Zobrazeno 1 - 10
of 26
pro vyhledávání: '"M Z, Howard"'
Autor:
J Chen, N M Dunlop, Jiaqi Huang, Y Gao, O M Z Howard, X-w Bian, Wanghua Gong, Keqiang Chen, Ji Ming Wang
Publikováno v:
British Journal of Cancer
Background: The G-protein-coupled formylpeptide receptor (FPR) that mediates chemotaxis of phagocytic leucocytes induced by bacterial and host-derived chemotactic peptides is selectively expressed by highly malignant human gliomas and contributes to
Publikováno v:
Annals of the New York Academy of Sciences. 917:19-28
Opioids are known to suppress a number of elements of the immune response, including antimicrobial resistance, antibody production, and delayed-type hypersensitivity. Phagocytic cells may be particularly susceptible to opioid administration, since re
Publikováno v:
Inflammation Research. 49:744-755
Objective and design: To demonstrate the role of bile acids in immune modulation we examined the ability of select bile acids to inhibit leukocyte migration and chemoattractant receptor function.¶Materials: To elucidate this mechanism, we employed p
Publikováno v:
Immunological Reviews. 177:68-78
"... It is likely that the leukocyte granulations are in fact secretory products, which the cell dissolves and spreads to the environment as needed", Paul Ehrlich, 1900. Neutrophil granules have long been recognized as mediators of innate host defens
Autor:
Qian Chen, Oleg Chertov, S. N. Bykovskaia, O. M. Z. Howard, D. Yang, J. I. Shogan, M. Anderson, J. M. Schröder, M. J. Buffo, Ji Ming Wang, Joost J. Oppenheim
Publikováno v:
Science. 286:525-528
Defensins contribute to host defense by disrupting the cytoplasmic membrane of microorganisms. This report shows that human β-defensins are also chemotactic for immature dendritic cells and memory T cells. Human β-defensin was selectively chemotact
Autor:
O. M. Z. Howard, B. Erlichman
Publikováno v:
Cytokine. 11:476-484
Tumour necrosis factor receptor (TNFR) superfamily members play critical roles in the regulation of cell proliferation and death. One member of the TNFR superfamily, CD27, is unique because it is the only covalently linked homodimer in the family. CD
Publikováno v:
Journal of Clinical Immunology. 19:280-292
Despite the youth of the chemokine field, many antagonists of chemokine function have already been identified and tested at the preclinical level. These include neutralizing antibodies, peptidyl and non-peptidyl antagonists and non-specific immunosup
Autor:
Jim A. Turpin, J. J. Oppenheim, Michael Grimm, William G. Rice, Christopher J. Michejda, Robert Blumenthal, Nadya I. Tarasova, O. M. Z. Howard, Thomas Korte
Publikováno v:
Journal of Leukocyte Biology. 64:6-13
The intersection of the HIV and the chemokine fields began with the observation that HIV entry into cells could be blocked by certain chemokines. Subsequent work showed that HIV entry is dependent on the presence of specific chemokine receptors. Thes
Autor:
Michael Grimm, J. H. Resau, Hydar Ali, Ricardo M. Richardson, Adit Ben-Baruch, Dennis D. Taub, O. M. Z. Howard, Joost J. Oppenheim, Ralph Snyderman, Ji Ming Wang
Publikováno v:
The Journal of Experimental Medicine
An intact chemotactic response is vital for leukocyte trafficking and host defense. Opiates are known to exert a number of immunomodulating effects in vitro and in vivo, and we sought to determine whether they were capable of inhibiting chemokine-ind
Autor:
Hallgeir Rui, Robert A. Kirken, M. Kawamura, Maria Grazia Malabarba, John J. O'Shea, O. M. Z. Howard, William L. Farrar
Publikováno v:
Cytokine. 7:689-700
A number of cytokines and growth factors use the JAK-STAT pathway to signal from the cell membrane to the nucleus. While homodimerizing cytokine receptors may transmit signal via a single form of JAK (i.e. growth hormone receptors), several multicomp