Zobrazeno 1 - 10
of 26
pro vyhledávání: '"M Wayne Saville"'
Autor:
Vivek Subbiah, Alexander Guminski, James Strauss, Vivek Bhadri, Nam Bui, Jose Mejia Oneto, M Wayne Saville, Sangeetha Srinivasan, Nathan Yee, Michael Zakharian, Sant Chawla, Vineet Kwatra, Mia Weiss, Rosalind Wilson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/54c73d8b20bd4c61afc2529e809fc8f4
Autor:
Vivek Subbiah, Ravi Murthy, Alexander Guminski, Ding Wang, Vivek Bhadri, Nam Bui, Jose Mejia Oneto, Kamalesh Sankhala, M Wayne Saville, Sangeetha Srinivasan, Robert Steffner, Nathan Yee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/c55cf2e4612745f8907f9de4fc8f5a4c
Autor:
M. Wayne Saville, Vivek Subbiah, Ding Wang, Ravi Murthy, Sangeetha Srinivasan, Vivek Bhadri, Jose M. Mejia Oneto, Nam Bui, Alexander Guminski, Kamalesh Kumar Sankhala, Robert J. Steffner, Nathan Yee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Cancer immunotherapies have been very successful in recent times; however, they benefit only a subset of patients and have varying response rates across tumor types. Conversely, conventional chemotherapies are effective in a large group of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7e0128c40109c5ceb0c236ae15ac3c
https://doi.org/10.1136/jitc-2020-sitc2020.0416
https://doi.org/10.1136/jitc-2020-sitc2020.0416
Autor:
M. Wayne Saville, Mia C. Weiss, Vivek Bhadri, Jose M. Mejia Oneto, Vivek Subbiah, Nam Bui, Alexander Guminski, Vineet Kwatra, Kathleen Batty, Sangeetha Srinivasan, Michael Zakharian, Nathan Yee, Rosalind Wilson, Sant P. Chawla, James Strauss
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundConventional chemotherapeutics lack specificity for tumor tissue and usually have anarrow therapeutic index. SQ3370, a novel therapy that activates doxorubicin (Dox) at the tumor sitewhile minimizing systemic exposure, is based on intratumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe377ba9f9fcf5734a721b513d9c463
https://doi.org/10.1136/jitc-2021-sitc2021.367
https://doi.org/10.1136/jitc-2021-sitc2021.367
Autor:
Vivek Bhadri, Jose M. Mejia Oneto, Vivek Subbiah, Nam Bui, Robert J. Steffner, Ding Wang, M. Wayne Saville, Madhawa De Silva, Sangeetha Srinivasan, Alexander Guminski, Nathan Yee
Publikováno v:
Cancer Research. 81:CT225-CT225
Conventional chemotherapeutic agents are effective for a broad array of patients, but have limited dosing capabilities, lack specificity, and often result in systemic toxicity. Conversely, newer cancer immunotherapies have been successful but benefit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcadcca0300f658c82244e168cbb556f
https://doi.org/10.1158/1538-7445.am2021-ct225
https://doi.org/10.1158/1538-7445.am2021-ct225
Autor:
Chelsea M. Johnson, Vincent Ribrag, Guillaume Cartron, Sheeba K. Thomas, Asher Chanan-Khan, Thomas Ly, Krish Patel, John M. Pagel, Reda Bouabdallah, M. Wayne Saville, Jean-Marie Michot, Erin Reid, Frederic Peyrade, Tycel Phillips, William G. Wierda, David Liebowitz, Gilles Salles
Publikováno v:
Blood. 134:4079-4079
Introduction: XmAb13676 is a humanized bispecific antibody that binds both CD20 and CD3 in order to recruit cytotoxic T cells to kill CD20 expressing malignant cells. Interim results of an ongoing first-in-human, dose-escalation study (XmAb13676-01;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::444932511f149665329265cf952bf94e
https://doi.org/10.1182/blood-2019-128564
https://doi.org/10.1182/blood-2019-128564
Autor:
Alice S. Mims, Asad Bashey, Koichi Takahashi, Wendy Stock, Farhad Ravandi, Raya Mawad, Chelsea M. Johnson, Thomas Ly, James M. Foran, Hagop M. Kantarjian, M. Wayne Saville, K. Gary Vanasse, Bhavana Bhatnagar, William Blum
Publikováno v:
Blood. 132:763-763
Background: Blasts and leukemic stem cells of acute myeloid leukemia (AML) as well as several other hematologic malignancies express CD123, potentially providing a target for novel therapies. XmAb14045 (also known as SQZ622) is a potent bispecific an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a5b9840c008c1e936a8422b7005d4b8
https://doi.org/10.1182/blood-2018-99-119786
https://doi.org/10.1182/blood-2018-99-119786
Autor:
John Catalano, Peter Ganly, Tadeusz Robak, M. Wayne Saville, Sergey I. Moiseev, Anna Dmoszynska, Ilya Zyuzgin, Christian H. Geisler, Krzysztof Warzocha, Nancy Valente, Philippe Solal-Celigny, Caroline Dartigeas, Javier Loscertales, Marco Montillo, Jörg Maurer, Michael Wenger, Loree Larratt, Myriam Mendila, Boris V. Afanasiev, András Rosta
Publikováno v:
Journal of Clinical Oncology. 28:1756-1765
Purpose Rituximab, a monoclonal antibody that targets the CD20 cell surface antigen, has clinical activity in patients with non-Hodgkin's lymphoma and other B-lymphocyte disorders when administered alone or in combination with chemotherapy. Promising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60f542cb3bb8bd7dbf936f723452ed4
https://doi.org/10.1200/jco.2009.26.4556
https://doi.org/10.1200/jco.2009.26.4556
Autor:
David T. Scadden, Bruce J. Dezube, Jeannette Y. Lee, Jamie H. Von Roenn, Steven A. Miles, A. Friedman-Kien, Mary A Fletcher, Susan E. Krown, Lawrence D. Kaplan, Timothy P. Cooley, Jerome E. Groopman, M. Wayne Saville
Publikováno v:
AIDS. 16:421-429
Objective To assess the efficacy, safety and tolerance of oral 9-cis-retinoic acid in HIV-infected patients with Kaposi's sarcoma. Methods Sixty-six patients with AIDS-related Kaposi's sarcoma were enrolled at 14 centers; 60 received the study medica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da78d2e21a345d54e8fd4f93d59f7075
https://doi.org/10.1097/00002030-200202150-00014
https://doi.org/10.1097/00002030-200202150-00014
Publikováno v:
Annals of Pharmacotherapy. 30:62-76
OBJECTIVE: To review the in vitro, animal, and clinical data on immune-based therapies for treatment of HIV infection. DATA SOURCES: An extensive MEDLINE search was performed for interleukins, interferons, immunotoxins, tumor necrosis factor (TNF)-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16bc3b0b2bf1d0bb61705f66282c2e0
https://doi.org/10.1177/106002809603000111
https://doi.org/10.1177/106002809603000111