Zobrazeno 1 - 10
of 2 957
pro vyhledávání: '"M Y, Chen"'
Autor:
Jessy John, Samantha M. Y. Chen, Rachel A. Woolaver, Huaibin Ge, Monika Vashisht, Ziyu Huang, Zhangguo Chen, Jing H. Wang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment; however, the responses to ICI treatment are highly variable in different individuals and the underlying mechanisms remain poorly understood. Here, we employed a mouse squamous
Externí odkaz:
https://doaj.org/article/d37efbe2fd27490894a7e6687b1d22c5
Autor:
Samantha M. Y. Chen, Vince Popolizio, Rachel A. Woolaver, Huaibin Ge, Alexandra L. Krinsky, Jessy John, Etienne Danis, Yao Ke, Yonatan Kramer, Li Bian, Andrew G. Nicklawsky, Dexiang Gao, Silvia Liu, Zhangguo Chen, Xiao-jing Wang, Jing H. Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-24 (2022)
Abstract Background While immune checkpoint inhibitors (ICI) were approved for head and neck squamous cell carcinomas (HNSCCs), the response rate remains relatively low. Mechanisms underlying ICI unresponsiveness versus sensitivity are not fully unde
Externí odkaz:
https://doaj.org/article/fe3ccf84926d43a5bceb19b100126efd
Autor:
Jessy John, Rachel A. Woolaver, Vince Popolizio, Samantha M. Y. Chen, Huaibin Ge, Alexandra L. Krinsky, Monika Vashisht, Yonatan Kramer, Zhangguo Chen, Jing H. Wang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Differential responses to immune checkpoint inhibitors (ICI) may be attributed to tumor-intrinsic factors or environmental cues; however, these mechanisms cannot fully explain the variable ICI responses in different individuals. Here, we investigate
Externí odkaz:
https://doaj.org/article/f5b78caa49bf4ebaae7aefd9334011c3
Autor:
Xiaoguang Wang, Brittany C. Waschke, Rachel A Woolaver, Samantha M. Y. Chen, Zhangguo Chen, Jing H. Wang
Publikováno v:
Protein & Cell, Vol 11, Iss 7, Pp 472-482 (2020)
Abstract Immunotherapy has been applied successfully to treat B-cell lymphomas in preclinical models or clinical settings. However, immunotherapy resistance is a major challenge for B-cell lymphoma treatment. To overcome this issue, combinatorial the
Externí odkaz:
https://doaj.org/article/d9e84d707dd3487cac150e395a2a17fd
Autor:
Yik Chun Wong, Wan Liu, Lok Yan Yim, Xin Li, Hui Wang, Ming Yue, Mengyue Niu, Lin Cheng, Lijun Ling, Yanhua Du, Samantha M Y Chen, Ka-Wai Cheung, Haibo Wang, Xian Tang, Jiansong Tang, Haoji Zhang, Youqiang Song, Lisa A Chakrabarti, Zhiwei Chen
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009647 (2021)
HIV-1 functional cure requires sustained viral suppression without antiretroviral therapy. While effector-memory CD8+ T lymphocytes are essential for viremia control, few vaccines elicit such cellular immunity that could be potently recalled upon vir
Externí odkaz:
https://doaj.org/article/e61ea9ee96c84779a615ee17725cd595
Autor:
Antonio Jimeno, Rachel A Woolaver, Xiaoguang Wang, Alexandra L Krinsky, Brittany C Waschke, Samantha M Y Chen, Vince Popolizio, Andrew G Nicklawsky, Dexiang Gao, Zhangguo Chen, Xiao-Jing Wang, Jing Hong Wang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Antitumor immunity is highly heterogeneous between individuals; however, underlying mechanisms remain elusive, despite their potential to improve personalized cancer immunotherapy. Head and neck squamous cell carcinomas (HNSCCs) vary signi
Externí odkaz:
https://doaj.org/article/26f856b3ea3f4c039114e8c84bba4f37
Publikováno v:
IEEE Transactions on Electron Devices. 70:443-448
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