these stromal cells, cancer-associated fibroblasts (CAFs), ...
Publikováno v:
Journal of lipid mediators. 5(1)
Pharmacodynamics of SR 27417, a novel, specific platelet-activating factor (PAF) antagonist was monitored with ex vivo PAF-induced platelet aggregation in the rabbit. Single per os administration of SR 27417 (5 mg/kg) resulted in complete inhibition
Autor:
J M, Herbert, A, Bernat, G, Valette, V, Gigo, A, Lale, M C, LaPlace, L, Lespy, P, Savi, J P, Maffrand, G, Le Fur
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 259(1)
SR 27417 [N-(2-dimethylamino ethyl)-N-(3-pyridinyl methyl)[4- (2,4,6-triisopropylphenyl) thiazol-2-yl]amine] is the first member of a newly developed platelet-activating factor (PAF) antagonist series. It is a highly potent, competitive and selective
Autor:
G, Bagou, M C, Laplace, B, Coronel, M C, Prud'hon, H J, Clement, D, Muguet, J F, Moskovtchenko
Publikováno v:
Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression. 32(2)
Laparoscopy without an important surgical act was executed in twenty patients. Anaesthetic protocol associated propofol, alfentanil and vecuronium. This protocol meet conditions for ambulatory patients. Only three were not suited to leave hospital si