Zobrazeno 1 - 10
of 4 191
pro vyhledávání: '"M Wheeler"'
Autor:
Sarah M. Waldherr, Marina Han, Aleen D. Saxton, Taylor A. Vadset, Pamela J. McMillan, Jeanna M. Wheeler, Nicole F. Liachko, Brian C. Kraemer
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-19 (2024)
Abstract Pathological tau disrupts protein homeostasis (proteostasis) within neurons in Alzheimer’s disease (AD) and related disorders. We previously showed constitutive activation of the endoplasmic reticulum unfolded protein response (UPRER) tran
Externí odkaz:
https://doaj.org/article/1dbc62a4684b4673b78505934d8b0d3a
Autor:
Raymond M. Wheeler
Publikováno v:
Frontiers in Science, Vol 2 (2024)
Externí odkaz:
https://doaj.org/article/58404b4511ca471eb79e86e181f4240d
Autor:
Elizabeth A. Werren, Emily R. Peirent, Henna Jantti, Alba Guxholli, Kinshuk Raj Srivastava, Naama Orenstein, Vinodh Narayanan, Wojciech Wiszniewski, Mateusz Dawidziuk, Pawel Gawlinski, Muhammad Umair, Amjad Khan, Shahid Niaz Khan, David Geneviève, Daphné Lehalle, K. L. I. van Gassen, Jacques C. Giltay, Renske Oegema, Richard H. van Jaarsveld, Rafiullah Rafiullah, Gudrun A. Rappold, Rachel Rabin, John G. Pappas, Marsha M. Wheeler, Michael J. Bamshad, Yao-Chang Tsan, Matthew B. Johnson, Catherine E. Keegan, Anshika Srivastava, Stephanie L. Bielas
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-15 (2024)
Abstract CSMD1 (Cub and Sushi Multiple Domains 1) is a well-recognized regulator of the complement cascade, an important component of the innate immune response. CSMD1 is highly expressed in the central nervous system (CNS) where emergent functions o
Externí odkaz:
https://doaj.org/article/08dbba4aad0f4fdba2b94ba2c9076513
Autor:
Jess M. Bunchek, Mary E. Hummerick, LaShelle E. Spencer, Matthew W. Romeyn, Millennia Young, Robert C. Morrow, Cary A. Mitchell, Grace L. Douglas, Raymond M. Wheeler, Gioia D. Massa
Publikováno v:
Journal of Plant Interactions, Vol 19, Iss 1 (2024)
Fresh, nutritious, palatable produce for crew consumption on long-duration spaceflight missions may provide health-promoting, bioavailable nutrients and enhance the dietary experience. VEG-04A and VEG-04B explored growing leafy greens on the Internat
Externí odkaz:
https://doaj.org/article/a235b1c892914edf9c64d04504c3b739
Autor:
Raymond M. Wheeler, LaShelle E. Spencer, Ruqayah H. Bhuiyan, Matthew A. Mickens, Jess M. Bunchek, Edzard van Santen, Gioia D. Massa, Matthew W. Romeyn
Publikováno v:
Journal of Plant Interactions, Vol 19, Iss 1 (2024)
Space habitats typically have elevated CO2 and NASA is considering growing leafy greens in space to supplement astronauts’ diets. Dragoon’ and ‘Outredgeous’ lettuce, ‘Amara’ mustard, ‘Extra Dwarf’ pak choi, shungiku, ‘Red Russian’
Externí odkaz:
https://doaj.org/article/b368196a85904f97a92decdfc14cedad
Autor:
R.M. Staebler, J. Liggio, K.L. Hayden, Z. Oldham, R.L. Mittermeier, S.M. Li, K. MacKay, G.R. Wentworth, T.W. Tokarek, S.C. Smyth, C. Mihele, A. Leithead, M. Wheeler
Publikováno v:
Atmospheric Environment: X, Vol 23, Iss , Pp 100280- (2024)
The identification and reduction of methane sources is considered an important part of the fight to stem greenhouse gas (GHG) emissions to the atmosphere. One of the largest industrial contributors to national GHG emissions in Canada is the Alberta O
Externí odkaz:
https://doaj.org/article/7efda74a77bc455bb70825ddb63d0352
Autor:
Eric Venner, Karynne Patterson, Divya Kalra, Marsha M. Wheeler, Yi-Ju Chen, Sara E. Kalla, Bo Yuan, Jason H. Karnes, Kimberly Walker, Joshua D. Smith, Sean McGee, Aparna Radhakrishnan, Andrew Haddad, Philip E. Empey, Qiaoyan Wang, Lee Lichtenstein, Diana Toledo, Gail Jarvik, Anjene Musick, Richard A. Gibbs, the All of Us Research Program Investigators
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Disparities in data underlying clinical genomic interpretation is an acknowledged problem, but there is a paucity of data demonstrating it. The All of Us Research Program is collecting data including whole-genome sequences, health records, a
Externí odkaz:
https://doaj.org/article/1c6ea528141443f1ab6c586d02aa9e33
Autor:
Eric Venner, Karynne Patterson, Divya Kalra, Marsha M. Wheeler, Yi-Ju Chen, Sara E. Kalla, Bo Yuan, Jason H. Karnes, Kimberly Walker, Joshua D. Smith, Sean McGee, Aparna Radhakrishnan, Andrew Haddad, Philip E. Empey, Qiaoyan Wang, Lee Lichtenstein, Diana Toledo, Gail Jarvik, Anjene Musick, Richard A. Gibbs, on behalf of the All of Us Research Program Investigators
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5b809086973a49148087172a206a4e61
Autor:
Joseph Lykins, Matthew J. Moschitto, Ying Zhou, Ekaterina V. Filippova, Hoang V. Le, Tadakimi Tomita, Barbara A. Fox, David J. Bzik, Chunlei Su, Seesandra V. Rajagopala, Kristin Flores, Furio Spano, Stuart Woods, Craig W. Roberts, Cong Hua, Kamal El Bissati, Kelsey M. Wheeler, Sarah Dovgin, Stephen P. Muench, Martin McPhillie, Colin W.G. Fishwick, Wayne F. Anderson, Patricia J. Lee, Mark Hickman, Louis M. Weiss, Jitender P. Dubey, Hernan A. Lorenzi, Richard B. Silverman, Rima L. McLeod
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108477- (2024)
Summary: Toxoplasma gondii causes morbidity, mortality, and disseminates widely via cat sexual stages. Here, we find T. gondii ornithine aminotransferase (OAT) is conserved across phyla. We solve TgO/GABA-AT structures with bound inactivators at 1.55
Externí odkaz:
https://doaj.org/article/4214ce2e3d344bdb89d711a4b2786ce4
Break down the misconceptions of the Internet of Things by examining the different security building blocks available in Intel Architecture (IA) based IoT platforms. This open access book reviews the threat pyramid, secure boot, chain of trust, and t