Zobrazeno 1 - 6
of 6
pro vyhledávání: '"M W, Kunkel"'
Autor:
ANDREANI, ALDO, BURNELLI, SILVIA, GRANAIOLA, MASSIMILIANO, LEONI, ALBERTO, LOCATELLI, ALESSANDRA, MORIGI, RITA, RAMBALDI, MIRELLA, VAROLI, LUCILLA, FARRUGGIA, GIOVANNA, CALONGHI, NATALIA, STEFANELLI, CLAUDIO, MASOTTI, LANFRANCO, M. W. Kunkel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4094::4d72506ea757e1742eef9da1220cd74b
http://hdl.handle.net/11585/33539
http://hdl.handle.net/11585/33539
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(2)
Doxorubicin plays an important role in the treatment of leukemias, lymphomas, and a variety of carcinomas. Tumor cell resistance to doxorubicin is often associated with expression of the multidrug resistance gene MDR1, which codes for the drug efflux
Autor:
R, Calaluce, M W, Kunkel, G S, Watts, M, Schmelz, J, Hao, J, Barrera, M, Gleason-Guzman, R, Isett, M, Fitchmun, G T, Bowden, A E, Cress, B W, Futscher, R B, Nagle
Publikováno v:
Molecular carcinogenesis. 30(2)
Interactions between extracellular matrix (ECM) proteins and prostate carcinoma cells provide a dynamic model of prostate tumor progression. Previous work in our laboratory showed that laminin-5, an important member of a family of ECM glycoproteins e
Publikováno v:
Anti-cancer drug design. 12(8)
We have used a cell line-directed screening approach (CDSA) to identify novel inhibitors of the thioredoxin reductase signaling pathway which contributes to the transformed phenotype of some human tumors. Two 2-imidazolyl disulfide compounds, previou
Publikováno v:
The Journal of biological chemistry. 268(5)
To address the role of protein phosphatases in regulating hormonal responses in mammalian cells, we investigated the effects of okadaic acid, a potent inhibitor of protein phosphatases 1 and 2A, on epinephrine and prostaglandin E1 stimulation of cAMP
Autor:
Massimiliano Granaiola, Rita Morigi, Carole Grasso, Angelika Burger, Mirella Rambaldi, Aldo Andreani, Alberto Leoni, Gerhard Kelter, Silvia Burnelli, Laura Landi, Lucilla Varoli, Heinz-Herbert Fiebig, Alessandra Locatelli, Cecilia Prata, Michael V. Berridge, Mark W. Kunkel
This paper reports the synthesis of compounds formed by two indole systems separated by a heterocycle (pyridine or piperazine). As a primary screening, the new compounds were submitted to the National Cancer Institute for evaluation of antitumor acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cc4ecbc64b4348dce090bce2651595
https://europepmc.org/articles/PMC2754042/
https://europepmc.org/articles/PMC2754042/