The synthesis and evaluation of benzofuranones as β-Lactamase substrates

Autor: R. F. Pratt, D. Cabaret, M. Wakselman, S. A. Adediran, B Drouillat

Publikováno v: Bioorganic & Medicinal Chemistry. 9:1175-1183

6- and 7-Carboxy-3-phenylacetamido-3H-1-benzofuran-2-one have been synthesized as potential beta-lactamase substrates and/or inhibitors. These compounds were prepared by lactonization of the corresponding, appropriately substituted phenylglycines. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb48f9da00cc02e3ce2a77324ee1634
https://doi.org/10.1016/s0968-0896(00)00345-x

Functionalized depsipeptides, substrates and inhibitors of β-lactamases and DD-peptidases

Autor: R. F. Pratt, Y. Xub, D. Cabaret, J. Liu, M. Wakselman

Publikováno v: Bioorganic & Medicinal Chemistry. 2:757-771

A series of derivatives of phenyl phenylacetylglycinates (aryl phenaceturates) with a carboxylate substituent meta to the oxygen of the phenoxide leaving group and a functionalized methylene group in the ortho- or para-position have been synthesized.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df77733d667b92b7c1d1368bdb97ac48
https://doi.org/10.1016/s0968-0896(00)82175-6

ChemInform Abstract: Synthesis, Hydrolysis, and Evaluation of 3-Acylamino-3,4-dihydro-2-oxo-2H-1,3-benzoxazinecarboxylic Acids and Linear Azadepsipeptides as Potential Substrates/Inhibitors of β-Lactam-Recognizing Enzymes

Autor: M. Garcia Gonzalez, R. F. Pratt, S. A. Adediran, D. Cabaret, M. Wakselman

Publikováno v: ChemInform. 33

The title compounds can be considered as stabilized aza analogs of previously studied dihydrobenzopyranones and linear depsipeptides, which behave as substrates or inhibitors of β-lactamases. Treatment of substituted hydrazides 9b and 9b′ with a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc8e16b911b8a6cbb3dcee8488e6dbe4
https://doi.org/10.1002/chin.200205186

Synthesis, resolution, and absolute configuration of BpAib, a benzophenone-containing, C-alpha-tetrasubstituted alpha-amino acid

Autor: K. Wright, M. Wakselman, J.-P. Mazaleyrat, A. Moretto, M. Crisma, F. Formaggio, C. Toniolo

Publikováno v: 30th European Peptide Symposium, Helsinki, 2008
info:cnr-pdr/source/autori:Wright K., Wakselman M., Mazaleyrat J.-P., Moretto A., Crisma M., Formaggio F., Toniolo C./congresso_nome:30th European Peptide Symposium/congresso_luogo:Helsinki/congresso_data:2008/anno:2008/pagina_da:/pagina_a:/intervallo_pagine
30th European Peptide Symposium, pp. 54–55, Helsinki, Finland, 31 agosto-5 settembre 2008
info:cnr-pdr/source/autori:K. Wright, M. Wakselman, J.-P. Mazaleyrat, A. Moretto, M. Crisma, F. Formaggio, C. Toniolo/congresso_nome:30th European Peptide Symposium/congresso_luogo:Helsinki, Finland/congresso_data:31 agosto-5 settembre 2008/anno:2009/pagina_da:54/pagina_a:55/intervallo_pagine:54–55

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::63a85020280377a839c7537034848d74
http://www.cnr.it/prodotto/i/104461

Synthesis and Spectroscopic Characterization of Enantiopure Protected trans-4-Amino-1-Oxyl-2,2,6,6-Tetramethylpiperidine-3-Carboxylic Acid (trans b-TOAC)

Autor: K. Wright, A. de Castries, M. Sarciaux, F. Formaggio, C. Toniolo, A. Toffoletti, M. Wakselman, J.-P. Mazaleyrat

Publikováno v: Tetrahedron letters 46 (2005): 5573–5576.
info:cnr-pdr/source/autori:K. Wright, A. de Castries, M. Sarciaux, F. Formaggio, C. Toniolo, A. Toffoletti, M. Wakselman, and J.-P. Mazaleyrat/titolo:Synthesis and Spectroscopic Characterization of Enantiopure Protected trans-4-Amino-1-Oxyl-2,2,6,6-Tetramethylpiperidine-3-Carboxylic Acid (trans b-TOAC)./doi:/rivista:Tetrahedron letters/anno:2005/pagina_da:5573/pagina_a:5576/intervallo_pagine:5573–5576/volume:46

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::85ce335b0f013b5abddbe8a5a7b03638
http://www.cnr.it/prodotto/i/15206