Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M W, Stahlhut"'
Autor:
M W, Stahlhut, D B, Olsen
Publikováno v:
Methods in enzymology. 275
Modern molecular biology techniques have provided valuable tools which allow for the expression of large amounts of enzyme in E. coli. For potential therapeutic targets such as HIV-1 reverse transcriptase, it is desirable that the enzyme studied is p
Publikováno v:
Cancer. 70(8)
Iron is essential for the growth of all living cells. One of the important intracellular roles for iron is in the activation of ribonucleotide reductase, the enzyme that catalyzes the first step in DNA synthesis. Thus, the intracellular iron level ma
Publikováno v:
Cancer. 68(11)
Iron is essential for the growth of all cells, including tumor cells. The authors previously reported that a variety of transplantable tumors grew faster and larger in mice that were on an iron-rich diet compared with those on an iron-deficient diet.
Publikováno v:
Cancer. 66(2)
The relationship of iron-binding proteins to prognosis was studied in 50 children at the Children's Hospital of Philadelphia, newly diagnosed with Hodgkin's disease (HD). There were five patients with Stage I, 18 with Stage II, 14 with Stage III, and
Publikováno v:
American Journal of Epidemiology. 124:329-331
Serum samples from 10 individuals were divided into six subsamples. Three of these were tested for ferritin by radioimmunoassay. All six samples from each subject were then tested for selenium by neutron activation assay. There was no significant dif
Publikováno v:
Hepato-gastroenterology. 35(1)
The serum ferritin level was detected by radioimmunoassay in 142 patients with hepatocellular carcinoma (HCC). Serum ferritin level was raised (greater than ng/ml) in 38% (54/142) of patients with HCC. There was no difference in serum ferritin levels
Publikováno v:
Progress in clinical and biological research. 175
These studies suggest that a) the levels of serum ferritin are closely related to the prognosis of patients with neuroblastoma; b) the increased amounts of ferritin in the serum of patients with neuroblastoma are, in part, derived from the tumor; c)
Publikováno v:
Cancer research. 44(9)
Fifteen nude mice were inoculated with a human neuroblastoma cell line and 14 with a human primary hepatocellular carcinoma cell line. Human ferritins were detected in the sera of the mice which developed tumors. Of 14 mice bearing human neuroblastom
Publikováno v:
Journal of the National Cancer Institute. 76(6)
Serum ferritin is present in two forms--a glycosylated form that results from active secretion by cells and a nonglycosylated form that is directly released by damaged cells. Glycosylated ferritin binds to concanavalin A (Con A) through the glucose a
Publikováno v:
Cancer. 62(6)
Serum ferritin frequently is elevated in patients with neuroblastoma. Isoferritins extracted from neuroblastoma tumors and cells in culture show a wide range from basic (rich in L subunit) to acidic (rich in H subunit) isoferritins. Total ferritin is