Zobrazeno 1 - 10
of 201
pro vyhledávání: '"M van Roon"'
Autor:
George E. Ghanim, Zala Sekne, Sebastian Balch, Anne-Marie M. van Roon, Thi Hoang Duong Nguyen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Telomerase is a ribonucleoprotein (RNP) enzyme that extends telomeric repeats at eukaryotic chromosome ends to counterbalance telomere loss caused by incomplete genome replication. Human telomerase is comprised of two distinct functional lob
Externí odkaz:
https://doaj.org/article/ffd74c388d224797b9d2eee3e0472c93
Autor:
Balewgizie S. Tegegne, M. Abdullah Said, Alireza Ani, Arie M. van Roon, Sonia Shah, Eco J. C. de Geus, Pim van der Harst, Harriëtte Riese, Ilja M. Nolte, Harold Snieder
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Low heart rate variability (HRV) has been widely reported as a predictor for increased mortality. However, the molecular mechanisms are poorly understood. Therefore, this study aimed to identify novel genetic loci associated with HRV and ass
Externí odkaz:
https://doaj.org/article/7dba2ffda68c443ab3b1e41624dac6e3
Predicting recurrence of depression using cardiac complexity in individuals tapering antidepressants
Autor:
Sandip V. George, Yoram K. Kunkels, Arnout Smit, Marieke Wichers, Evelien Snippe, Arie M. van Roon, Harriëtte Riese
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract It is currently unknown whether the complexity and variability of cardiac dynamics predicts future depression and whether within-subject change herein precedes the recurrence of depression. We tested this in an innovative repeated single-sub
Externí odkaz:
https://doaj.org/article/1a17594994c14d41a4126706d7d71441
Autor:
Zekai Chen, Siqi Wang, Zhen He, Balewgizie S. Tegegne, Arie M. van Roon, Judith C. S. Holtjer, Pim van der Harst, Harold Snieder, Chris H. L. Thio
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundIt is unclear how cardiac autonomic function, as indicated by heart rate (HR), heart rate variability (HRV), HR increase during exercise, and HR recovery after exercise, is related to blood pressure (BP). We aimed to examine the observation
Externí odkaz:
https://doaj.org/article/d14b032009654d0dae3a748355e5289a
Autor:
Yoram K. Kunkels, Harriëtte Riese, Stefan E. Knapen, Rixt F. Riemersma - van der Lek, Sandip V. George, Arie M. van Roon, Robert A. Schoevers, Marieke Wichers
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Early-warning signals (EWS) have been successfully employed to predict transitions in research fields such as biology, ecology, and psychiatry. The predictive properties of EWS might aid in foreseeing transitions in mood episodes (i.e. recur
Externí odkaz:
https://doaj.org/article/5cfa0773b2484fc88817992a959c09ec
Autor:
Berend G. C. Slijkhuis, David J. Liesker, Sherilyn A. C. Konter, Annet Possel-Nicolai, Reinoud P. H. Bokkers, Niek H. J. Prakken, Elisabeth Brouwer, Riemer H. J. A. Slart, Arie M. van Roon, Ben R. Saleem, Douwe J. Mulder
Publikováno v:
Diagnostics, Vol 13, Iss 10, p 1669 (2023)
Inflammatory abdominal aortic aneurysms (iAAA) are a form of noninfectious aortitis in patients with abdominal aortic aneurysms (AAA). Ultrasound could help to detect iAAA early. This retrospective observational study assessed the potential of using
Externí odkaz:
https://doaj.org/article/fa5a9660fa224b8ba095b03586d202ea
Autor:
Yehya Al-Adwi, Isabella M. Atzeni, Berber Doornbos-van der Meer, Amaal Eman Abdulle, Anniek M. van Roon, Alja Stel, Harry van Goor, Andries J. Smit, Johanna Westra, Douwe J. Mulder
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 794 (2023)
Raynaud’s Phenomenon (RP) leading to repetitive ischemia and reperfusion (IR) stress, is the first recognizable sign of systemic sclerosis (SSc) leading to increased oxidative stress. High-mobility group box-1 (HMGB1) is a nuclear factor released b
Externí odkaz:
https://doaj.org/article/75988b3ecbe04fab83e04140eaa80168
Autor:
Deli Zhang, Xu Hu, Jin Li, Jia Liu, Luciënne Baks-te Bulte, Marit Wiersma, Noor-ul-Ann Malik, Denise M. S. van Marion, Marziyeh Tolouee, Femke Hoogstra-Berends, Eva A. H. Lanters, Arie M. van Roon, Antoine A. F. de Vries, Daniël A. Pijnappels, Natasja M. S. de Groot, Robert H. Henning, Bianca J. J. M. Brundel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Atrial fibrillation (AF) is accompanied by a detrimental loss of functional cardiomyocytes. Here, Zhang et al. show that AF-induced cardiomyocyte dysfunction is a consequence of DNA damage-mediated PARP1 activation, which leads to depletion of NAD+ a
Externí odkaz:
https://doaj.org/article/9f755550b82b4522aecca3e20910e91e
Autor:
Annika M. van Roon, Egle Rapaliute, Xhelil Koleci, Violeta Muñoz, Mathilde Mercat, Céline Faverjon, Inge M. G. A. Santman-Berends, Mirjam Nielen, Simon J. More, David Graham, Maria Guelbenzu-Gonzalo, Aurélien Madouasse, Christine Fourichon, Gerdien van Schaik
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Various European Member States have implemented control or eradication programmes for endemic infectious diseases in cattle. The design of these programmes varies between countries and therefore comparison of the outputs of different control programm
Externí odkaz:
https://doaj.org/article/94a296be498c44289e238449f55a3d2f
Autor:
Esmée M. Ettema, Johanna Kuipers, Martijn van Faassen, Henk Groen, Arie M. van Roon, Joop D. Lefrandt, Ralf Westerhuis, Ido P. Kema, Harry van Goor, Ron T. Gansevoort, Carlo A. J. M. Gaillard, Casper F. M. Franssen
Publikováno v:
BMC Nephrology, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Intradialytic hypotension is a common complication of hemodialysis. The Hemocontrol biofeedback system, improving intradialytic hemodynamic stability, is associated with an initial transient increase in plasma sodium levels. Incre
Externí odkaz:
https://doaj.org/article/5eb9ce313b4a4026b26ff2b310c2ad75