Výsledky vyhledávání - "M Z, Gorgoshidze"

Thermostability of rat sarcoma M1 procollagen solutions, procollagen fibers and whole tissues

Autor: Liana Kikalishvili, Maya Kiladze, J. Monaselidze, M. Z. Gorgoshidze, Manana Ramishvili

Publikováno v: Journal of Thermal Analysis and Calorimetry. 142:1561-1565

In close to equilibrium conditions (1° per 400 min), the DSC measurements demonstrated that the melting parameters of white rat sarcoma M1 procollagen equaled to Tm = 34.4 °C and ΔTm = 2.7°, and the same parameters of fibers reconstructed from th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ef01bbaf9cf697e1549595728f380ba
https://doi.org/10.1007/s10973-020-09332-4

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Thermal stability of blood plasma proteins of breast cancer patients, DSC study

Autor: L. Kikalishvili, M. Ramishvili, T Lezhava, P. Khorava, G. Nemsadze, Maya Kiladze, M. Z. Gorgoshidze, J. Monaselidze

Publikováno v: Journal of Thermal Analysis and Calorimetry. 120:501-505

The thermodynamic stability of blood plasma main proteins of 17 patients (32–72-year-old women) with preliminary diagnosis of ductal carcinoma was studied. We had only one case, when a tissue with size

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37f281a522db232aeea7c353bddedbbb
https://doi.org/10.1007/s10973-015-4426-2

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SIMULTANEOUS EFFECTS OF Cd(II) AND Pb(II) IONS AND γ-IRRADIATION ON STABILITY OF Spirulina platensis

Autor: E. Gelagutashvili, E. M. Lomidze, J. Monaselidze, M. Z. Gorgoshidze, N. Bagdavadze

Publikováno v: European Chemical Bulletin. 8:38

Effect of toxic metal ions Cd(II) and Pb(II) on cyanobacterium (blue-green algae) Spirulina platensis intact cells have been studied with optical and differential scanning microcalorimetry (DSC) methods after 7.2 kGy 137 Cs gamma irradiation and with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8db955c5cc5af183e8c1f420788c7925
https://doi.org/10.17628/ecb.2019.8.38-43

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Zn Ions Change Binding Mode of TOEPyP4 with DNA and Cause DNA Transition from B to C and Zn-Like Conformations

Autor: M. Z. Gorgoshidze, D. G. Khachidze, J. Monaselidze, H. L. Margaryan, Eugene Kiziria, Vasil G. Bregadze, Nune Hakobyan, Maya Kiladze

Publikováno v: American Journal of Analytical Chemistry. :744-748

It is known that at low concentrations of TMPyP4, this porphyrin predominantly intercalates between GC pairs at GC-rich sites of duplex DNA and G-quadruplexes of various constructions, and stabilizes these structures. However, there are still some ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44313e4f88b2ca9ce0cdbe1225603c75
https://doi.org/10.4236/ajac.2013.412090

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CD and DSC Investigation of Individual and Complex Influence of Meso-Tetra(4-Oxiethylpyridil) Porphyrin (TOEPyP4) and Its Zn-Complex on DNA

Autor: E. M. Lomidze, D. G. Khachidze, H. L. Margaryan, Nune Hakobyan, Maya Kiladze, Evgeni Kiziria, M. Z. Gorgoshidze, J. Monaselidze

Publikováno v: American Journal of Analytical Chemistry. :698-703

CD spectra of (DNA-TOEPyP4) + ZnTOEPyP4, (DNA-ZnTOEPyP4) + TOEPyP4, and DNA + (TOEPyP4-ZnTO- EPyP4) complexes have been studied. It is shown that CD spectra of these triple complexes significantly differ from the DNA-TOEPyP4 and DNA-ZnTOEPyP4 double

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6efd2f3000d82e9d15707e85471f71ee
https://doi.org/10.4236/ajac.2012.310092

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Microcalorimetric study of DNA–Cu(II)TOEPyP(4) porphyrin complex

Autor: Theimuraz A. Lezhava, E. M. Lomidze, M. Z. Gorgoshidze, J. Monaselidze, D. G. Khachidze, Maya Kiladze, Vasil G. Bregadze

Publikováno v: Journal of Thermal Analysis and Calorimetry. 108:127-131

The influence of new water soluble cationic metalloporphyrin Cu(II)TOEPyP(4) (meso-tetra-(4-N-oxyethylpyridyl)), analogue of Cu(II)TMPyP(4), on thermodynamic stability of DNA at various molar ratios of r = porphyrin/DNA b.p. (0

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11ef58823ca0e17eb2e1aae0f9ea3243
https://doi.org/10.1007/s10973-011-1669-4

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Microcalorimetric Investigation of DNA, poly(dA)poly(dT) and poly[d(A-C)]poly[d(G-T)] Melting in the Presence of Water Soluble (Meso tetra (4 N oxyethylpyridyl) Porphyrin) and its Zn Complex

Autor: J. Monaselidze, G. Majagaladze, Yeva B. Dalyan, Vardanyan Vi, Sh Barbakadze, D. G. Khachidze, S. G. Haroutiunian, M. Z. Gorgoshidze, Y. Kalandadze

Publikováno v: Journal of Biomolecular Structure and Dynamics. 25:419-424

Thermodynamic parameters of melting process (DeltaHm, Tm, DeltaTm) of calf thymus DNA, poly(dA)poly(dT) and poly(d(A-C)).poly(d(G-T)) were determined in the presence of various concentrations of TOEPyP(4) and its Zn complex. The investigated porphyri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac0bdaf44596fcddfae3e515f6e77a1
https://doi.org/10.1080/07391102.2008.10507190

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Conformations of DNA in the presence of nanomole concentrations of Co+2 ions and mezo-tetra(4-N-oxyethylpiridil) porphyrin

Autor: Nune Hakobyan, D. G. Khachidze, H. L. Margaryan, M. Z. Gorgoshidze, Maya Kiladze, Eugene Kiziria, J. Monaselidze, Vasil G. Bregadze

Publikováno v: Journal of biomolecular structuredynamics. 33(2)

Conformation changes of calf thymus DNA induced by nanomole concentrations of Co(+2) and TOEPyP4 and influence of this ion on porphyrin binding mode with DNA duplex were studied at two NaCl concentrations (10 and 100 mM) using circular dichroism spec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bf778b352cfa802c0ee1f25ab15d5d
https://pubmed.ncbi.nlm.nih.gov/24428403

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Effect of the peptide bronchogen (Ala-Asp-Glu-Leu) on DNA thermostability

Autor: D. G. Khachidze, E. M. Lomidze, T Lezhava, J. Monaselidze, Tinatin Jokhadze, M. Z. Gorgoshidze, V. Kh. Khavinson

Publikováno v: Bulletin of experimental biology and medicine. 150(3)

Thermodynamic parameters of DNA melting in the presence of a peptide bronchogen in various concentrations were estimated on a differential scanning microcalorimeter. Bronchogen was shown to serve as a DNA-stabilizing agent. Bronchogen increased the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0480f9d462dc7937c5dd10953ddf5e04
https://pubmed.ncbi.nlm.nih.gov/21240358

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