Zobrazeno 1 - 10
of 20
pro vyhledávání: '"M W, Roe"'
Autor:
M E Lancaster, A Kuznetsov, J.F. Worley rd, Louis H. Philipson, M P Rosenberg, M. W. Roe, I D Dukes
Publikováno v:
Journal of Biological Chemistry. 269:27787-27790
Glucose stimulation of pancreatic beta-cell insulin secretion is closely coupled to alterations in ion channel conductances and intracellular Ca2+ ([Ca2+]i). To further examine this relationship after augmentation of voltage-dependent K+ channel expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8d0674a1ab397b825af1058131ad746
https://doi.org/10.1016/s0021-9258(18)46851-2
https://doi.org/10.1016/s0021-9258(18)46851-2
Publikováno v:
Journal of Biological Chemistry. 269:21127-21135
Rapid, transient induction of c-fos transcription follows treatment of cells with insulin and other growth factors. This is mediated through the serum response element (SRE), which binds the serum response factor (SRF), as well as accessory factors s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cf3b8cd2ec4706699d7316a4768c100
https://doi.org/10.1016/s0021-9258(17)31939-7
https://doi.org/10.1016/s0021-9258(17)31939-7
Publikováno v:
The Journal of biological chemistry. 276(33)
Swelling of hepatocytes and other epithelia activates volume-sensitive ion channels that facilitate fluid and electrolyte efflux to restore cell volume, but the responsible signaling pathways are incompletely defined. Previous work in model HTC rat h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5fd1de1e01ecfda8de8aab335ceac5c
https://pubmed.ncbi.nlm.nih.gov/11413133
https://pubmed.ncbi.nlm.nih.gov/11413133
Publikováno v:
The Journal of biological chemistry. 275(27)
Despite abundant evidence for changes in mitochondrial membrane permeability in tumor necrosis factor (TNF)-mediated cell death, the role of plasma membrane ion channels in this process remains unclear. These studies examine the influence of TNF on i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa97a5df7a6b6d80d0766733f6b9f6aa
https://pubmed.ncbi.nlm.nih.gov/10783394
https://pubmed.ncbi.nlm.nih.gov/10783394
Autor:
M W, Roe, J F, Worley, A A, Mittal, A, Kuznetsov, S, DasGupta, R J, Mertz, S M, Witherspoon, N, Blair, M E, Lancaster, M S, McIntyre, W R, Shehee, I D, Dukes, L H, Philipson
Publikováno v:
The Journal of biological chemistry. 271(50)
Voltage-dependent delayed rectifier K+ channels regulate aspects of both stimulus-secretion and excitation-contraction coupling, but assigning specific roles to these channels has proved problematic. Using transgenically derived insulinoma cells (bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::723326b060f01dedebfff1b11c2ad0bc
https://pubmed.ncbi.nlm.nih.gov/8943282
https://pubmed.ncbi.nlm.nih.gov/8943282
Autor:
Iain D. Dukes, Yoshiharu Tokuyama, Jeppe Sturis, Jiping Tang, M. W. Roe, Kenneth S. Polonsky, Jennings F. Worley, Louis H. Philipson, Graeme I. Bell
Publikováno v:
The American journal of physiology. 270(1 Pt 1)
Development of non-insulin-dependent diabetes mellitus (NIDDM) is associated with defects in glucose-stimulated insulin secretion. We have investigated Zucker diabetic fatty rats (ZDF), an animal model of NIDDM, and found that, compared with control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9723ce810839016c90427e5d131349f2
https://pubmed.ncbi.nlm.nih.gov/8772485
https://pubmed.ncbi.nlm.nih.gov/8772485
Autor:
L H, Philipson, M P, Rosenberg, A, Kuznetsov, M E, Lancaster, J F, Worley, M W, Roe, I D, Dukes
Publikováno v:
The Journal of biological chemistry. 269(45)
Glucose stimulation of pancreatic beta-cell insulin secretion is closely coupled to alterations in ion channel conductances and intracellular Ca2+ ([Ca2+]i). To further examine this relationship after augmentation of voltage-dependent K+ channel expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b5ea1ff636f43570fa1185ed816a36f
https://pubmed.ncbi.nlm.nih.gov/7961701
https://pubmed.ncbi.nlm.nih.gov/7961701
Publikováno v:
The Journal of biological chemistry. 269(33)
Rapid, transient induction of c-fos transcription follows treatment of cells with insulin and other growth factors. This is mediated through the serum response element (SRE), which binds the serum response factor (SRF), as well as accessory factors s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8bce49735dffed11bb16ac5de9526b6c
https://pubmed.ncbi.nlm.nih.gov/8063733
https://pubmed.ncbi.nlm.nih.gov/8063733
Autor:
M W, Roe, L H, Philipson, C J, Frangakis, A, Kuznetsov, R J, Mertz, M E, Lancaster, B, Spencer, J F, Worley, I D, Dukes
Publikováno v:
The Journal of biological chemistry. 269(28)
Non-insulin-dependent diabetes mellitus (NIDDM) is a metabolic disease associated with abnormal insulin secretion, the underlying mechanisms of which are unknown. Glucose-dependent signal transduction pathways were investigated in pancreatic islets d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::938efb3a9ea515a48d615e57b5c7b45b
https://pubmed.ncbi.nlm.nih.gov/8034570
https://pubmed.ncbi.nlm.nih.gov/8034570
Publikováno v:
The Journal of biological chemistry. 269(20)
Glucose stimulation of islet beta-cell insulin secretion is initiated by membrane depolarization and an elevation in intracellular free calcium concentration ([Ca2+]i) from a combination of influx through depolarization-activated Ca2+ channels and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c2edf47132977c6595a92c3f1468d7d
https://pubmed.ncbi.nlm.nih.gov/8182038
https://pubmed.ncbi.nlm.nih.gov/8182038