Zobrazeno 1 - 10
of 15
pro vyhledávání: '"M W, Linder"'
Publikováno v:
Drug Metabolism Reviews. 31:247-271
A number of genes involved in foreign compound metabolism are inducibleby polycyclic aromatic hydrocarbons and the study of their molecular regulationis an active area of research. The prototypical...
Autor:
D, Weintraub, M W, Linder
Publikováno v:
Depression and anxiety. 12(1)
Publikováno v:
Rapid Communications in Mass Spectrometry. 5:203-205
A standard commercial thermospray interface was modified by replacing the stainless-steel capillary by another stainless-steel capillary with a larger internal diameter. A fused-silica capillary was then placed within the whole length of the stainles
Autor:
M W, Linder, R, Valdes
Publikováno v:
Annals of clinical and laboratory science. 29(2)
Metabolism and disposition of foreign compounds, including pharmaceuticals, is dependent upon a host of factors. However, a genetic basis for individuality in drug metabolism has long been recognized and more recently has been confirmed. It is now we
Publikováno v:
Molecular pharmacology. 53(6)
Glucocorticoids (GCs) repress both basal and polyaromatic hydrocarbon-induced expression of the glutathione S-transferase Ya1 gene (gstA2) in isolated rat hepatocytes and rat liver in vivo. Transient transfection experiments with HepG2 cells were use
Autor:
M W, Linder, P E, Keck
Publikováno v:
Clinical chemistry. 44(5)
Therapeutic drug monitoring (TDM) for certain tricyclic antidepressants (TCAs) and lithium is supported on the basis of clearly defined therapeutic ranges. TDM is of particular importance in individuals whose pharmacokinetic behavior may differ from
Publikováno v:
Clinical chemistry. 43(2)
Pharmacogenetics is the study of the linkage between an individual's genotype and that individual's ability to metabolize a foreign compound. Differences in metabolism of therapeutics can lead to severe toxicity or therapeutic failure by altering the
Autor:
M W, Linder, R, Valdes
Publikováno v:
Clinical chemistry. 40(8)
The presence of salicylates in urine reduces the signal in Emit assays (Syva), potentially yielding false-negative drugs-of-abuse screening results. We demonstrate that the principal urinary metabolite of salicylate, salicyluric acid (SUA; 2-hydroxyb
Publikováno v:
Clinical chemistry. 40(4)
During routine drug analysis with the Syva d.a.u. Emit immunoassays we observed a high frequency of urines with lower rates of changes in absorbance (delta A R) than the rate for a drug-free urine calibrator. Many of these urines contained salicylate
Publikováno v:
Medical education. 26(6)
Summary. This paper describes the efforts of the Department of Family and Community Health at Sultan Qaboos University in providing opportunities for the development of ‘hands-on’ problem-solving skills appropriate for Oman. The curriculum of the