Zobrazeno 1 - 10
of 25
pro vyhledávání: '"M Z, Guan"'
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 36(3)
In order to improve the biological activity and reduce the side effects and toxicity, a series of novel estrogen receptor antagonists were designed.The key triphenylethylene intermediates were obtained by the McMurry reaction. The target compounds we
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 31(1)
Treatment of rats with (+/-) gossypol 80 mg.kg-1 or (-) gossypol 40 mg.kg-1 on day 6-9 of gestation terminated early pregnancy. However, (+) gossypol at the dosage of 40 mg.kg-1 was found to have no effect on gestation. (-) Gossypol at a concentratio
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 29(8)
Synthetic GRP and its analogues, GRP-NH2, [Glu7.9.14 Lys6.10] GRP (6-14), [Phe14] GRP (5-14) and [Phe14] GRP, at the concentration of 0.05 mmol.L-1 were shown to have stimulatory effect on LH secretion in cultured mouse pituitary in vitro. The luteot
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 29(6)
Twenty peptides containing hydroxy-amino acids have been synthesized manually by stepwise solid-phase procedure. The chloromethyl resin and MBHA resin were used as solid supports. A new reagent of 0.5 mol.L-1 DDSi/1.5 mol.L-1 phenol/DCM was applied f
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 28(6)
After i.v. injection of dihydroepiandrosterone sulfate (DHA-S) at 20 or 40 mg/kg to female rats on day 19 of gestation, the tension and hydroxyproline level of uterine cervix were decreased obviously. However, DHA-S at 10 mg/kg showed no effect on th
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 26(1)
Eleven peptides containing hydroxy-amino-acid have been synthesized manually by stepwise solid-phase method. Three of them were started on BHA-resin, the others on Merrifield-resin. TFMSA/TFA/p-cresol were used as cleaving reagent in all peptide-resi
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 26(12)
Diphenoxylate hydrochloride (R1132) at concentrations of 10 and 20 micrograms/ml or dl-15 methyl-PGF2 alpha methyl ester (PG05) at levels of 5 and 10 micrograms/ml was shown to have no effect on progesterone secretion by luteal cells in vitro in the
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 25(2)
Oral or subcutaneous administration of yuehchukene to female mice at the dosage of 2 or 4 mg/kg.d on day 1-3 of gestation resulted in 100% anti-implantation effect. However, yuehchukene at 4 mg/kg.d was found to have no anti-implantation effect in ha
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Akademický článek
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