Výsledky vyhledávání - "M W, van der Linden"

Soluble CD95 concentrations are increased in patients with severe systemic lupus erythematosus, but not in their first degree relatives

Autor: M W van der Linden, R. G. J. Westendorp, T.W.J. Huizinga, Lucien A. Aarden, T van Lopik

Publikováno v: Annals of the rheumatic diseases, 60(3), 237-241. BMJ Publishing Group
Annals of the Rheumatic Diseases, 60(3), 237-241. BMJ Publishing Group

OBJECTIVE—Plasma concentrations of soluble CD95 (sCD95) are raised in patients with systemic lupus erythematosus (SLE) before clinical relapses become manifest. Increased sCD95 concentrations may therefore be a familial characteristic that is assoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e70073969631e219b5fd87d10a8432a
https://doi.org/10.1136/ard.60.3.237

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Neuropsychiatric systemic lupus erythematosus is associated with imbalance in interleukin 10 promoter haplotypes

Autor: M W van der Linden, M J Rood, T Q T Tong, Cornelis L. Verweij, T.W.J. Huizinga, F. C. Breedveld, S E Borggreve, V. Keijsers

Publikováno v: Annals of the Rheumatic Diseases. 58:85-89

OBJECTIVE—To investigate the association of interleukin 10 (IL10) promoter polymorphisms and neuropsychiatric manifestations of systemic lupus erythematosus (SLE). METHODS—IL10 haplotypes of 11 healthy volunteers were cloned to confirm that in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35a8fc7e32ae83f186338fcbf03ac8d
https://doi.org/10.1136/ard.58.2.85

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Intermittent cyclophosphamide with prednisone versus placebo for polyneuropathy with IgM monoclonal gammopathy

Autor: H. Franssen, Krista Fischer, L. H. van den Berg, Henk M. Lokhorst, F. Schobben, M. Eurelings, L. L. Teunissen, J.M.F. Niermeijer, M. W. van der Linden, J.H.J. Wokke, Nicolette C. Notermans

Publikováno v: Neurology, 69(1), 50-59. Lippincott Williams and Wilkins

Background: The best treatment for polyneuropathy associated with IgM monoclonal gammopathy (MGUS) is unknown. Oral cyclophosphamide combined with prednisone showed limited efficacy in a previous open label pilot study. We therefore performed a doubl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7835025ee5dbc698460bb28013b49fd2
https://pubmed.ncbi.nlm.nih.gov/17606880

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Autoantibodies within families of patients with systemic lupus erythematosus are not directed against the same nuclear antigens

Autor: M W, van der Linden, R G, Westendorp, M, Zidane, L, Meheus, T W, Huizinga

Publikováno v: The Journal of rheumatology. 28(2)

The presence of antinuclear autoantibodies in systemic lupus erythematosus (SLE) is influenced by genetic factors. The presence of autoantibodies in healthy family members of patients has been reported. Our hypothesis was that autoantibodies are dire

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6d0367fcf048e05728991953dff3831c
https://pubmed.ncbi.nlm.nih.gov/11246662

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High interleukin-10 production in first-degree relatives of patients with generalized but not cutaneous lupus erythematosus

Autor: M W, van der Linden, R G, Westendorp, A, Sturk, W, Bergman, T W, Huizinga

Publikováno v: Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 48(5)

Preclinical research suggests that interleukin-10 (IL-10) is associated with susceptibility to and severity of systemic lupus erythematosus. Chronic cutaneous lupus erythematosus is thought to be immunogenetically different from systemic lupus erythe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b0cf09e1a977caa1c2e75ebe7b4f4dd
https://pubmed.ncbi.nlm.nih.gov/10979237

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TNF-308A and HLA-DR3 alleles contribute independently to susceptibility to systemic lupus erythematosus

Autor: M J, Rood, M V, van Krugten, E, Zanelli, M W, van der Linden, V, Keijsers, G M, Schreuder, W, Verduyn, R G, Westendorp, R R, de Vries, F C, Breedveld, C L, Verweij, T W, Huizinga

Publikováno v: Arthritis and rheumatism. 43(1)

To evaluate the respective contributions of tumor necrosis factor (TNF) promoter polymorphisms and HLA-DR alleles to susceptibility to systemic lupus erythematosus (SLE).TNF-238G/A and 308G/A promoter polymorphisms and HLA-DRB1 alleles were determine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c80c8076fbd634a28782dc93553aef7c
https://pubmed.ncbi.nlm.nih.gov/10643708

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Interleukin-10 as an explanation for pregnancy-induced flare in systemic lupus erythematosus and remission in rheumatoid arthritis

Autor: V. Deneys-Laporte, Twj Huizinga, F. C. Breedveld, M W van der Linden

Publikováno v: Rheumatology (Oxford, England). 38(6)

Rheumatoid arthritis (RA) and systemic lupus erythIL-10 production in human lymphocytes [6 ]. Increased ematosus (SLE) have in part overlapping clinical feaproduction of IL-10 may be of particular interest tures, but behave strikingly differently dur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b223e6330a6fa19f24c6e0bd4a7baa07
https://pubmed.ncbi.nlm.nih.gov/10402067

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